Plasticity in multiple sclerosis from molecular to system level, from adaptation to maladaptation

Plasticity occurs at multiple levels in multiple sclerosis (MS), from cells to synapses, from myelin to axons, from individual regions to large-scale brain networks. A growing body of evidence supports the notion that the course of MS and its extremely heterogeneous clinical manifestations might be...

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Bibliographic Details
Other Authors: Daniel Zeller (auth), Zeller, Daniel, editor (editor), Rocca, Maria A. (Maria Assunta), editor
Format: eBook
Language:Inglés
Published: [Lausanne, Switzerland] : Frontiers Media SA 2016
[2016]
Series:Frontiers research topics.
Subjects:
See on Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009741017206719
Description
Summary:Plasticity occurs at multiple levels in multiple sclerosis (MS), from cells to synapses, from myelin to axons, from individual regions to large-scale brain networks. A growing body of evidence supports the notion that the course of MS and its extremely heterogeneous clinical manifestations might be the net result of disease burden and compensatory capacity. As a consequence, identifying what can be considered as "positive" plasticity and what, on the contrary, is a maladaptive reorganization is a very attractive goal which might help to develop therapeutic strategies able to promote the individual adaptive capacity. The aim of this Research Topic forum is to provide a state of the art update on the diversity of available data in humans with MS, derived from the many studies performed using different research tools, including immunological, neurophysiological and neuroimaging techniques which have addressed neuroplasticity at multiple system level, from motor, to visual, and cognitive. Synopsis of recent advances of plasticity research in MS aims to broaden the view across systems and techniques and to stimulate further studies on this emerging topic.
Item Description:"Published in: Frontiers in Neurology" -- front cover.
Physical Description:1 online resource (72 pages) : illustrations; digital file(s)
Also available in print form
Audience:Specialized.
Bibliography:Includes bibliographical references.
ISBN:9782889197644