Tabla de Contenidos: “…About the Special Issue Editors -- Preface to "Chemically-Induced DNA Damage, Mutagenesis, and Cancer" -- DNA Damage, Mutagenesis and Cancer -- The Future of DNA Adductomic Analysis -- Every OGT Is Illuminated ... by Fluorescent and Synchrotron Lights -- Enhanced Susceptibility of Ogg1 Mutant Mice to Multiorgan Carcinogenesis -- DNA Damage Tolerance by Eukaryotic DNA Polymerase and Primase PrimPol -- Exposure to Engineered Nanomaterials: Impact on DNA Repair Pathways -- Magnetic Hyperthermia and Oxidative Damage to DNA of Human Hepatocarcinoma Cells -- The Role of Resveratrol in Cancer Therapy -- Supercritical-Carbon Dioxide Fluid Extract from Chrysanthemum indicum Enhances Anti-Tumor Effect and Reduces Toxicity of Bleomycin in Tumor-Bearing Mice -- Significance of Wild-Type p53 Signaling in Suppressing Apoptosis in Response to Chemical Genotoxic Agents: Impact on Chemotherapy Outcome -- A Case-Control Study of the Genetic Variability in Reactive Oxygen Species-Metabolizing Enzymes in Melanoma Risk -- CoQ10 Deficiency May Indicate Mitochondrial Dysfunction in Cr(VI) Toxicity -- The Effect of VPA on Increasing Radiosensitivity in Osteosarcoma Cells and Primary-Culture Cells from Chemical Carcinogen-Induced Breast Cancer in Rats -- High NOTCH1 mRNA Expression Is Associated with Better Survival in HNSCC -- Dynamic Reorganization of the Cytoskeleton during Apoptosis: The Two Coffins Hypothesis…”

Tabla de Contenidos: “…Manikandan, C.V. Rahav -- Genetic Algorithm Based Feature Selection And Random Forest Model For Rice Yield Prediction / Dr. …”

Tabla de Contenidos: “…Ecosystem Health and Human Impacts -- Appendix: A Primer on Population Genetics -- Appendix: Instantaneous and Finite Rates -- Appendix: Species Diversity Measures of Heterogeneity -- Bibliography -- Index -- 3.…”

Tabla de Contenidos: “…Using Performance Monitoring to Improve Community Health: Conceptual Framework and Community Experience -- Copyright -- Contents -- Using Performance Monitoring to Improve Community Health: Conceptual Framework and Community Experience -- INTRODUCTION -- The Committee's Charge -- The Workshop -- BACKGROUND1 -- DETERMINANTS OF HEALTH4 -- Health Field Model -- Social Environment -- Genetic Endowment -- Physical Environment -- Behavior -- Health Care -- Linking the Determinants -- INTERVENTIONS TO IMPROVE HEALTH -- Community Interventions -- Targets for Intervention -- Implications for Performance Monitoring -- COMMUNITY EXPERIENCE WITH PERFORMANCE MONITORING -- McHenry County Project for Local Assessment of Need6 -- City of Escondido Health Care and Community Services Project7 -- North Shore Community Health Network Area8 -- Arizona Partnership for Infant Immunization9 -- Calhoun County Health Improvement Program11 -- DISCUSSION -- Identification of Stakeholders -- Selecting Health Issues and Performance Indicators -- Should Performance Indicators Be Standardized? …”

Tabla de Contenidos: “….] -- Molecular characterization of genetic diversity among arbuscular mycorrhizal fungi / M. …”

Tabla de Contenidos: “…. -- v.XIV : ERYS-FL. -- v.XV : FOET-GÈNÉR. -- v.XVI : GEN-GRIP. -- v.XVII : GROS-HU. -- v.XVIII : HYD-INFL. -- v.XIX : INFUS-KYST. -- v.XX : LAC-LUX. -- v.XXI : LYC-MÉC. -- v.XXII : MÉD-MOEL. -- v.XXIII : MOL-NÈV. -- v.XXIV : NEZ-ORC. -- v.XXV : ORE-PAP. -- v.XXVII : PESS-PIG. -- v.XXVIII : PIL-POI. -- v.XXIX : POL-PRO. -- v.XXX : PS-REI. -- v.XXXI : REI-ROT. -- v.XXXII : ROU-SCR. -- v.XXXIII : SE-ST. -- v.XXXIV : SU-SY. -- v.XXXV : TA-TO. -- v.XXXVI : TR-TYPHO. -- v.XXXVII : TYP-UTÉR. -- v.XXXVIII : VAC-VEI. -- v.XXXIX : VEN-ZO. -- v.XL : ZYN…”

