“…Antimicrobial resistance is the intrinsic capability of microorganisms to survive unfavorable conditions; such traits are mainly transferrable through movable genetic elements, enabling the rapid and homogeneous diffusion of resistance genes over diverse ecosystems and sectors including human medicine, veterinary medicine, and the environment. …”

“…Dysfunctions of helicases cause various diseases, such as xeroderma pigmentosum (XP), premature aging syndrome, cancer and immunodeficiency, in humans. Moreover, recent genetic analyses revealed that mutations in helicase-encoding genes are frequently found in patients of specific diseases. …”

“…One major constraint hampering our understanding of these signal transduction processes in plants has been the lack or slow pace of application of molecular genomic and genetics knowledge in the form of gene function. In the post-genomic era, one of the major challenges is investigation and understanding of multiple genes and gene families regulating a particular physiological and developmental aspect of plant life cycle. …”

“…In the past decade, great progress has been made in understanding the pathobiology and genetics of this blinding disease, as well as in finding new therapies for its treatment. …”

“…It was also reported that mobile genetic elements often carry both resistance determinants and virulence-modulating genes, which favors the co-selection of both traits. …”

Tabla de Contenidos: “…Case Studies -- Case Study 1: Quantified Timed Get Up and Go (QTUG) Test -- Algorithm Development -- Model Development -- Prototype Development -- Case Study 2: Ambient Assessment of Daily Activity and Gait Velocity -- Case Study 3: Training for Focused Living -- Lessons Learned -- The Installation Process -- Key Sensor Findings -- Data Quality -- User Engagement -- Summary -- References -- Chapter 9: Body-Worn, Ambient, and Consumer Sensing for Health Applications -- Changing the Way We Do Healthcare -- Sensing Context in Health Applications -- Hospital and Community-Based Sensing for Assessment and Diagnosis -- Monitoring Vital Signs -- Heart Rate -- Blood Pressure -- Temperature -- Respiratory Rate -- Blood Oxygenation -- Community-Based Sensing -- Home-Based Clinical Applications -- Chronic Disease Management -- Investigative and Episodic Monitoring -- Mobility and Behavioral Monitoring -- Biomechanical Rehabilitation -- Aggregation and Management -- The Smartphone as a Healthcare Platform -- Self-care Diagnostic Test Kits -- Enzymatic/Immunological Assays -- Enzymatic Test Strips -- Chromatic Wet Chemistry -- The Home Test Market -- Home Genetic Testing -- Key Drivers and Challenges -- Drivers and Challenges in Healthcare Systems -- Technology Drivers and Challenges -- Consumer Drivers and Challenges -- The Future of Sensor-Based Applications for Healthcare -- Summary -- References -- Chapter 10: Wellness, Fitness, and Lifestyle Sensing Applications -- Drivers and Barriers: Sports and Fitness Sensing -- Drivers for Sports and Fitness Sensing -- Barriers to Sports and Fitness Sensing -- Sports and Fitness Applications -- Supporting Wireless Technologies -- Fitness Sensing -- Clothing -- Sports Equipment Sensing -- Cycling -- Golf -- Sensing in Other Sports -- Sports and Fitness Statistics -- Activity and Well-Being…”

