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7181por Leurs, KoenTabla de Contenidos: “…Photo by Yener Bayramoğlu. -- Figure 9.3. A defaced sticker on a lamppost in Kreuzberg, Berlin, 2021. …”
Publicado 2024
Libro electrónico -
7182Publicado 2023Tabla de Contenidos: “…Cover -- Title Page -- Copyright and Credits -- Dedications -- Foreword -- Contributors -- Table of Contents -- Preface -- Part 1: Introduction to Detectron2 -- Chapter 1: An Introduction to Detectron2 and Computer Vision Tasks -- Technical requirements -- Computer vision tasks -- Object detection -- Instance segmentation -- Keypoint detection -- Semantic segmentation -- Panoptic segmentation -- An introduction to Detectron2 and its architecture -- Introducing Detectron2 -- Detectron2 architecture -- Detectron2 development environments -- Cloud development environment for Detectron2 applications -- Local development environment for Detectron2 applications -- Connecting Google Colab to a local development environment -- Summary -- Chapter 2: Developing Computer Vision Applications Using Existing Detectron2 Models -- Technical requirements -- Introduction to Detectron2's Model Zoo -- Developing an object detection application -- Getting the configuration file -- Getting a predictor -- Performing inferences -- Visualizing the results -- Developing an instance segmentation application -- Selecting a configuration file -- Getting a predictor -- Performing inferences -- Visualizing the results -- Developing a keypoint detection application -- Selecting a configuration file -- Getting a predictor -- Performing inferences -- Visualizing the results -- Developing a panoptic segmentation application -- Selecting a configuration file -- Getting a predictor -- Performing inferences -- Visualizing the results -- Developing a semantic segmentation application -- Selecting a configuration file and getting a predictor -- Performing inferences -- Visualizing the results -- Putting it all together -- Getting a predictor -- Performing inferences -- Visualizing the results -- Performing a computer vision task -- Summary…”
Libro electrónico -
7183Publicado 2013Tabla de Contenidos: “…Summary -- Introduction -- 1.1 Protein aggregation and amyloidoses -- 1.1.1 Mechanisms of amyloid fibril formation -- 1.1.2 Oligomer structural polymorphism: fibrillar and prefibrillar oligomers -- 1.1.3 Oligomer toxicity: common mechanism of pathogenesis -- 1.1.4 Amyloid formation is an inherent property of polypeptide chains: functional amyloid and disease unreleated amyloid -- 1.2 HypF-N: model protein of amyloid aggregation unrelated to disease -- 1.2.1 Function, structure and aggregation of HypF-N -- 1.2.2 HypF-N protofibrils interact with cell membranes originating a cytotoxic cascade -- 1.2.3 A causative link between the structure of HypF-N oligomers and their ability to cause cellular dysfunction -- 1.3 Alzheimer's disease -- 1.3.1 The Alzheimer phenotype -- 1.3.2 The elaborate processing of APP -- 1.3.3 The genetics of Alzheimer's disease -- 1.3.4 Peripheral cells as a tool to identify and test hypotheses on AD pathophysiology -- 1.3.5 Adult neurogenesis and stem cell technology for AD -- 1.4 Cholesterol and gangliosides in the central nervous system (CNS) -- 1.4.1 Brain cholesterol metabolism -- 1.4.2 Ganglioside metabolism -- 1.4.3 Lipid rafts -- 1.4.4 Role of cholesterol in AD -- 1.4.5 Role of gangliosides in AD -- 1.5 Aim of the study -- Materials & Methods -- 2.1 Materials -- 2.1.1 Chemicals -- 2.1.2 Fluorescent probes -- 2.1.3 Peptides and aggregation protocols -- 2.2 Cell cultures -- 2.3 Methods -- 2.3.1 Separation processes -- 2.3.2 Differentiation of human mesenchymal stromal cells -- 2.3.3 Modulation of membrane cholesterol levels -- 2.3.4 Modulation of membrane GM1 levels -- 2.3.5 Cholesterol content measurements -- 2.3.6 GM1 content measurements -- 2.3.7 Cell exposure to peptide aggregates -- 2.3.8 Analysis of aggregate interaction with the cells -- 2.3.9 Analysis of aggregate interaction with GM1 -- 2.3.10 Analysis of aggregate internalisation -- 2.3.11 Analysis of membrane permeability -- 2.3.12 Analysis of cytosolic Ca2+ dyshomeostasis -- 2.3.13 Evaluation of ROS production -- 2.3.14 Analysis of lipid peroxidation -- 2.3.15 Cytotoxicity assay and cell death analysis: apoptotic and necrotic markers -- 2.3.16 Steady-state fluorescence anisotropy -- 2.3.17 Atomic force microscopy (AFM) -- 2.3.18 Measurements of the fluorescence intensities -- 2.3.19 Statistical analysis -- Results -- 3.1 Results I -- 3.1.1 A protective role for lipid raft cholesterol against amyloidinduced membrane damage in human neuroblastoma cells -- 3.1.2 Aß42 oligomer binding to the cell surface and its cytotoxic effect are modulated by membrane cholesterol content -- 3.1.3 Aß42 oligomers colocalize with lipid rafts -- 3.1.4 Isolation and characterization of DRMs -- 3.1.5 Effects of ADDLs on lipid raft structural order -- 3.1.6 AFM imaging of supported DRMs purified from cells exposed to ADDLs -- 3.2 Results II -- 3.2.1 Lipid rafts mediate amyloid-induced calcium dyshomeostasis and oxidative stress in Alzheimer's disease -- 3.2.2 Lipid rafts are primary interaction sites for Aß42 oligomers at the plasma membrane -- 3.2.3 Cholesterol and GM1 mediate Aß42 accumulation at the plasma membrane -- 3.2.4 Cholesterol and GM1 mediate Ca2+ dyshomeostasis and extensive membrane permeabilization induced by Aß42 oligomers -- 3.2.5 GM1 modulates lipid peroxidation and cytotoxicity induced by Aß42 oligomers -- 3.2.6 GM1 mediates Aß42-induced Ca2+ dyshomeostasis, lipid peroxidation and cytotoxicity in rat cortical neurons -- 3.3 Results III -- 3.3.1 Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers -- 3.3.2 Membrane cholesterol content modulates oligomer cytotoxicity -- 3.3.3 Membrane cholesterol modulates oligomer-induced alteration of intracellular Ca2+ homeostasis and ROS levels -- 3.3.4 Cholesterol levels modulate membrane permeability to the oligomers -- 3.3.5 Membrane GM1 affects the cytotoxic and permeabilizing effects of HypF-N oligomers -- 3.3.6 GM1, rather than cholesterol, plays a dominant role in oligomer cytotoxicity and membrane permeability -- 3.4 Results IV -- 3.4.1 Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aß42 aggregate toxicity -- 3.4.2 Neuronal differentiation of hMSCs results in reduced levels of membrane GM1 -- 3.4.3 Neuronal differentiation of hMSCs reduces the interaction of Aß42 oligomers with the cell surface -- 3.4.4 Neuronal differentiation of hMSCs reduces Aß42 oligomerinduced intracellular Ca2+ dyshomeostasis and oxidative stress -- 3.4.5 Neuronal differentiation of hMSCs increases cell resistance to Aß42 aggregates Discussion -- 4.1 A protective role for lipid raft cholesterol against amyloid-induced membrane damage in human neuroblastoma cells -- 4.2 Lipid rafts mediate amyloid-induced calcium dyshomeostasis and membrane permeabilization in Alzheimer's fibroblasts -- 4.3 Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers -- 4.4 Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aß42 aggregate toxicity -- 4.5 Concluding remarks -- Abbreviations -- References…”
Libro electrónico -
7184
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7185Publicado 1947Tabla de Contenidos: “…Una inscripció de Sant Joan de la Penya / per Miquel Dolç. Permanence de la peinture de style gothique français en Catalogne et Languedoc, dans la seconde moitié du XIVe siècle / per Marcel Durliat. …”
Libro -
7186Publicado 1947Tabla de Contenidos: “…Una inscripció de Sant Joan de la Penya / per Miquel Dolç. Permanence de la peinture de style gothique français en Catalogne et Languedoc, dans la seconde moitié du XIVe siècle / per Marcel Durliat. …”
991004128899706719 -
