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13681
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13682Publicado 2010Tabla de Contenidos: “…Granger -- Polémicas de una exposición: Les chefs-d’oeuvre du Pardo au Musée de Genève / M. García Julliard -- L’échange artistique de 1941 entre l’Espagne et la France / M. …”
Biblioteca Universitat Ramon Llull (Otras Fuentes: Biblioteca Universidad de Deusto)Libro -
13683por Organisation de coopération et de développement économiques.Tabla de Contenidos: “…Moyenne pondérée des droits de douane des États-Unis après les cycles de négociation du GATT (avant Genève = 100) -- Figure 4. Production, exportations et investissement direct étranger dans le monde…”
Publicado 1999
Libro electrónico -
13684por Klump, RainerTabla de Contenidos: “…Einführung -- II. Zur Genese und Methodik unterschiedlicher Gesamtwerke -- 1. …”
Publicado 2024
Libro electrónico -
13685Publicado 2024Tabla de Contenidos: “…., -- Les guerres des Aigles de Savoie -- De la guerre de Septante Ans à la guerre de Cent Ans (fin XIIIe-milieu XIVe siècle) -- Le contrôle d'Ambronay, une démonstration de force) -- Du siège du château de La Corbière (1321) à la défaite de Varey (1325) -- Les grandes batailles des années 1330 -- L'éclatement de la guerre de Cent Ans, le concours savoyard à la cause des Valois -- Des conquêtes pour régner (1352-1355) -- L'expédition d'Amédée VI en Valais -- Les guerres au pays de Gex, à la chasse d'Hugues de Genève -- La bataille des Abrers (avril 1354) : escarmouche, embuscade ou débandade de l'ennemi -- La conquête du Faucigny, une opération réfléchie -- Les entreprises d'Amédée VI, entre aventures étrangères et guerres intestines (1355-1383) -- Le Comte Vert en Piémont : rébellions, compagnies mercenaires et nouvelles alliances -- De la croisade aux guerres italiennes : les effectifs des expéditions à l'étranger -- La guerre contre les Beaujeu, un apprentissage pour un jeune prince -- Le Comte Rouge, dernier prince guerrier (1383-1391) -- Le "marteau des Anglais" en Flandre -- Une nouvelle "croisade valaisanne" -- Les Tuchins du Canavais... un véritable guêpier -- Eentrée à Nice et l'aide offerte aux Visconti -- Le principat d'Amédée VIII (1393-1439), un îlot de paix ? …”
Libro electrónico -
13686Publicado 2020Tabla de Contenidos: “…Ausweitung der Vorsorgezone: Die Genese des precautionary principle 263 3.2.2. Deichgrafendämmerung: Kritik hydraulischer Gouvernementalität 273 3.2.3. …”
Libro electrónico -
13687Publicado 2011Tabla de Contenidos: “…Cover -- Praise for Extreme Money -- Extreme Money -- Contents -- Figures and tables -- Prologue: Hubris -- Sub-prime dialects -- Best in show -- The Physical Impossibility of Death in theMind of Someone Living -- Retreat -- Swiss inquisitions -- Idea of an investment -- Ambush -- Mega presentations -- Fording streams -- Liquidity and leverage -- Democracy of greed -- Pick and pay -- Black Sea real estate -- Life on the margin -- Racing days -- Dr Doom -- Extreme money -- Part 1: Faith -- Mirror of the times -- Some kinda money -- Trading places -- The invention of money -- Barbarous relic -- The real thing -- The Hotel New Hampshire -- Collapse -- Money machines -- Debt clock -- Money is nothing -- The mirrored room -- Money changes everything -- Mrs Watanabe goes to Wall Street -- FX Beauties Club -- Plutonomy -- Trickling down, trading up -- I shop, therefore I must be! …”
Libro electrónico -
13688Publicado 2013Tabla de Contenidos: “…Summary -- Introduction -- 1.1 Protein aggregation and amyloidoses -- 1.1.1 Mechanisms of amyloid fibril formation -- 1.1.2 Oligomer structural polymorphism: fibrillar and prefibrillar oligomers -- 1.1.3 Oligomer toxicity: common mechanism of pathogenesis -- 1.1.4 Amyloid formation is an inherent property of polypeptide chains: functional amyloid and disease unreleated amyloid -- 1.2 HypF-N: model protein of amyloid aggregation unrelated to disease -- 1.2.1 Function, structure and aggregation of HypF-N -- 1.2.2 HypF-N protofibrils interact with cell membranes originating a cytotoxic