Tabla de Contenidos: “…Injury and Accident Data -- Historical Data -- Incidence Rates -- Injury and Illness Prevention Programs -- Workplace Injuries and Illnesses -- Compensation Insurance -- Crisis Management Plans -- Return to Work Programs -- A Focus on Prevention -- Disaster Preparation and Continuity Planning -- Workplace Violence -- Substance Abuse -- Physical Asset Protection -- Cyber Vulnerability and Liability -- Employee Communication and Safety Training -- Risk Management Techniques -- Metrics -- Suggested Study or Organizational Audit Activities -- Appendix A: Alphabetical Listing of Legal Issues -- Affirmative Action Plans (AAPs) -- Age Discrimination in Employment Act of 1967 (ADEA) -- Americans with Disabilities Act of 1990 (ADA) -- Australian Federal Privacy Act of 1988 -- Civil Rights Act of 1964 (Title VII) -- Common Law Doctrines -- Copyright Act of 1976 -- Davis-Bacon Act of 1931 -- Drug-Free Workplace Act of 1988 -- EEO Survey -- Employee Retirement Income Security Act of 1974 (ERISA) -- Executive Orders -- Fair Credit Reporting Act of 1970 (FCRA) -- Fair Labor Standards Act of 1938 (FLSA) -- Family and Medical Leave Act of 1993 (FMLA) -- Foreign Corrupt Practices Act of 1977 -- Genetic Information Nondiscrimination Act of 2008 (GINA) -- Glass Ceiling Act of 1991 -- Illegal Immigration Reform and Immigrant Responsibility Act of 1996 (IIRIRA) -- Immigration Reform and Control Act of 1986 (IRCA) -- International Labour Organization (ILO) -- International Trade Organizations -- Mine Safety and Health Act of 1977 (MSHA) -- Occupational Safety and Health Act of 1970 (OSHA) -- Organisation for Economic Co-operation and Development (OECD): Guidelines for Multinational Enterprises (MNEs) -- Patient Protection and Affordable Care Act of 2010 (PPACA, ACA, Obamacare) -- Pension Protection Act of 2006 (PPA) -- Privacy Act of 1974.…”

Tabla de Contenidos: “…-- Marginal cost of solar PV is getting cheaper -- Solar leasing and green bonds -- Biofuels and Food Inflation -- Energy security in disguise -- The "regulatory carrot" -- The "regulatory stick" -- Renewable Identification Numbers (RINs) -- The "ethanol blend wall" -- Food inflation and inequality -- Shortages and physical hoarding as flatteners -- Energy efficiency of biofuels -- Meat prices: "corn with legs" -- The super-cycle of farmland and agricultural logistical infrastructure -- Genetically modified crops -- A flatter agricultural world -- Notes -- Chapter 13 Flattener #10 - Fiscal, Monetary, and Macroeconomic Flatteners -- The "OPEC put" -- At what level would OPEC stop defending the price? …”

Tabla de Contenidos: “…La genèse d'un signe de justice urbain -- L'invention du pilori et de sa peine associée -- Un nouveau mot pour une nouvelle institution -- Un terreau fertile : les rituels d'humiliation publique antérieurs au pilori -- Enquête lexicographique : des mots, une institution -- Flandres, Artois, Picardie, Normandie : espaces et causes d'apparition du pilori -- L'influence des mutations économiques et sociales du XIIe siècle -- Une marque de protection et de propriété du marché -- Une institution au service de la "vengeance commune", des bourgeois ? …”

Tabla de Contenidos: “…Artificial intelligence -- 1.8.1. Genetic algorithms -- 1.8.2. Neural networks -- 1.8.3. …”

Tabla de Contenidos: “…Cocaine -- Methamphetamine -- Ecstasy (3,4-methylenedioxymethamphetamine - MDMA) -- "Bath salts" -- Methylphenidate -- Hallucinogens and dissociative agents -- -- Phencyclidine (PCP) -- Ketamine -- Lysergic acid (LSD) -- Dextromethorphan -- Inhalants -- Cannabinoids -- Conclusion -- References -- Chapter 7 Drug withdrawal syndromes in psychiatric patients in the emergency department -- Introduction -- Ethanol withdrawal -- Treatment -- Disposition of patients with ethanol withdrawal -- Sedative hypnotic drugs withdrawal -- Overview -- Gamma-hydroxybutyrate (GHB) withdrawal -- Opioid withdrawal -- References -- Section 3 Psychiatric illnesses -- Chapter 8 The patient with depression in the emergency department -- Introduction -- Clinical features -- Major depressive disorder -- Mood -- Psychomotor activity -- Vegetative function -- Cognition -- Special considerations -- Depression in the elderly -- Children and adolescents -- Postpartum depression -- Bipolar disorders -- Bipolar depression -- Manic episode -- Mood disorders caused by a general medical condition -- Mood disorders caused by medications or other substances -- Diagnostic strategies -- Management -- Emergency department stabilization -- Suicide risk management -- Conclusion -- References -- Chapter 9 Assessment of the suicidal patient in the emergency department -- Introduction -- Epidemiology -- Risk factors for suicide -- Gender -- Age -- Psychiatric illness -- Previous suicide attempt -- Access to firearms -- Marital status -- Chronic medical illnesses -- Sexual orientation -- Family history and genetics -- History of childhood abuse -- Other risk factors -- Protective factors -- The SADPERSONS scale -- The patient evaluation -- Suicidal ideation -- Suicide attempts -- Determination of risk -- Key indicators of a high-risk suicidal patient -- Management of the suicidal patient…”

