Materias: “…Medical genetics…”

Materias: “…Genomes Congresses…”

Materias: “…Human genome…”

Materias: “…Medical genetics…”

Materias: “…Medical genetics…”

Materias: “…Microbial genomics…”

Tabla de Contenidos: “…List of Contributors -- About the Guest Editor -- Preface -- Chapter 1: Neuronal -- Opportunities and Limitations of Modelling Alzheimer's Disease with Induced Pluripotent Stem Cells -- Induced Pluripotent Stem Cells Derived from Alzheimer's Disease Patients: The Promise, the Hope and the Path Ahead -- iPSC-based Models to Unravel Key Pathogenetic Processes underlying Motor Neuron Diseases Development -- Chapter 2: Cardiac -- Bioengineering and Stem Cell Technology in the Treatment of Congenital Heart Disease -- Scalable Electrophysiological Investigation of iPS Cell Derived Cardiomyocytes Obtained by a Lentiviral Purification Strategy -- Clinical Potentials of Cardiomyocytes Derived from Patient-Specific Induced Pluripotent Stem Cells -- Chapter 3: Eye -- iPS Cells for Modelling and Treatment of Retinal Diseases -- Patient-Specific iPSC-Derived RPE for Modeling of Retinal Diseases -- Potential role of Induced Pluripotent Stem Cells (IPSCs) for Cell-Based Therapy of the Ocular Surface -- Chapter 4: Spinal Cord Injury -- The Potential for iPS-Derived Stem Cells as a Therapeutic Strategy for Spinal Cord Injury: Opportunities and Challenges -- The State of Play with iPSCs and Spinal Cord Injury Models -- Chapter 5: Liver -- Potential and Challenges of Induced Pluripotent Stem Cells in Liver Diseases Treatment -- Chapter 6: Muscle -- Myogenic Precursors from iPS Cells for Skeletal Muscle Cell Replacement Therapy -- Chapter 7: Bone -- The Use of Patient-Specific Induced Pluripotent Stem Cells (iPSCs) to Identify Osteoclast Defects in Rare Genetic Bone Disorders -- Chapter 8: Germ Cells -- Human iPS Cell-derived Germ Cells: Current Status and Clinical Potential -- Chapter 9: Genetic Disorders -- Comparing ESC and iPSC-Based Models for Human Genetic Disorders -- Design of a Tumorigenicity Test for Induced Pluripotent Stem Cell (iPSC)-Derived Cell Products -- Concise Review: Methods and Cell Types Used to Generate Down Syndrome Induced Pluripotent Stem Cells -- Chapter 10: Immune Response -- The Possible Future Roles for iPSC-Derived Therapy for Autoimmune Diseases…”

Tabla de Contenidos: “…Preface -- Section 1 Introduction -- Chapter 1 Introductory Chapter: CRISPR Technology by Yuan-Chuan Chen -- Chapter 2 Emerging CRISPR Technologies by Annelise Cassidy and Stephane Pelletier -- Section 2 Technology -- Chapter 3 Maximizing the Efficacy of CRISPR/Cas Homology-Directed Repair Gene Targeting by Terry S. Elton, Md. Ismail Hossain, Jessika Carvajal-Moreno, Xinyi Wang, Dalton J. …”

Materias: “…Medical genetics…”

Materias: “…Genetic regulation…”

Materias: “…Genetics…”

Materias: “…Medical genetics…”

Tabla de Contenidos: “…. -- Recommendation for Research on Juror Comprehension -- Overview -- INTRODUCTION -- OUR ASSIGNMENT -- DNA TYPING -- BASIC GENETIC PRINCIPLES -- FORENSIC DNA IDENTIFICATION -- VNTRs -- DNA Profiling -- Matching and Binning of VNTRs -- Allele (Bin) Frequencies -- PCR-Based Systems -- ASSURING LABORATORY ACCURACY -- POPULATION GENETICS -- Randomly Mating Populations -- Population Structure -- Dealing with Subpopulations -- Persons from the Same Subpopulation -- SOME STATISTICAL CONSIDERATIONS -- The Reference Database -- Match Probability, Likelihood Ratio, and Two Fallacies -- Bayes's Theorem -- Suspect Identified by Database Search -- Uniqueness -- Uncertainty About Estimated Frequencies -- PCR-Based Tests -- THE CEILING PRINCIPLES -- DNA IN THE COURTS -- CONCLUSIONS AND RECOMMENDATIONS -- Admissibility of DNA Evidence (Chapter 2) -- Laboratory Errors (Chapter 3) -- Proficiency Tests -- Duplicate Tests -- Population Genetics (Chapter 4) -- Evidence DNA and Suspect from the Same Subgroup -- Insufficient Data -- Dealing with Relatives -- Statistical Issues (Chapter 5) -- Database Searches -- Uniqueness -- Matching and Binning -- Ceiling Principles -- Further Research -- Legal Issues (Chapter 6) -- ILLUSTRATIVE EXAMPLE -- A Typical Case -- Suspect Found by Searching a Database -- Suspect and Evidence from the Same Subpopulation -- A PCR-Based System -- 1 Introduction -- THE 1992 NATIONAL RESEARCH COUNCIL REPORT -- THE COMMITTEE'S TASK -- THE VALIDITY OF DNA TYPING…”

Materias: “…Cultura genaral …”

Materias: