“…They underpin markets, protect the rights and safety of citizens and ensure the delivery of public goods and services. …”

“…Written for biostatisticians, pharmacometricians, clinical developers, and statistical programmers involved in the design, analysis, and interpretation of clinical trials, as well as students in graduate and postgraduate programs in statistics or biostatistics, the book touches on a wide variety of topics, including dose-response and dose-escalation designs; sequential methods to stop trials early for overwhelming efficacy, safety, or futility; Bayesian designs that incorporate historical data; adaptive sample size re-estimation; adaptive randomization to allocate subjects to more effective treatments; and population enrichment designs. …”

Tabla de Contenidos: “…4.3 Process Considerations -- 4.4 Economic Considerations -- 4.5 Operational Considerations -- 4.6 Maintenance Considerations -- 4.7 Safety and Emergency Considerations -- 4.8 Construction Considerations -- 4.9 Appearance -- 4.10 Future Expansion -- 4.11 Considerations for Solids Handling Plant -- 4.12 Plot Buildings -- 4.13 Forming Plots -- 4.14 Plot Layout Rules of Thumb -- Further Reading -- 5 Planning of Layout Activities -- 5.1 General -- 5.2 Abbreviations/Standards and Codes of Practice/Terminology -- 5.2.1 Abbreviations -- 5.2.2 Standards and Codes -- 5.2.2.1 International Standards -- 5.2.2.2 European Standards -- 5.2.2.3 British Standards -- 5.2.2.4 US Standards -- 5.2.3 Terminology -- 5.3 The Project Life Cycle -- 5.4 The Organization of Conceptual Design -- 5.5 The Organization of Front End Engineering Design -- 5.6 The Organization of Detailed Design -- 5.7 The Organization of Design for Construction -- 5.8 The Organization of Post Construction Design -- 5.8.1 Site Level Redesign -- 5.8.2 Posthandover Optimization -- 6 Methods for Layout, Conception, and Development -- 6.1 General -- 6.2 Abbreviations/Standards and Codes/Terminology -- 6.2.1 Abbreviations -- 6.2.2 Standards and Codes -- 6.2.2.1 European Standards -- 6.2.2.2 British Standards -- 6.2.2.3 US Standards -- 6.2.3 Terminology -- 6.3 Design Reviews -- 6.3.1 Informal Design Reviews -- 6.3.1.1 Consultation With Equipment Suppliers -- 6.3.1.2 Consultation With Electrical/Software Partners -- 6.3.1.3 Consultation With Civils/Buildings Partners -- 6.3.1.4 Consultation With Peers/More Senior Engineers -- 6.3.2 Formal Design Reviews -- 6.3.2.1 Interdisciplinary Design Review -- 6.3.2.2 Value Engineering Review -- 6.3.2.3 Safety Engineering Review -- 6.4 Economic Optimization -- 6.5 Rating Classification Methods -- 6.5.1 Area Classification (Electrical)…”

Tabla de Contenidos: “…8.1 - RAPID-N -- 8.1.1 - Scientific Module -- 8.1.2 - Industrial Plants and Units Module -- 8.1.3 - Natural-Hazards Module -- 8.1.4 - Natech Risk-Analysis Module -- 8.1.5 - Outlook -- 8.2 - PANR -- 8.3 - TRAS 310 and TRAS 320 -- 8.3.1 - TRAS 310 "Precautions and Measures Against the Hazard Sources Precipitation and Flooding" -- 8.3.1.1 - Scope of Application -- 8.3.1.2 - Methodological Approach of TRAS 310 -- 8.3.1.3 - Hazard Source Analysis -- 8.3.1.3.1 - Simplified hazard source analysis -- 8.3.1.3.2 - Detailed hazard source analysis -- 8.3.1.3.3 - Consideration of climate change -- 8.3.1.4 - Determination of Threatened Safety-Relevant Parts of Establishments and Installations -- 8.3.1.5 - Determination of Possible Causes of Major Accidents -- 8.3.1.6 - Specification of Scenarios and Protection Aims -- 8.3.1.7 - Elaboration of Protection Concepts for Scenarios -- 8.3.1.8 - Review of Protection Concepts -- 8.3.1.9 - Determination of Accident Scenarios -- 8.3.1.10 - Specification of Measures to Mitigate the Effects of Major Accidents -- 8.3.1.11 - Planning for Emergencies -- 8.3.1.12 - Design Criteria for the Consideration of Climate Change -- 8.3.2 - TRAS 320 "Precautions and Measures Against the Hazard Sources Wind, Snow Loads and Ice Loads" -- 8.3.3 - Summary -- 8.4 - Other methodologies -- References -- Chapter 9 - Quantitative Methods for Natech Risk Assessment -- 9.1 - ARIPAR -- 9.1.1 - Framework of the ARIPAR-GIS Natech Module -- 9.1.2 - The ARIPAR-GIS Software -- 9.1.3 - The Natech Package of the ARIPAR-GIS Software -- 9.1.4 - Input Data and Calculation Procedure -- 9.1.5 - Equipment Vulnerability Models -- 9.1.6 - Output -- 9.2 - RISKCURVES -- References -- Chapter 10 - Case-Study Application I: RAPID-N -- 10.1 - Earthquake scenario -- 10.2 - Chemical Facility Description -- 10.3 - Natech Risk Analysis -- 10.3.1 - Damage Analysis…”

“…It presents a state-of-the-art examination of the subject for: Scientists and researchers who are engaged in pharmaceutical/clinical research and development of TCMs Those in regulatory agencies who make decisions in the review and approval process of TCM regulatory submissions Biostatisticians who provide statistical support to assess clinical safety and effectiveness of TCMs and related issues regarding quality control and assurance as well as to test for consistency in the manufacturing processes for TCMs This book covers all of the statistical issues encountered at various stages of pharmaceutical/clinical development of a TCM. …”