Tabla de Contenidos: “…Methods and Strategies of Research -- Experimental Ablation -- Evaluating the Behavioral Effects of Brain Damage -- Producing Brain Lesions -- Stereotaxic Surgery -- Histological Methods -- Tracing Neural Connections -- Studying the Structure of the Living Human Brain -- Recording and Stimulating Neural Activity -- Recording Neural Activity -- Recording the Brain's Metabolic and Synaptic Activity -- Stimulating Neural Activity -- Neurochemical Methods -- Finding Neurons That Produce Particular Neurochemicals -- Localizing Particular Receptors -- Measuring Chemicals Secreted in the Brain -- Genetic Methods -- Twin Studies -- Adoption Studies -- Genomic Studies -- Targeted Mutations -- Antisense Oligonucleotides -- CRISPR-Cas Methods -- Chapter 6. …”

Tabla de Contenidos: “…Defining a strategy to get it to work with a multivariate time series model -- Laying the groundwork for the permutation approximation strategy -- Computing the SHAP values -- Identifying influential features with factor prioritization -- Computing Morris sensitivity indices -- Analyzing the elementary effects -- Quantifying uncertainty and cost sensitivity with factor fixing -- Generating and predicting on Saltelli samples -- Performing Sobol sensitivity analysis -- Incorporating a realistic cost function -- Mission accomplished -- Summary -- Dataset and image sources -- Further reading -- Chapter 10: Feature Selection and Engineering for Interpretability -- Technical requirements -- The mission -- The approach -- The preparations -- Loading the libraries -- Understanding and preparing the data -- Understanding the effect of irrelevant features -- Creating a base model -- Evaluating the model -- Training the base model at different max depths -- Reviewing filter-based feature selection methods -- Basic filter-based methods -- Constant features with a variance threshold -- Quasi-constant features with value_counts -- Duplicating features -- Removing unnecessary features -- Correlation filter-based methods -- Ranking filter-based methods -- Comparing filter-based methods -- Exploring embedded feature selection methods -- Discovering wrapper, hybrid, and advanced feature selection methods -- Wrapper methods -- Sequential forward selection (SFS) -- Hybrid methods -- Recursive Feature Elimination (RFE) -- Advanced methods -- Model-agnostic feature importance -- Genetic algorithms -- Evaluating all feature-selected models -- Considering feature engineering -- Mission accomplished -- Summary -- Dataset sources -- Further reading -- Chapter 11: Bias Mitigation and Causal Inference Methods -- Technical requirements -- The mission -- The approach…”

