“…These articles are based on or related to the topics of the 3rd International Conference «Genetics of aging and longevity». The Conference took place 6-10 April, 2014 in Sochi, the city located on the Black Sea coast near the Caucasian mountains, in Russia. …”

Materias:

Tabla de Contenidos: “…Editorial: application of genetically encoded indicators to mammalian central nervous system --Monitoring activity in neural circuits with genetically encoded indicators --Putting a finishing touch on GECIs --Genetically encoded Ca2+ indicators; expanded affinity range, color hue and compatibility with optogenetics --Investigating neuronal function with optically controllable proteins --Exploration of genetically encoded voltage indicators based on a chimeric voltage sensing domain --Engineering a genetically-encoded SHG chromophore by electrostatic targeting to the membrane --Imaging activity in astrocytes and neurones with genetically encoded calcium indicators following in utero electroporation --Intracellular calcium dynamics in cortical microglia responding to focal laser injury in the PC::G5-tdT reporter mouse --Wide-field Ca2+ imaging reveals visually evoked activity in the retrosplenial area --Habituation of glomerular responses in the olfactory bulb following prolonged odor stimulation reflects reduced peripheral input…”

“…More generally, research on single gene defects and their role in disease, as well as recent large scale sequencing studies suggest that a large number of genetic variations may contribute to disease not only by affecting gene function or expression but also by modulating complex protein interaction networks.The aim of this research topic is to bring together researchers working in the area of drug, steroid and xenobiotic metabolism who are studying protein-protein interactions, to describe their recent advances in the field. …”

“…Dominant lethals are generally accepted to be the result of chromosomal aberrations (structural and numerical anomalies), but gene mutations and toxic effects cannot be excluded. …”

“…GECCO '10 Genetic and Evolutionary Computation Conference, Portland, OR, USA - July 07 - 11, 2010…”

“…It is our great pleasure to welcome you to the 4th International Genetic Improvement Workshop (GI 2018), held at ICSE 2018 on 2 June 2018 in Gothenburg, Sweden. …”