cascade -- 1.2.3 A causative link between the structure of HypF-N oligomers and their ability to cause cellular dysfunction -- 1.3 Alzheimer's disease -- 1.3.1 The Alzheimer phenotype -- 1.3.2 The elaborate processing of APP -- 1.3.3 The genetics of Alzheimer's disease -- 1.3.4 Peripheral cells as a tool to identify and test hypotheses on AD pathophysiology -- 1.3.5 Adult neurogenesis and stem cell technology for AD -- 1.4 Cholesterol and gangliosides in the central nervous system (CNS) -- 1.4.1 Brain cholesterol metabolism -- 1.4.2 Ganglioside metabolism -- 1.4.3 Lipid rafts -- 1.4.4 Role of cholesterol in AD -- 1.4.5 Role of gangliosides in AD -- 1.5 Aim of the study -- Materials & Methods -- 2.1 Materials -- 2.1.1 Chemicals -- 2.1.2 Fluorescent probes -- 2.1.3 Peptides and aggregation protocols -- 2.2 Cell cultures -- 2.3 Methods -- 2.3.1 Separation processes -- 2.3.2 Differentiation of human mesenchymal stromal cells -- 2.3.3 Modulation of membrane cholesterol levels -- 2.3.4 Modulation of membrane GM1 levels -- 2.3.5 Cholesterol content measurements -- 2.3.6 GM1 content measurements -- 2.3.7 Cell exposure to peptide aggregates -- 2.3.8 Analysis of aggregate interaction with the cells -- 2.3.9 Analysis of aggregate interaction with GM1 -- 2.3.10 Analysis of aggregate internalisation -- 2.3.11 Analysis of membrane permeability -- 2.3.12 Analysis of cytosolic Ca2+ dyshomeostasis -- 2.3.13 Evaluation of ROS production -- 2.3.14 Analysis of lipid peroxidation -- 2.3.15 Cytotoxicity assay and cell death analysis: apoptotic and necrotic markers -- 2.3.16 Steady-state fluorescence anisotropy -- 2.3.17 Atomic force microscopy (AFM) -- 2.3.18 Measurements of the fluorescence intensities -- 2.3.19 Statistical analysis -- Results -- 3.1 Results I -- 3.1.1 A protective role for lipid raft cholesterol against amyloidinduced membrane damage in human neuroblastoma cells -- 3.1.2 Aß42 oligomer binding to the cell surface and its cytotoxic effect are modulated by membrane cholesterol content -- 3.1.3 Aß42 oligomers colocalize with lipid rafts -- 3.1.4 Isolation and characterization of DRMs -- 3.1.5 Effects of ADDLs on lipid raft structural order -- 3.1.6 AFM imaging of supported DRMs purified from cells exposed to ADDLs -- 3.2 Results II -- 3.2.1 Lipid rafts mediate amyloid-induced calcium dyshomeostasis and oxidative stress in Alzheimer's disease -- 3.2.2 Lipid rafts are primary interaction sites for Aß42 oligomers at the plasma membrane -- 3.2.3 Cholesterol and GM1 mediate Aß42 accumulation at the plasma membrane -- 3.2.4 Cholesterol and GM1 mediate Ca2+ dyshomeostasis and extensive membrane permeabilization induced by Aß42 oligomers -- 3.2.5 GM1 modulates lipid peroxidation and cytotoxicity induced by Aß42 oligomers -- 3.2.6 GM1 mediates Aß42-induced Ca2+ dyshomeostasis, lipid peroxidation and cytotoxicity in rat cortical neurons -- 3.3 Results III -- 3.3.1 Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers -- 3.3.2 Membrane cholesterol content modulates oligomer cytotoxicity -- 3.3.3 Membrane cholesterol modulates oligomer-induced alteration of intracellular Ca2+ homeostasis and ROS levels -- 3.3.4 Cholesterol levels modulate membrane permeability to the oligomers -- 3.3.5 Membrane GM1 affects the cytotoxic and permeabilizing effects of HypF-N oligomers -- 3.3.6 GM1, rather than cholesterol, plays a dominant role in oligomer cytotoxicity and membrane permeability -- 3.4 Results IV -- 3.4.1 Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aß42 aggregate toxicity -- 3.4.2 Neuronal differentiation of hMSCs results in reduced levels of membrane GM1 -- 3.4.3 Neuronal differentiation of hMSCs reduces the interaction of Aß42 oligomers with the cell surface -- 3.4.4 Neuronal differentiation of hMSCs reduces Aß42 oligomerinduced intracellular Ca2+ dyshomeostasis and oxidative stress -- 3.4.5 Neuronal differentiation of hMSCs increases cell resistance to Aß42 aggregates Discussion -- 4.1 A protective role for lipid raft cholesterol against amyloid-induced membrane damage in human neuroblastoma cells -- 4.2 Lipid rafts mediate amyloid-induced calcium dyshomeostasis and membrane permeabilization in Alzheimer's fibroblasts -- 4.3 Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers -- 4.4 Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aß42 aggregate toxicity -- 4.5 Concluding remarks -- Abbreviations -- References…”