Tabla de Contenidos: “…Pedestrian Performance Data -- Federal Investigation of the Evacuation of the World Trade Center on September 11, 2001 -- Free speed distributions — Based on empirical data in different traffic conditions -- Collecting Pedestrian Trajectory Data In Real-time -- Full-Scale Evacuation Experiments in a smoke filled Rail Carriage — a detailed study of passenger behaviour under reduced visibility -- Minimum Stair Width for Evacuation, Overtaking Movement and Counterflow — Technical Bases and Suggestions for the Past, Present and Future -- Study on information guiding based on human psych-physiological responses in China -- Research on pedestrian crowd characteristics and behaviours in peak-time on Chinese campus -- Pedestrian Dynamics -- Behaviour on tunnel fire -- Earthquake — the importance of earthquake-resistant design in case of emergency evacuations -- Decision Loads and Route Qualities for Pedestrians — Key Requirements for the Design of Pedestrian Navigation Services -- Cyclone and Storm Surge, Pedestrian Evacuation and Emergency Response in India -- Experimental Study and Theoretical Analysis of Signage Legibility Distances as a Function of Observation Angle -- Exploring Pedestrian Shopping Decision Processes — an Application of Gene Expression Programming -- Evacuation Simulation -- A Discrete choice framework for acceleration and direction change behaviors in walking pedestrians -- Calibration and validation of the Legion simulation model using empirical data -- Evacuation Simulation for Road Tunnels — Findings from the use of microscopic methodology for escape route analyses -- A Data-Driven Model of Pedestrian Movement -- Distributed intelligence in pedestrian simulations -- Design of Escape Routes by Simulating Evacuation Dynamics in Conjunction with a Probabilistic Safety Concept -- The 2001 World Trade Centre Evacuation -- Dynamic Navigation Field — a local and on-demand family of algorithms for wayfinding -- Microscopic calibration and validation of pedestrian models — Cross-comparison of models using experimental data -- Pedestrian flow optimization with a genetic algorithm based on Boolean grids -- Developing a Pedestrian Agent Model for Analyzing an Overpass accident -- The simulation of crowd dynamics at very large events — Calibration, empirical data, and validation -- Moore and more and symmetry -- The RiMEA Project — Development of a new Regulation -- Football Stadium Simulation — A microscopic simulation of the pedestrian access -- Instability of pedestrian flow in two-dimensional optimal velocity model -- Evacuation Simulation at Linz Central Station — Usefulness during design, approval and start-up -- Why “Faster is Slower” in Evacuation Process -- Development of an Agent-based Behavior Module for Evacuation Models — Focused on the Behaviors in the Dark -- Comparative Investigation of the Dynamic Simulation of Foot Traffic Flow -- Evacuation from underground railway stations — Available and required safe egress time for different station types and general evaluation criteria -- A discrete microscopic model for pedestrian dynamics to manage emergency situations in airport terminals -- Steps Toward the Fundamental Diagram — Empirical Results and Modelling -- Model for Office Building Usage Simulation -- Features of Discrete Event Simulation Systems for Spatial Pedestrian and Evacuation Dynamics -- Evolving Direct Perception Models of Human Behavior in Building Systems -- Fundamental diagram of a one-dimensional cellular automaton model for pedestrian flow — the ASEP with shuffled update -- Ship Evacuation -- Implementing Ship Motion in AENEAS — Model Development and First Results -- Data Collection in Support of the Modelling of Naval Vessels -- Collective animal motion -- Self-organised choice based on inter-attraction: the example of gregarious animals -- Traffic on bi-directional ant-trails -- Herding in Real Escape Panic -- From Ant Trails to Pedestrian Dynamics — Learning from Nature…”

Tabla de Contenidos: “…Incoming news on the F-type ATPase structure and functions in mammalian mitochondria -- The antimicrobial peptide Polybia-MP1 differentiates membranes with the hopanoid, diplopterol from those with cholesterol -- Probucol treatment is associated with an ABCA1-independent mechanism of cholesterol efflux to lipid poor apolipoproteins from foam cell macrophages -- Changes in neurodegeneration-related miRNAs in brains from CAPN1−/− mice -- Origin of the Phosphoprotein Phosphatase (PPP) sequence family in Bacteria: Critical ancestral sequence changes, radiation patterns and substrate binding features -- Role of the Connexin C-terminus in skin pattern formation of Zebrafish -- Effects of CpG methylation on the thermal stability of c-kit2, c-kit*, and c-kit1 G-quadruplex structures -- Narciclasine is a novel YAP inhibitor that disturbs interaction between YAP and TEAD4 -- The 1.3-Å resolution structure of bovine cytochrome c oxidase suggests a dimerization mechanism -- Investigating the lipid fingerprint of SLC6 neurotransmitter transporters: a comparison of dDAT, hDAT, hSERT, and GlyT2 -- A native cell membrane nanoparticles system allows for high-quality functional proteoliposome reconstitution -- Modeling of Ca2+ transients initiated by GPCR agonists in mesenchymal stromal cells -- Urinary exosome proteomic profiling defines stage-specific rapid progression of autosomal dominant polycystic kidney disease and tolvaptan efficacy -- Kinetic modeling of substrate-water exchange in Photosystem II -- Lipid and protein dynamics of stacked and cation-depletion induced unstacked thylakoid membranes -- Asymmetric dynamics of dimeric SARS-CoV-2 and SARS-CoV main proteases in an apo form: Molecular dynamics study on fluctuations of active site, catalytic dyad, and hydration water -- Effect of quercetin on lipid membrane rigidity: assessment by atomic force microscopy and molecular dynamics simulations -- Quantitative assessment of chlorophyll types in cryo-EM maps of photosystem I acclimated to far-red light -- Fragments of Locusta migratoria apoLp-III provide insight into lipid binding -- The degree and position of phosphorylation determine the impact of toxic and trace metals on phosphoinositide containing model membranes -- Kinetic analysis of antibody binding to integral membrane proteins stabilized in SMALPs -- Inhibition of selenoprotein synthesis by Zika virus may contribute to congenital Zika syndrome and microcephaly by mimicking SELENOP knockout and the genetic disease PCCA -- Membrane dynamics are slowed for Alexa594-labeled membrane proteins due to substrate interactions -- Analysis of the assembly pathway for membrane subunits of Complex I reveals that subunit L (ND5) can assemble last in E. coli -- The balance of concentration between Prokineticin 2β and Prokineticin 2 modulates the food intake by STAT3 signaling -- Identification and characterization of the Hfq bacterial amyloid region DNA interactions -- Leading individual features of antioxidant systematically classified by the ORAC assay and its single electron transfer and hydrogen atom transfer reactivities; analyzing ALS therapeutic drug Edaravone -- Epigenetic modulation of selected immune response genes and altered functions of T lymphocytes and macrophages collectively contribute to autoimmune diabetes protection -- A theoretical perspective of the physical properties of different RNA modifications with respect to RNA duplexes -- Corrigendum to Quantitative assessment of chlorophyll types in cryo-EM maps of photosystem I acclimated to far-red light BBA Advances 1 (2021) 100019.…”

Tabla de Contenidos: “…Oral Contraceptives &amp -- Breast Cancer -- Copyright -- Preface -- Contents -- Executive Summary -- MAINTAINING SURVEILLANCE -- DEVELOPING A BROADER ARRAY OF CONTRACEPTIVES -- ASSESSING KNOWLEDGE FOR APPLICATION IN CLINICAL PRACTICE -- FILLING GAPS IN BIOLOGICAL AND EPIDEMIOLOGICAL KNOWLEDGE -- 1 Introduction and Overview -- BIOLOGICAL PLAUSIBILITY OF A LINK BETWEEN ORAL CONTRACEPTIVES AND BREAST CANCER -- WHAT IS-AND IS NOT-KNOWN -- SEEKING ANSWERS -- 2 Epidemiology: Information Needs and Data Gaps -- EPIDEMIOLOGICAL RESEARCH -- Case-Control Method -- Cohort Studies -- Comparison Groups -- Ecological Studies -- Special Studies -- Women Exposed to Hormones Other than Oral Contraceptives -- Women Genetically Susceptible to Breast Cancer -- Estrogen Metabolism -- Progestins -- Changing Oral Contraceptive Formulations -- SUMMARY AND CONCLUSIONS -- 3 Biology: Information Needs and Data Gaps -- SIGNAL COMPLEXITY IN BREAST REGULATION -- RESEARCH ISSUES -- Relationships Among Cell Types -- Receptors -- Timing -- Effects of Pregnancy and Lactation -- Pathological Breast Tissue -- Oncogenes -- Molecular Changes Associated with Human Breast Cancer -- Activated ras Mutations -- Overexpression of Tyrosine Kinases -- Amplification of int-2 and myc -- Deletions of Genes -- RESEARCH MODELS -- Breast Cancer Cell Lines -- Short-term Culture of Normal Mammary Epithelium -- Organ Culture -- Nude Mouse Model -- SUMMARY AND CONCLUSIONS -- 4 Information for Users of the Pill and Health Care Providers -- BENEFITS AND RISKS OF ORAL CONTRACEPTIVES -- Benefits -- Risks -- CURRENT CONTROVERSY -- PRESCRIBING PROBLEMS -- 5 Policy Issues and Recommendations -- MAINTAINING SURVEILLANCE -- Cooperative Research -- Surveillance Requirements of the Food and Drug Administration -- DEVELOPING A BROADER ARRAY OF CONTRACEPTIVES…”

Tabla de Contenidos: “…71 Kommunale Kulturpolitik und deutsche Einheit 77 Potenziale des Möglichen in Magdeburg 85 Kulturpolitik nach der Wiedervereinigung - Neuausrichtung und beständige Weiterentwicklung 89 Soviel Anfang war nie - Kulturpolitik nach der »Wende« 97 Kulturpolitik nach der »Wende« - Verständnis und Missverständnisse 107 Land und Kultur erhalten? …”

Tabla de Contenidos: “…Capítulo 6 - Patrones de la organización de los genes en el ADN: anatomía molecular -- El genoma humano -- Cromosomas yregiones cromosómicas -- Polimorfismos genéticos -- Definición de las secuencias repetidas -- Definición y anatomía de un gen -- El genoma mitocondrial -- Referencias bibliográficas -- Capítulo 7 - Constancia y variación -- Introducción -- Selección natural -- Teoría neutral de la evolución molecular -- Polimorfismo genético -- Mutación y otros tipos de variaciones en el ADN -- Impacto de las mutaciones sobre el fitness (mutación y selección) -- Referencias bibliográficas -- Capítulo 8 - Familias de genes -- Introducción -- Familias de genes en humanos -- Referencias bibliográficas -- Capítulo 9 - Tipos y estructuras del ARN -- Tipos de ARN -- Referencias bibliográficas -- Capítulo 10 - ARN polimerasas,transcripción de ADN, proceso de splicing y splicing alternativo -- Introducción -- Las ARN polimerasas (ARN pol) -- Transcripción del ADN -- Modificaciones postranscripcionales -- Referencias bibliográficas -- Capítulo 11 - Control de la transcripción de genes por secuencias trans -- Definición -- Primer mecanismo de cambio epigenómico: el código histona -- Segundo mecanismo epigenético: la metilación del ADN -- Tercer mecanismo de control epigenético: los pequeños arn de interferencia -- Referencias bibliográficas -- Capítulo 12 - Del genotipo al fenotipo: síntesis de proteínas -- Introducción -- Papel del arn en la traducción de proteínas -- Ribosoma: estructura y función -- Aminoacil-arnt sintetasas -- Etapas de la síntesis de proteínas -- Referencias bibliográficas -- Capítulo 13 - Estructura de proteínas -- Reseña histórica -- Introducción a la estructura de proteínas -- Los aminoácidos: base de las proteínas -- Estructura de las proteínas -- Referencias bibliográficas -- Capítulo 14 - Plegamiento y modificación de proteínas…”

Tabla de Contenidos: “…Introduction -- 01 Upcycling into Art -- Andy Barrett: Carton Marquetry -- Cardboard Box Office: The Family Movie Life -- James Grashow: Cardboard Till Death -- 02 Redefining the Everyday -- Chris Gilmour: Cultural Weight and Cardboard -- Don Lucho/Luis Valdes: El Puesto de Don Lucho -- Evol: Visions of the Working Class -- Kiel Johnson: The City and the Lens -- 03 From Mundane to Luxurious -- Ann Weber: Woven -- Jillian Salik: Becoming Baroque -- Jözef Sumichrast: As Fine as Velvet -- Lacy Barry: Trompe L'Oeil Luxury -- 04 Larger than Life -- Joseph DeLappe: From Second Life to Three Dimensions -- Laurence Vallières: Monkeying Around -- Mykl Wells: The Wow Factor -- Taro Hattori: Cardboard and Conceptual Lightness -- 05 Sweet Sweet Fantasy -- Dosshaus: A Beautiful World in Black and White -- Muffinhead: The Living Sculpture -- Wayne White: Puppet Land -- 06 The Technical and the Abstract -- Daniel Agdag: Industrial Imaginings Under the Bell Jar -- Maika'i Tubbs: Pulp Fiction -- Mark Langan: Delicate Corrugation -- 07 Diys by Artists -- Sailing Ship: Beau Stanton -- Geometric Wall Storage: Ian Kuali'i -- Stacked Table: James Heffron -- Polygon Sculpture: Jud Bergeron -- Cardboard Balloon with Bow: Lacy Barry -- Stenciled Wrapping Paper: Logan Hicks -- Pineapple Grenade: James Cerasani -- Cardboard Fish: Rebecca Paul and Jeronimo Zancaner -- Multi-Use Geodesic Dome: Robin Redd -- Index -- About the Author -- Acknowledgments -- Also Available -- Dedication -- Copyright…”

Tabla de Contenidos: “…Introduction and History of the Chemistry of Nucleic Acids Therapeutics -- Antisense RNA Therapeutics: A Brief Overview -- Design of Bifunctional Antisense Oligonucleotides for Exon Inclusion -- Design and Delivery of SINEUP: A New Modular Tool to Increase Protein Translation -- How to Design U1 snRNA Molecules for Splicing Rescue -- Conjugation of Nucleic Acids and Drugs to Gold Nanoparticles -- Determination of Optimum Ratio of Cationic Polymers and Small Interfering RNA with Agarose Gel Retardation Assay -- Generation of Protein-Phosphorodiamidate Morpholino Oligomer Conjugates for Efficient Cellular Delivery via Anthrax Protective Antigen -- Development and Use of Cellular Systems to Assess and Correct Splicing Defects -- Modeling Splicing Variants Amenable to Antisense Therapy by Use of CRISPR-Cas9-Based Gene Editing in HepG2 Cells -- In Vitro Models for the Evaluation of Antisense Oligonucleotides in Skin -- In Vitro Delivery of PMOs in Myoblasts by Electroporation -- Rapid Determination of MBNL1 Protein Levels by Quantitative Dot Blot for Evaluation of Antisense Oligonucleotides in Myotonic Dystrophy Myoblasts -- Evaluation of Exon Skipping and Dystrophin Restoration in In Vitro Models of Duchenne Muscular Dystrophy -- Generation of Human iPSC-Derived Myotubes to Investigate RNA-Based Therapies In Vitro -- Eye on a Dish Models to Evaluate Splicing Modulation -- Establishment of In Vitro Brain Models for AON Delivery -- Considerations for Generating Humanized Mouse Models to Test Efficacy of Antisense Oligonucleotides -- Generation of Humanized Zebrafish Models for the In Vivo Assessment of Antisense Oligonucleotide-Based Splice Modulation Therapies -- Use of Small Animal Models for Duchenne and Parameters to Assess Efficiency upon Antisense Treatment -- In Vivo Models for the Evaluation of Antisense Oligonucleotides in Skin -- Delivery of Antisense Oligonucleotides to the Mouse Retina -- Delivery of Antisense Oligonucleotides to the Mouse Brain by Intracerebroventricular Injections -- Intrathecal Delivery of Therapeutic Oligonucleotides for Potent Modulation of Gene Expression in the Central Nervous System -- Preclinical Safety Assessment of Therapeutic Oligonucleotides -- Preclinical Evaluation of the Renal Toxicity of Oligonucleotide Therapeutics in Mice -- Protocol for Isolation and Culture of Mouse Hepatocytes (HCs), Kupffer Cells (KCs), and Liver Sinusoidal Endothelial Cells (LSECs) in Analyses of Hepatic Drug Distribution -- Patent Considerations When Embarking on New Antisense Drug Programs…”

Tabla de Contenidos: “…Lewontin -- The return of the gene / Kim Sterelny and Philip Kitcher -- The levels of selection debate : philosophical issues / Samir Okasha -- Sociobiology and ethics -- Sociobiology : the new synthesis / Edward O. …”

Tabla de Contenidos: “…-- Kinetics and Signal Activation Properties of Circulating Factor(s) From Healthy Volunteers Undergoing Remote Ischemic Pre-Conditioning -- Cardiosphere-Derived Cells Reverse Heart Failure With Preserved Ejection Fraction in Rats by Decreasing Fibrosis and Inflammation -- Extracellular Matrix Hydrogel Promotes Tissue Remodeling, Arteriogenesis, and Perfusion in a Rat Hindlimb Ischemia Model -- Telomerase Inhibition by Everolimus Suppresses Smooth Muscle Cell Proliferation and Neointima Formation Through Epigenetic Gene Silencing -- The Role of the L-Type Ca2+ Channel in Altered Metabolic Activity in a Murine Model of Hypertrophic CardiomyopathyCell Therapy for Heart Failure With Preserved Ejection Fraction -- Better Blood Flow Delivered: Extracellular Matrix-Derived Hydrogels for the Induction of Arteriogenesis in Peripheral Artery Disease? …”

Tabla de Contenidos: “…23 Trends und Megatrends als Ansatz der modernen Zukunftsforschung 45 Irrwege und Entwicklungspfade 61 Quid agis, Megatrend? 81 Was nützt die Wende in Gedanken? 119 Umbrüche und Verunsicherungen 167 »Einfach zu viele Autos«: Neue Antriebe alleine reichen nicht 193 Die Post-Landwirtschaftliche Revolution 215 Empowerment in Transformations-Arenen 235 Die Energiewende als Werk ausgewählter Gemeinschaften? …”

Tabla de Contenidos: “…Dixon -- A Class Act/Elvira Doman -- It's in My Genes/Georgia Dunston -- Destined to Greater Heights/Evelyn Boyd Granville -- The Sky is the Limit/Shirley Ann Jackson -- An Unlikely Scientist/Lynda M. …”

Tabla de Contenidos: “…Spanienbilder in Texten deutscher Reisender an der Wende zur Neuzeit (15J16. Jahrhundert) / Spanien in der Zeit der Habsburger Monarchie. …”

Tabla de Contenidos: “…Preface -- Something Is going on / John Aubrey Douglass -- Neo-nationalism and universities in historical perspective / John Aubrey Douglass -- Neo-nationalism and universities : a conceptual model / John Aubrey Douglass -- The mystery of Brexit : tumult and fatigue in British higher education / Brendan O'Malley -- Trumpian nationalism and American universities / John Aubrey Douglass -- Turbulent times : intellectual and institutional challenges for universities in Germany, Hungary and Poland / Wilhelm Krull and Thomas Brunotte -- Neo-nationalism and universities in Europe / Marijk van der Wende -- Turkish academics in the era of Erdoğan / Brendan O'Malley -- Nationalism revived : China's universities under president XiKarin Fischer -- Balancing nationalism and globalism : higher education in Singapore and Hong Kong / Bryan E. …”

Tabla de Contenidos: “…My honey's loving arms (Joe Venuti's Blue Four)--Rocky Mountain blues (Harlem Footwarmers)--Hejre Kati (Eddie South and his international orchestra)--Sister Kate (Henry Allen and Coleman Hawkins and their orchestra)--China boy (Candy and Coco)--Square face (Gene Gifford and his orchestra)--I got rhythm (Red Norvo and his swing sextet)--Chasing shadows (Putney Dandridge and his orchestra)--Knock, knock (Stuff Smith and his Onyx Club Orchestra)--In a little gypsy tearoom (Louis Prima and his New Orleans Gang)--Bugle call rag (Roly's Tap-Room Gang)--Jungle love (Teddy Wilson and his orchestra)--What's the use? …”