“…How can we improve clinical trial design and data analyses to maintain a robust clinical research infrastructure and to ensure validity and applicability? …”

“…Transparency was low for net prices, input costs, patent expiry dates and clinical trial results and costs. Measures to improve transparency in these areas were also identified. …”

“…A companion DVD includes the lesson and media files needed to complete the book's exercises, plus free trial Logic plug-ins from leading manufacturers…”

“…The craft of color correction can take considerable trial and error to learn, while the art of color grading takes years to perfect. …”

“…In addition, a new clinical trial was approved by the government, and resumed the porcine islet transplantation research in New Zealand two years ago…”

“…Offer access to pricing software—Three-Month Trial of LeveragePoint Software. This edition is now available with software for creating and communicating economic value estimations systematically—from LeveragePoint Innovations Inc. …”

“…Many herbal agents used in cosmetics have been selected by a process of 'trial and error' and, thus, are used on the basis of experience rather than of experimental investigation. …”

“…Based on original research, combining archives and oral testimonies, this work traces, from the first trial and error of systemic approaches in the 1960s to the turning point of sustainable development in the 2000s, the history of the department Sad - Agrarian systems and development - from INRA (now INRAE). …”

“…The lessons cover free trial sign-up, interface navigation, setting up warehouses using SQL, and creating database objects. …”

“…The National Academies Committee on Developing a Framework to Address Legal, Ethical, Regulatory, and Policy Issues for Research Specific to Pregnant and Lactating Persons held a workshop in March 2023 as part of a consensus study to discuss how institutions and organizations make risk-benefit decisions regarding the inclusion and exclusion of pregnant and lactating persons in clinical research, and the role of real and perceived liability considerations, health equity, risk management, and trial insurance in those decisions. The workshop reviewed existing approaches to manage and mitigate risks relevant to the inclusion of pregnant and lactating persons in clinical research. …”

“…To guide the choice of antidepressants, clinicians have typically taken a "trial and error" approach, informed by various clinical factors thought to be associated with variable treatment response. …”

“…"Is truth in the law just plain truth - or something sui generis? Is a trial a search for truth? Do adversarial procedures and exclusionary rules of evidence enable, or impede, the accurate determination of factual issues? …”

“…As Lieutenant General, his military campaigns were crucial to victory during the Civil War and he was instrumental in the trial and execution of the King. As Lord Protector of the Commonwealth he remains the only non-royal head of state in British history. …”
Sumario

“…Special attention is devoted to the strategic use of fictive interaction in legal argumentation, with a focus on high-profile criminal trials. Both trial lawyers and lay jurors often present material evidence or murder victims as speaking, and express emotions and intentions in conversational terms. …”

“…Yet, despite our best efforts to engineer cures, luck, trial-and-error, risk, and ingenuity are still fundamental to medical discovery. …”

“…Meanwhile, artists and public figures face trial for "inciting religious hatred". What is the proper balance between freedom and equal respect for persons? …”

Tabla de Contenidos: “…Recruitment in Multicentre Trials: Prediction and Adjustment -- Optimal Design of Pharmacokinetic Studies Described by Stochastic Differential Equations -- Comparisons of Heterogeneity: a Nonparametric Test for the Multisample Case -- On Synchronized Permutation Tests in Two-Way ANOVA -- Optimal Three-Treatment Response-Adaptive Designs for Phase III Clinical Trials with Binary Responses -- One-Half Fractions of a 23 Experiment for the Logistic Model -- Bayes Estimators of Covariance Parameters and the Influence of Designs -- Optimum Design for Correlated Fields via Covariance Kernel Expansions -- Generalized Probit Model in Design of Dose Finding Experiments -- Optimal Design of Bell Experiments -- A Comparison of Efficient Designs for Choices Between Two Options -- D-optimal Designs for Logistic Regression in Two Variables -- Design of Experiments for Extreme Value Distributions -- A Model Selection Algorithm for Mixture Experiments Including Process Variables -- D-optimal Designs for Nonlinear Models Possessing a Chebyshev Property -- A New Tool for Comparing Adaptive Designs; a Posteriori Efficiency -- Optimal Cutpoint Determination: The Case of One Point Design -- D-Optimal Designs for Regression Models with Length-Biased Poisson Response -- Efficient Sampling Windows for Parameter Estimation in Mixed Effects Models -- Quantile and Probability-level Criteria for Nonlinear Experimental Design -- Optimal Designs for the Exponential Model with Correlated Observations -- Determining the Size of Experiments for the One-way ANOVA Model I for Ordered Categorical Data -- Bayesian D s-Optimal Designs for Generalized Linear Models with Varying Dispersion Parameter -- Some Curiosities in Optimal Designs for Random Slopes -- The Within-B-Swap (BS) Design is A- and D-optimal for Estimating the Linear Contrast for the Treatment Effect in 3-Factorial cDNA Microarray Experiments -- D-optimal Designs and Equidistant Designs for Stationary Processes -- Optimal Designs for Discriminating among Several Non-Normal Models -- Optimal Orthogonal Three-Level Factorial Designs for Factor Screening and Response Surface Exploration…”

“…Limiting it to the articles that are; systematic review, controlled clinical trial and randomized controlled trial published on Spanish and English, between 1993 and 2015. …”

“…German criminal procedure does not provide for verbatim records of criminal trials. This is quite different from most other European countries where at least audio recordings exist. …”