Tabla de Contenidos: “…Active Disturbance Rejection Control -- The Experiment -- Study Preparation -- Experimental Results -- Conclusions and Future Work -- References -- Industrial Robots -- Research on Modular Design of Perpendicular Jointed Industrial Robots -- Introduction -- Modular Division and Conceptual Design -- Subdivision and Detailed Design of Execute Module -- Conclusions -- References -- Online Path Planning for Industrial Robots in Varying Environments Using the Curve Shortening Flow Method -- Introduction -- Problem -- State of the Art -- Curve Shortening Flow Method -- Basic Principle -- Equation -- Numerical Solution -- Extension to Three Dimensions -- Results -- Summary and Outlook -- References -- Parallel-Populations Genetic Algorithm for the Optimization of Cubic Polynomial Joint Trajectories for Industrial Robots -- Introduction -- Formulation of Cubic Polynomial Joint Trajectory -- PGA1 Formulation -- PGA2 Formulation -- Optimization Technique Using GA -- Application Examples -- Example 1: Comparison with lin83 and tse98 -- Example 2: With Dynamic Constraints -- Conclusions -- References -- Robotics Assembly Applications -- Integrative Path Planning and Motion Control for Handling Large Components -- Introduction -- Motivation -- Path Planning and Motion Control for Robots -- Integrative Path Planning and Control Concept -- Implementation -- Application -- Summary and Outlook -- References -- Automatic Configuration of Robot Systems - Upward and Downward Integration -- Introduction -- Scope of the Paper -- Existing Approaches -- Conceptual Design -- Paradigm Shift -- Characteristics of Modules -- Function Modelling -- Experimental Setup -- Conclusions and Outlook -- References -- Process and Human Safety in Human-Robot-Interaction - A Hybrid Assistance System for Welding Applications -- Introduction…”

Tabla de Contenidos: “…Model or Theory-Based Tests and Test Batteries -- INFLUENCE ON TESTING SELECTION OF DIFFERENT OBJECTIVES FOR TESTING -- EXPECTED DIRECTIONS IN TEST DEVELOPMENT -- REMAINING BARRIERS TO TEST DEVELOPMENT -- RECOMMENDATIONS FOR FURTHER RESEARCH OR DEVELOPMENT -- References -- Human Neurobehavioral Toxicology Testing -- RATIONALES FOR DEVELOPING TEST BATTERIES -- Finland's Institute of Occupational Health Approach -- Problem-Based Approach -- Approach Recommended by the World Health Organization -- Neurobehavioral Evaluation System Approach -- TARGET ORGAN EFFECTS -- Neurotoxic Chemicals -- Exposure Populations -- Behaviors Affected by Many Chemicals -- NIOSH Recommendations -- Recommendations of the American Conference of Governmental Industrial Hygienists -- POTENTIAL OF TEST BATTERIES TO ASSESS TARGET ORGAN HEALTH EFFECTS -- DEVELOPMENT EFFORTS UNDER WAY -- NOTES -- ACKNOWLEDGMENT AND DISCLAIMER -- References -- Neurobehavioral Tests: Problems, Potential, and Prospects -- TESTS CURRENTLY IN USE -- SOME SPECIFIC POINTS -- Methods in Behavioral Toxicology (Hanninen) -- Current Status of Test Development (Williamson) -- Human Neurobehavioral Tests (Anger) -- THE ADEQUACY OF CURRENT TESTS -- SOME NEW DEVELOPMENTS IN COMPUTER-BASED ASSESSMENT -- Cognitive Componential Models -- Inferential Systems -- IMPLICATIONS FOR NEUROBEHAVIORAL ASSESSMENT -- References -- PART II ASSESSMENT OF ANIMAL MODELS: WHAT HAS WORKED AND WHAT IS NEEDED -- Exposure to Neurotoxins Throughout the Life Span: Animal Models for Linking Neurochemical Effects to Behavioral Consequences -- NEUROCHEMICAL CHANGES DURING DEVELOPMENT AND AGING -- THE CHOLINERGIC SYSTEM IN BEHAVIOR -- EFFECTS OF PRENATAL EXPOSURE TO DFP: FROM BIRTH TO WEANING -- EFFECTS OF EARLY POSTNATAL EXPOSURE TO DFP -- EFFECTS OF EXPOSURE TO DFP: SENESCENT RATS -- Genetic (Strain-Specific) Differences in Effects…”

