“…Most accessory proteins are pleiotropic and instrumental in the counteraction of restriction factors and proteins involved in innate immune response.Several proteins of the “intrinsic” immune system that detect the presence of the assailant and initiate a subsequent immune response, as well as restriction factors that are directly devoted to arresting the replication cycle at precise steps have been characterized. …”

“…These findings have further fueled the discussion on whether microglia has a detrimental or beneficial action (M1 or M2-associated phenotypes, respectively) in the diseased or injured CNS and, more importantly, on whether we can shift the balance to a positive outcome.Although microglia and macrophages share several common features, upon M1 and M2 polarizing conditions, they are believed to develop distinct phenotypic and functional properties which translate into different patterns of activity. …”

“…Progress in these areas of tumor immunology will greatly improve our understanding of the factors that contribute to effective DC-mediated anti-tumor immune control versus DC-associated anti-tumor immune dysfunction and subsequent tumor immune escape. …”

“…Prolonged self-regulation of brain oscillation through BCI could potentially be used as a treatment for aberrant brain connections for conditions ranging from motor deficits to Autism Spectrum Disorders (ASD).Currently, ASD is an increasingly prevalent condition in the U.S. with core deficits in imitation learning, language, empathy, theory of mind, and self-awareness . …”

“…This Topic will cover aspects of both human and animal health, with special interest on zoonoses. …”

“…We encourage original studies, perspectives and review articles that relate to any aspect of cellular stress responses, from both a molecular and clinical perspective. …”

“…Does whether there is a cost associated with behaving prosocially influence decision-making? …”

“…This solution has been widely accepted and the early/late debate has been, for the most part, set aside. However, recently, perceptual load theory has been challenged on both theoretical and methodological grounds. …”

“…Here, they bring together an outstanding group of neuroscientist and clinical investigators engaged in the study of sleep, encompassing state-of-the-art studies of sleep disorders such as sleep apnoea or REM sleep behaviour disorder, studies assessing new treatments to improve sleep quality, together with experts in various domains of cognition such as vigilance, memory and dreams, in a perspective aimed at offering the interested reader a comprehensive view of the impact of age-related changes in sleep architecture on cognition…”

“…Recent work covering a wide variety of disciplines and technologies, including dense array electroencephalography (dEEG), novel methods of analyses of both the interictal dEEG and intracranial EEG (icEEG), magnetoencephalography (MEG), high-resolution magnetic resonance imaging (MRI), functional MRI (fMRI), simultaneous fMRI-EEG, fMRI connectivity measures, simultaneous dEEG-icEEG, and techniques to coregister patient-specific MRI (including white matter pathways) and dEEG, are all examples of areas of research that have contributed to a greater understanding of potential epileptogenic regions. We asked for individuals with expertise in an area of research that expands an understanding of identifying epileptic networks to contribute to this research topic…”

“…All types of submissions are welcome, including research in patient populations, healthy human participants and animals, review articles on some empirical or theoretical aspect, and of course also critical accounts of the new field. …”

“…For example, recent neuroscientific research is discovering how neuromodulators like dopamine and noradrenaline relate not only to extrinsic rewards but also to novel and surprising events, how brain areas such as the superior colliculus and the hippocampus are involved in the perception and processing of events, novel stimuli, and novel associations of stimuli, and how violations of predictions and expectations influence learning and motivation. …”

“…In this research topic, we wish to contribute towards this understanding and ask for the submission of manuscripts focusing broadly on the neural underpinnings of vicarious experience. …”

“…Applications are ubiquitous, starting from resting state in healthy subjects to modulations of consciousness and other aspects of pathophysiology.Mutual Information-based methods have provided new insights about common-principles in brain organization, showing the existence of an active default network when the brain is at rest. …”

“…It remains unknown how tau protein can be formed filaments [e.g. paired helical filament (PHF), straight filament and twisted filament] in cells albeit in vitro studies confirmed tau self-assembly by several inducing factors. Researchers are still debating whether tau oligomerization is primary event rather than tau phosphorylation in the tau pathogenesis. …”

“…The proposed research topic will provide a comprehensive, online, open access snapshot of the current state of the art on immune system modeling and analysis.The Research Topic will be organized according to the following themes; authors will be asked to identify the most suitable theme for their paper:• Immune cell activation and signaling• Immune cell population dynamics and turnover• Lymphocyte repertoires• Lymphocyte migration and immune tissue organization• Immune responses to pathogens• Immunological diseases• Immune system aging…”

“…., when one switches attention, selectively, between the various aspects of several choice alternatives). c) Temporally extended, belief-based decisions that build on the integration of evidence, which interacts with the decision maker's belief system, towards the updating of the beliefs and the formation of judgments and preferences (as in the legal context). …”

“…Finally, suggestions are provided for the way forward, with an emphasis on need for a multidimensional approach that integrate a panel of pathobiologically diverse biomarkers with clinical variables and imaging-based assessments to improve diagnosis and classification of TBI and to develop best clinical practice guidelines…”

“…Demgegenüber wurden die transatlantischen Beziehungen durch die Annäherung der USA an die Volksrepublik China sowie Diskussionen um eine Lastenteilung innerhalb der NATO und den Zusammenbruch des Bretton-Woods-Systems vor neue Herausforderungen gestellt.Die Neuregelung der Beziehungen zu den arabischen Staaten bei gleichzeitiger Wahrung deutschlandpolitischer Interessen und ohne Gefährdung der Beziehungen zu Israel stellte einen wichtigen Aspekt der Bonner Außenpolitik dar. Die Israel-Reise Außenminister Scheels und die Wiederaufnahme diplomatischer Beziehungen zu Algerien und zum Sudan bildeten hierbei wichtige Stationen.Einen fundierten Überblick zu diesen und weiteren Themen bieten die 454 Dokumente des Jahresbandes 1971 der "Akten zur Auswärtigen Politik der Bundesrepublik Deutschland"…”

“…After a brief introduction on the beauty and perennity of Greek vases inspired by the Gómez-Moreno collection, we present the background of this unique character of the 20th century and we reconstitute his assemblage in the current collections of the Instituto Goméz-Moreno, based in the Rodíguez-Acosta Foundation, in Granada. …”