(+)-catechin (?)-catechin (?)-epicatechin ?-glucosidase inhibition BDNF CREB CaMKII Italian chocolate angiotensin-converting enzyme (ACE) inhibitory activity anti-inflammatory properties antidiabetic capacity antioxidant capacity athlete behavior bioactive compounds bioactive peptides bioavailability biomarkers blood pressure cacao chiral separation chocolate classification cocoa cocoa beans cocoa by-product cocoa processing cocoa proteins cocoa-based ingredients cohort study