“…The book has been updated to include more on safety and the latest technology including: - fixed instruments using the new lower wattage high efficiency lamps in combination with dichronic reflectors - an increase in the availability, reliability, range and usage of 'moving light' technology based on remotely controlled instruments. …”

“…MC offers advantages over mammalian collagen due to its water solubility, low immunogenicity, safety, biocompatibility, antimicrobial activity, functionality, and low production costs. …”

Tabla de Contenidos: “…-- Degradation Assessment of Natural Stone Claddings over Their Service Life: Comparison between Tehran (Iran) and Lisbon (Portugal) -- Most Frequent Problems of Building Structures of Urban Apartment Buildings from 2nd Half of 19th Century and the Start of 20th Century -- Critical Analysis about Emerging Technologies for Building's Fac ̧ade Inspection -- Microclimate of Air Cavities in Ventilated Roof and Fac ̧ade Systems in Nordic Climates -- Structural Performance Assessment of Innovative Hollow Cellular Panels for Modular Flooring System -- Insurance Policies for Condition-Based Maintenance Plans of ETICS -- Integrated Building Maintenance and Safety Framework: Educational and Public Facilities Case Study…”

Tabla de Contenidos: “…-- Employee assistance programs -- Part II The Role of Leadership -- Chapter 3 Compassionate Leadership: The key to psychological safety at work -- Get to know your people -- Dealing with confidentiality: how much should you tell them? …”

“…Bulgaria needs to provide more support for families, including quality childcare country-wide, and make staying in the country more attractive by raising productivity, fostering the creation of good-quality formal jobs and reinforcing the social safety net.SPECIAL FEATURE: BETTER JOBS AND INCOMES…”

“…The empathic relationship between therapist and client provides the safety that the client needs to be able to go deeply into those painful emotions, hitherto felt to be too frightening, and to reclaim the healthy need, action tendency and more adaptive emotions connected to the painful emotions.In the therapy session Les helps the client to access both her core feelings of being unseen and unloved and her automatic ways of interrupting her emotions. …”

Tabla de Contenidos: “…5.8.2 Key Findings and Contributions -- 5.8.2.1 Integration of Mathematical Models -- 5.8.2.2 Application of Artificial Intelligence -- 5.8.2.3 Future Directions -- 5.8.2.4 Improved Security and Public Safety -- 5.8.2.5 Efficiency and Automation -- 5.8.3 Importance of Continued Research in Enhancing Surveillance Systems -- 5.8.3.1 Advancements in Technology -- 5.8.3.2 Addressing Complex Challenges -- 5.8.3.3 Improving Accuracy and Efficiency -- 5.8.3.4 Enhancing Threat Detection and Prevention -- 5.8.3.5 Real-World Application and Impact -- References -- Key Terms -- Chapter 6 A Study on Object Detection Using Artificial Intelligence and Image Processing-Based Methods -- 6.1 Introduction -- 6.2 Role of Artificial Intelligence in Image Analysis -- 6.2.1 Object Detection and Recognition -- 6.2.2 Image Segmentation -- 6.2.3 Medical Image Analysis -- 6.2.4 Virtual Reality (VR) and Augmented Reality (AR) -- 6.3 How Artificial Intelligence Can Enhance Traditional Image Processing Algorithms and Enable New Applications -- 6.3.1 Image Restoration -- 6.3.2 Super Resolution -- 6.3.3 Style Transfer -- 6.4 Benefits of Artificial Intelligence and Image Processing Methods -- 6.5 Ethical Considerations Associated with AI and Image Processing -- 6.5.1 Privacy and the Protection of Data -- 6.5.2 Bias and Discrimination Artificial Intelligence (AI) Algorithms -- 6.5.3 Informed Approval and Transparency -- 6.5.4 Deep Fakes and the Spread of Misinformation -- 6.5.5 Trust and Safety -- 6.5.6 Accountability and Responsibility -- 6.6 Conclusion -- References -- Chapter 7 Application of Fuzzy Approximation Method in Pattern Recognition Using Deep Learning Neural Networks and Artificial Intelligence for Surveillance -- 7.1 Introduction -- 7.2 Preliminaries -- 7.2.1 Neural Network -- 7.2.2 Pattern Recognition -- 7.2.3 Self-Organizing Maps (or Kohonen Maps)…”

“…Meanwhile, due to their wide usage and high safety criticality, any security or privacy problems in them pose direct threats to end users and stakeholders. …”

“…., establishing reference datasets or sharing trained models without sacrificing model explainability, robustness or safety). Pragmatic answers to all these points are paramount to enable a transition of the current large body of literature on AI for networking from academic exercises to solutions integrated in production systems. …”

“…His techniques apply to everything from culture to strategy, customer safety to market share. They won't just help you avoid catastrophe: they'll help you improve profitability and business value, too. …”

“…Now, The Bellwether Group fills the gap on public literature on this subject, showing business and IT decision-makers how to use new GSOC techniques and technologies to increase operational resiliency in the face of security, safety, and other disruptive events, while at the same time reducing staffing and system-wide costs. …”

“…Evaluating the long term performance and safety of such systems demands an understanding of the coupled mechanical behavior and transport properties of salt. …”

“…Yet when we hunker down and try to live in a bubble of safety, we can cut ourselves off from the joy life has to offer. …”

“…However, many unanswered questions remain on the efficacy and safety of anticoagulants in selected cancer subgroups, and in primary and secondary prevention settings, where anticoagulation needs to be balanced on the risk of bleeding complications. …”

“…Themes such as innovation and sustainability, health and safety, as well as identity, flexibility and affordability are all of relevance for the Police’s accommodation strategy. …”