Vaccine design methods and protocols
"This volume provides a practical guide providing step-by-step protocol to design and develop vaccines for human diseases. Divided into three volumes, Volume 1: Vaccines for Human Diseases guides readers through an introductory section on future challenges for vaccinologists and the immunologic...
| Otros Autores: | |
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| Formato: | Libro |
| Idioma: | Inglés |
| Publicado: |
New York, NY :
Humana Press
[2022]
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| Edición: | Second edition |
| Colección: | Methods in molecular biology (Clifton, N.J.) ;
2410 Springer protocols (Print) |
| Materias: | |
| Ver en Universidad de Navarra: | https://unika.unav.edu/discovery/fulldisplay?docid=alma991005795299708016&context=L&vid=34UNAV_INST:VU1&search_scope=34UNAV_TODO&tab=34UNAV_TODO&lang=es |
| Sumario: | "This volume provides a practical guide providing step-by-step protocol to design and develop vaccines for human diseases. Divided into three volumes, Volume 1: Vaccines for Human Diseases guides readers through an introductory section on future challenges for vaccinologists and the immunological mechanism of vaccines. Chapters focus on design of human vaccines for viral, bacterial, fungal, and parasitic diseases as well as tumor vaccines. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design : Methods and Protocols, Second Edition, Volume 1: Vaccines for Human Diseases aims to be a useful practical guide to researchers to help further their study in this field" |
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| Notas: | Preface .Part I. Vaccines: introduction 1. Challenges for vaccinologists in the first half of the twenty first century 2. Principles in immunology for the design and development of vaccines 3. Revisiting the principles of designing a vaccine 4. Status of COVID-19 pandemic before the administration of vaccine .Part II. Trends in vaccinology 5. mRNA vaccines to protect against diseases 6. Artificial intelligence in vaccine and drug design .Part III. Vaccines for human viral diseases 7. Vaccines targeting numerous coronavirus antigens. ensuring broader global population coverage: multi-epitope and multi-patch vaccines 8. Use of micro-computed tomography to visualize and quantify COVID-19 vaccine efficiency in free-breathing hamsters 9. Design of replication-competent VSV- and Ervebo-vectored vaccines against SARS-CoV-2 10. CRISPR engineering of bacteriophage T4 to design vaccines against SARS-CoV-2 and emerging pathogens 11. Techniques for developing and assessing immune responses induced by synthetic DNA vaccines for emerging infectious diseases 12. Towards determining the epitopes of the structural proteins of SARS-CoV-2 13. Development. production and characterization of hepatitis B subviral envelope particles as a third-generation vaccine 14. Generation of CpG-Recoded Zika virus vaccine candidates .Part IV. Vaccines for human bacterial diseases 15. Salmonella uptake into gut-associated lymphoid tissues: implications for targeted mucosal vaccine design and delivery 16. Development of human recombinant leptospirosis vaccines 17. Induction of T-cell responses by vaccination of a streptococcus pneumoniae whole cell vaccine 18. Development of a bacterial nanoparticle vaccine against escherichia coli 19. Construction of novel live genetically modified BCG vaccine candidates using recombineering tools 20. An update on tuberculosis vaccines 21. Structure-based design of diagnostics and vaccines for Lyme disease 22. Development of a SONIX vaccine to protect against ehrlichiosis .Part V. Vaccines for human parasitic diseases 23. Development of the anti-Leishmanial vaccine 24. In silico design of recombinant chimera T cell peptide epitope vaccines for visceral Leishmaniasis 25. Pre-clinical assessment of the immunogenicity of experimental Leishmania vaccines 26. Production of oral vaccines based on retrovirus virus-like particles pseudotyped with protozoan-surface proteins 27. A Fast-Track phenotypic characterization of plasmodium falciparum vaccine antigens through Lyse-Reseal erythrocytes mediated delivery (LyRED) of RNA interference for targeted translational repression 28. Plasmodium falciparum antigen expression in Leishmania parasite: a way forward for live attenuated vaccine development 29. Molecular characterization of a vector-based candidate antigen using the 3'-RACE and genome walking methods and in silico analysis of the correspondent protein for vaccine design and development 30. In vitro culture of plasmodium falciparum for the production of mature gametocytes for performing standard membrane feeding assay and infection of anopheles spp. 31. Plasmodium berghei infection in BALB/c mice model as an animal model for malaria disease research 32. Standard membrane feeding assay for malaria transmission studies .Part VI. Development of cancer vaccines 33. Generation of tumor targeted dendritic cell vaccines with improved immunogenic and migratory phenotype 34. Monocytes as a cellular vaccine platform to induce anti-tumor immunity 35. Beyond sequencing: prioritizing and delivering neoantigens for cancer vaccines .Part VII. Vaccines for allergy 36. Proteomics for development of food allergy vaccines .Part VIII. Vaccines for toxins 37. Estimating vaccine potency using antibody-based competition assays |
| Descripción Física: | v. <1 > : ill. en noir et en coul., couv. ill. en coul. ; 26 cm |
| Bibliografía: | Incluye referencias bibliográficas al final de cada capítulo e índices. |
| ISBN: | 9781071618837 |
