Dose finding by the continual reassessment method
As clinicians begin to realize the important role of dose-finding in the drug development process, there is an increasing openness to ""novel"" methods proposed in the past two decades. In particular, the Continual Reassessment Method (CRM) and its variations have drawn much atte...
| Autor principal: | |
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| Formato: | Libro electrónico |
| Idioma: | Inglés |
| Publicado: |
Boca Raton :
Taylor & Francis
2011.
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| Edición: | 1st edition |
| Colección: | Chapman & Hall/CRC biostatistics series ;
41. |
| Materias: | |
| Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009627931506719 |
| Sumario: | As clinicians begin to realize the important role of dose-finding in the drug development process, there is an increasing openness to ""novel"" methods proposed in the past two decades. In particular, the Continual Reassessment Method (CRM) and its variations have drawn much attention in the medical community, though it has yet to become a commonplace tool. To overcome the status quo in phase I clinical trials, statisticians must be able to design trials using the CRM in a timely and reproducible manner. A self-contained theoretical framework of the CRM for researchers and graduate students wh |
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| Notas: | A Chapman & Hall book. |
| Descripción Física: | 1 online resource (204 p.) |
| Bibliografía: | Includes bibliographical references. |
| ISBN: | 9780429138744 9781420091526 |