Tabla de Contenidos: “…A Mathematical Model for Prevention -- Primary Versus Secondary Prevention -- Behavioral Versus Biomedical Approaches -- REDUCING EXPOSURE AND TRANSMISSION -- Individual Factors -- Sexual and Other Behaviors -- Perception of Risk -- Link Between Perceived Risk and Protective Behaviors -- Personal Skills -- Behavioral Methods -- Theoretical Approaches to STD and HIV Risk Reduction -- Individual-Focused Interventions -- Community-Based Interventions -- School-Based Interventions -- Mass Media Interventions -- Other Methods -- Prophylaxis -- Condoms -- Other Contraceptives and Dual Protection -- Partner Notification and Treatment -- Screening -- REDUCING DURATION OF INFECTION -- Early Diagnosis and Treatment -- Diagnostic Tests for STDs -- Culturing -- Microscopy -- Antibody Detection Tests -- Antigen Detection Tests -- Tests Based on Genetic Markers -- Treatment for STDs -- Barriers to Diagnosis and Effective Treatment -- CONCLUSIONS -- REFERENCES -- 5 Current STD-Related Services -- CLINICAL SERVICES -- Health Care Professionals and Prevention Activities -- Dedicated Public STD Clinics -- Persons Served -- Services Provided -- Effectiveness -- Federal Role -- Community-Based Clinics -- School- and University-Based Settings -- Private Sector Settings -- Managed Care Organizations and Other Health Plans -- Growing Role of Managed Care -- Effect of Managed Care on STD Prevention -- Services and Programs of Managed Care Organizations -- Government Initiatives Related to managed Care and STDs -- NATIONAL SURVEILLANCE AND INFORMATION SYSTEMS -- National Notifiable Disease Reporting -- Limitations of the Reporting System -- Surveillance and Public STD Programs -- Other Surveillance Systems -- Health Behavior Surveys -- Measuring and Evaluating Program Effectiveness -- Data Management, Utilization, and Limitations -- Information Systems Development…”

“…Topics by chapters are: molecular mechanism of action, immunosensors , laboratory studies, molecular modeling, weed resistance, community response, use of herbicides in biotech culture, gene flow, herbicides and risk, herbicides persistence. …”

Tabla de Contenidos: “…Figure 2.1 Pourcentage d'élèves à chaque niveau de compétence sur l'échelle PISA de compréhension de l'écrit et position relative des pays, cycle d'évaluation 2000 du PISA -- Figure 2.2 Performance des élèves sur l'échelle PISA de compréhension de l'écrit et dépenses par élève dans les pays de l'OCDE -- Figure 2.3 Performance en compréhension de l'écrit et incidence du milieu familial dans les pays de l'OCDE, cycle d'évaluation 2000 du PISA -- Figure 2.4 Pourcentage d'élèves scolarisés dans des établissements ayant au moins quelques pouvoirs de décision concernant les aspects suivants de la politique et de la gestion les concernant, pays de l'OCDE, cycle d'évaluation 2000 du PISA -- Figure 2.5 Écarts de performance en compréhension de l'écrit au sein des établissements scolaires et entre eux dans les pays de l'OCDE, cycle d'évaluation 2000 du PISA -- Figure 2.6 Effet du milieu socio-économique de l'élève et de la composition socio-économique de l'établissement scolaire sur les performances en compréhension de l'écrit dans les pays de l'OCDE, cycle d'évaluation 2000 du PISA -- Figure 3.1 Selon les chefs d'établissement interrogés, la pénurie ou l'inadéquation de l'offre d'enseignants gêne-t-elle l'apprentissage des élèves ? (2000) -- Figure 3.2 Selon les chefs d'établissement interrogés, la pénurie ou l'inadéquation de l'offre d'enseignants gêne -t-elle l'apprentissage des élèves ? …”

“…Thus, inducing transcription of previously silent genes and suppressing active genes in response to the extracellular signal can result in acquiring new functions by the cells. …”