7187Publicado 2024Tabla de Contenidos: “…Cover -- Title page -- Copyright and Credits -- Contributors -- Table of Contents -- Preface -- Part 1: Recent Developments in the Field, Installations, and Hello World Applications -- Chapter 1: From Bag-of-Words to the Transformers -- Evolution of NLP approaches -- Recalling traditional NLP approaches -- Language modeling and generation -- Leveraging DL -- Considering the word order with RNN models -- LSTMs and gated recurrent units -- Contextual word embeddings and TL -- Overview of the Transformer architecture -- Attention mechanism -- Multi-head attention mechanisms -- Using TL with Transformers -- Multimodal learning -- Summary -- References -- Chapter 2: A Hands-On Introduction to the Subject -- Technical requirements -- Installing transformer with Anaconda -- Installation on Linux -- Installation on Windows -- Installation on macOS -- Installing TensorFlow, PyTorch, and Transformer -- Installing and using Google Colab -- Working with language models and tokenizers -- Working with community-provided models -- Working with multimodal transformers -- Working with benchmarks and datasets -- Important benchmarks -- GLUE benchmark -- SuperGLUE benchmark -- XTREME benchmark -- XGLUE benchmark -- SQuAD benchmark -- Accessing the datasets with an application programming interface -- Data manipulation using the datasets library -- Sorting, indexing, and shuffling -- Caching and reusability -- Dataset filter and map function -- Processing data with the map function -- Working with local files -- Preparing a dataset for model training -- Benchmarking for speed and memory -- Summary -- Part 2: Transformer Models: From Autoencoders to Autoregressive Models -- Chapter 3: Autoencoding Language Models -- Technical requirements -- BERT - one of the autoencoding language models -- BERT language model pretraining tasks…”
Libro electrónico -
7188Publicado 2010Biblioteca Universitat Ramon Llull (Otras Fuentes: Biblioteca de la Universidad Pontificia de Salamanca, Universidad Loyola - Universidad Loyola Granada)Libro electrónico
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7189
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7190
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7191
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7192
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7193Publicado 2022Tabla de Contenidos: “…Bibliografía -- Referencias bibliográficas básicas -- Referencias bibliográficas citadas -- 2 Morfología, David Serrano-Dolader y Bárbara Marqueta -- 2.1. Introducción -- 2.2. …”
Biblioteca Universitat Ramon Llull (Otras Fuentes: Biblioteca de la Universidad Pontificia de Salamanca, Universidad Loyola - Universidad Loyola Granada)Libro electrónico -
7194Publicado 2022Tabla de Contenidos: “…Artificial intelligence (AI) as a solace to help mankind out…”
Libro electrónico -
7195
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7196Publicado 2019Tabla de Contenidos: “…-- 3.4.2 CONCEPTOS FUNDAMENTALES DE LA FILOSOFÍA BUDISTA -- EVALUACIÓN -- 3.5 REPERCUSIONES DEL BUDISMO EN EL MUNDO ACTUAL -- 3.5.1 ¿UNA ESPIRITUALIDAD INCULTURADA O UN SELFST MADE RELIGION? -- 3.5.2 EL DALAI LAMA, VÍA Y CARA DEL BUDISMO EN EL MUNDO OCCIDENTAL ACTUAL -- CONCLUSIÓN -- EVALUACIÓN -- REFERENCIAS -- CAPÍTULO 4 JUDAÍSMO -- 4.1 HISTORIA: ORIGEN Y DESARROLLO -- 4.1.1 ORIGEN -- 4.1.2 MOMENTOS CRUCIALES DEL DESARROLLO -- EVALUACIÓN -- 4.2 DOCTRINA: LA TORÁ -- 4.2.1 NATURALEZA Y CONTENIDO GENERAL DE LA TORÁ -- 4.2.2 ELEMENTOS DOCTRINALES ESPECÍFICOS DE LA TORÁ -- EVALUACIÓN -- 4.3 RITOS Y FIESTAS DEL JUDAISMO -- 4.3.1 CLASIFICACIÓN GENERAL A) FIESTAS -- 4.3.2 SHABAT, YOM KIPPUR Y PASH (PASO, PASCUA) -- 4.3.3 RITO DEL BAR MITZVAH -- EVALUACIÓN -- 4.4 REPERCUSIONES DEL JUDAÍSMO EN EL MUNDO ACTUAL…”
Biblioteca Universitat Ramon Llull (Otras Fuentes: Universidad Loyola - Universidad Loyola Granada, Biblioteca de la Universidad Pontificia de Salamanca)Libro electrónico -
7197Publicado 2023Tabla de Contenidos: “…Cover -- Title Page -- Copyright and Credits -- Foreword -- Acknowledgements -- Table of Contents -- Preface -- Part 1: I, for One, Welcome our New Quantum Overlords -- Chapter 1: Foundations of Quantum Computing -- Quantum computing: the big picture -- The basics of the quantum circuit model -- Working with one qubit and the Bloch sphere -- What is a qubit? -- Dirac notation and inner products -- One-qubit quantum gates -- The Bloch sphere and rotations -- Hello, quantum world! …”
Libro electrónico -
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