Libro electrónico -
13689Publicado 2023Tabla de Contenidos: “…Sustainable Food and Farming: When Public Perceptions Depart from Science -- 10.1 The Political Economy of Science Acceptance in Farming -- 10.2 Defining Sustainable Food -- 10.3 Case 1: "Green Revolution" Farming -- 10.4 Case 2: Industrial Farming -- 10.5 Case 3: Organic Food -- 10.6 Case 4: Genetically Modified Organisms (GMOS) -- 10.7 When Will Popular Resistance Block Uptake? …”
Libro electrónico -
13690Publicado 2000Tabla de Contenidos: “…/ Javier Bernal -- Una enfermedad y Mosén Jaume / Jaume Gené Nolla -- Cuestión de enamoramiento / Jorge Concepción Feliciano -- Y tú ¿por qué no? …”
991005236849706719 -
13691por Farrelly, Colleen M.Tabla de Contenidos: “…-- Querying and modifying data in Neo4j -- Basic query example -- More complicated query examples -- Summary -- References -- Chapter 13: Putting It All Together -- Technical requirements -- Introduction to the problem -- Ebola spread in the Democratic Republic of Congo - 2018-2020 outbreak -- Geography and logistics -- Introduction to GEEs -- Mathematics of GEEs -- Our problem and GEE formulation -- Data transformation -- Python wrangling -- GEE input -- Data modeling -- Running the GEE in Python -- Summary -- References -- Chapter 14: New Frontiers -- Quantum network science algorithms -- Graph coloring algorithms -- Max flow/min cut -- Neural network architectures as graphs -- Deep learning layers and connections -- Analyzing architectures -- Hierarchical networks -- Higher-order structures and network data -- An example using gene families -- Hypergraphs -- Displaying information -- Metadata -- Summary -- References -- Index -- Other Books You May Enjoy…”
Publicado 2024
Libro electrónico -
13692Publicado 2012Tabla de Contenidos: “…Main Arguments -- Identify the Call to Action and Work Backward -- Weed Out Vocalized Thinking -- Take Your Audience With You -- Curb People Pleasing and Puffing -- Make Not Having an Answer an Acceptable Answer -- Develop Strong and Succinct Presentation Skills -- Tweet-Sized Takeaways -- Chapter 6: Ensure a Return on Your Expectations -- Be Transparent -- Co-Create Means for Assessment -- Find Your Employee's Motivators -- Create a Coaching Culture -- Do it Early...and Often -- Be Open to Coaching -- Make Mistakes Teachable Moments -- Uphold Consequences -- Reward Outstanding Performance -- If it's Not a Fit, Let Them Go -- Tweet-Sized Takeaways -- Chapter 7: Keep Their Focus on Their Focus -- Zero Tolerance for Triangulation -- Always Have a Filter Question -- Say Yes By Saying No -- Use the Payoff as a Carrot -- Keep an Eye on the Two Steps Ahead -- Time Leadership Trumps Time Management -- To Do or to Delegate...Know the Difference -- Get of Your Own Way By Getting Out of Your Head -- Encourage a Praxis Approach -- Assign "Vice" Work -- Tweet-Sized Takeaways -- Chapter 8: Develop Impeccable Customer Service Skills -- Frame Customer Service as a Form of Networking -- Listen for What Is Being Said -- Listen for What Is Not Being Said -- Ask Questions From a Place of Curiosity -- Mirror Back What You Observe -- Make People Feel Validated -- Let Everyone Get What They Need -- Show Them How to "Hold the Beach Ball" -- Give Authority to Make Low-Level Decisions -- Administer Trial Runs -- Tweet-Sized Takeaways…”
Libro electrónico -
13693por International Society on Oxygen Transport to TissueTabla de Contenidos: “….- Kidney Function after In Vivo Gene Silencing of Uncoupling Protein-2 in Streptozotocin-induced Diabetic Rats.- Adenosine A2 Receptor-mediated Regulation of Renal Hemodynamics and Glomerular Filtration Rate is Abolished in Diabetes.- Can Mitochondrial Cytochrome Oxidase Mediate Hypoxic Vasodilation via Nitric Oxide Metabolism?.…”
Publicado 2012
Libro electrónico -
13694Publicado 2018Tabla de Contenidos: “…Aczel ; Turning students into citizen scientists / John Harlin, Laure Kloetzer, Dan Patton, Chris Leonhard and Leysin American School high school students ; Citizen science and the role of natural history museums / Andrea Sforzi, John Tweddle, Johannes Vogel, Grégoire Lois, Wolfgang Wägele, Poppy Lakeman-Fraser, Zen Makuch and Katrin Vohland ; Stories can change the world : citizen science communication in practice / Susanne Hecker, Monique Luckas, Miriam Brandt, Heidy Kikillus, Ilona Marenbach, Bernard Schiele, Andrea Sieber, Arnold J.H. van Vliet, Ulrich Walz and Wolfgang Wende -- Conclusions. Citizen science to foster innovation in open science, society and policy / Aletta Bonn, Susanne Hecker, Anne Bowser, Zen Makuch, Johannes Vogel and Muki Haklay…”
Libro electrónico -
13695Publicado 2016Tabla de Contenidos: “…(Van Eyken)* -- Ik misse u -- I Miss You (Vincent)* -- Een dreupel poesij -- A Drop of Poetry (King)* -- God is daar -- God is There (Van Eyken)* -- Als de ziele luistert -- When the Soul Listens (Swepstone) -- Ter inleidinge -- Introduction (Vincent)* -- Kerkhofblommen -- Churchyard Flowers (fragment, Van Eyken)* -- Gij badt op eenen berg -- You Prayed on the Mountainside, Alone (Brockway) -- 1866 -- Heidensch lied -- Pagan Song (Van Eyken) -- 1870 -- Halleluja -- Hallelujah (Van Eyken)* -- 1872 -- Verloren moeite -- Wasted Effort (Van Eyken) -- 1877 -- O dichtergeest -- O Poetry (Vincent)* -- En durft gij mij -- And Do You Dare (Vincent)* -- 1879 -- De Vlaamsche taal -- Our Flemish Speech (Barnouw) -- 1880 -- O vrienden -- O Friends (Van Eyken) -- 1882 -- O wilde en overvalschte pracht -- O Wild and Perfect Harmony (Van Eyken)* -- Wat hangt gij daar te praten -- What Is It Then Attracts Thee (Swepstone) -- 1883 -- Mijn hert is als een blomgewas -- My Heart Is Like a Tender Flower (Swepstone) -- 1886 -- Drie dingen -- Three Burdens (Van Eyken)* -- 1888 -- De nachtegalen klinken -- The Nightingales Are Calling (Hare) -- 1890 -- O blomme -- O Flower (Van Eyken)* -- 1891 -- Moederken -- Little Mother (Swepstone)* -- Zonnewende -- Sunspurge (Lovelock)* -- 1892 -- Verloren is 't gepijnd -- We Strive in Vain (Van Eyken)* -- 1893 -- Fiat Lux -- Fiat Lux (Van Eyken)* -- 't Avondt, 't Avondt; traag en treurig -- Evening Slowly Veils the Skies (Van Eyken) -- Naar het kribbeken des heeren -- The Crib (Van Eyken)* -- De ramen -- Church Window (Van Eyken) -- O leeksken licht -- O Leak of Light (Claes/D'haen) -- 'k En ete niet, of 't gene ik ete -- I Never Eat but What I Eat (Claes/D'haen) -- 1894 -- Den ouden brevier -- The Old Breviary (Vincent)* -- Hoe zeere vallen ze af -- How Soon They All Drop Down (Vincent)* -- 1895 -- Slapende botten -- Sleeping Buds (Claes/D'haen) -- 1896 -- Casselkoeien -- The Cassel Cows (Swepstone) -- Hier ben ik -- Here Am I (Van Eyken)* -- Wintermuggen -- Winter Midges (Claes/D'haen) -- Tranen -- Tears (Claes/D'haen) -- 1897 -- Jam Sol Recedit -- Iam sol recedit (Claes/D'haen) -- Twee horsen -- Twa Aivers (Lovelock)* -- Bonte abeelen -- The Aspen Tree (Bithell) -- Winterstilte -- Winter Quiet (Bithell) -- Gierzwaluwen (Cypselus Apus) -- Swifts (Cypselus Apus) -- Op krukken -- Yearning (Van Eyken) -- Juvabit! …”
Libro electrónico -
13696Publicado 2024“…Uncovering the links between our genetic makeup, environment and experiences, this is an important contribution to ongoing debates on ethics, genetics and responsibility…”
Libro electrónico -
13697por Organisation de coopération et de développement économiques.“…Suite à la décision du Conseil de l’OCDE, l’essai 480 " Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay " a été supprimé le 2 avril 2014. …”
Publicado 1986
Libro electrónico -
13698Publicado 2016“…Also of importance is the pollution of aquatic environments with antibiotics, resistance genes and the mobile genetic elements that house resistance genes from human and animal waste. …”
Libro electrónico -
13699
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13700