Capillary fluid exchange regulation, functions, and pathology

The partition of fluid between the vascular and interstitial compartments is regulated by forces (hydrostatic and oncotic) operating across the microvascular walls and the surface areas of permeable structures comprising the endothelial barrier to fluid and solute exchange, as well as within the ext...

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Detalles Bibliográficos
Otros Autores: Scallan, Joshua (-), Huxley, Virgina H., Korthuis, Ronald J.
Formato: Libro electrónico
Idioma:Inglés
Publicado: [San Rafael, Calif.?] : Morgan & Claypool 2010.
Colección:Colloquium series on integrated systems physiology ; #3.
Materias:
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009622342106719
Tabla de Contenidos:
  • 1. Fluid movement across the endothelial barrier
  • The starling equation
  • Hydraulic conductivity
  • Assessment of diffusive permeability
  • Convective solute transport across the microvascular walls
  • Capillary the morphology varies among organs
  • Transendothelial filtration modifies vascular function
  • 2. The interstitium
  • Composition, structure and three-dimensional organization of the extracellular matrix in the interstitial spaces
  • Solute exclusion and osmotic amplification
  • Compliance and hydraulic conductance in the extracellular matrix
  • Fluid flow in the interstitium modifies the function of tissue cells
  • 3. The lymphatic vasculature
  • Anatomy and nomenclature of the lymphatic vasculature
  • Lymph formation
  • Interstitial fluid pressure and its influence on lymph flow
  • Lymphatic solute permeability
  • Propulsion of lymph by the lymphatic muscle pump
  • Lymphangiogenesis
  • Tumors and lymphatic metastasis
  • Cessation of lymph flow and its immunological consequences
  • 4. Pathophysiology of edema formation
  • The margin of safety against edema formation, edema safety factors
  • Vasogenic edema
  • Hypoproteinemia
  • Permeability edema and inflammation
  • Neurogenic inflammation
  • Myxedema
  • Lymphedema
  • References.