“…Based on the body of experimental evidence indicating that TGF-β signaling has the potential to be a good therapeutic target in CRC, several anti-TGF-β drugs have been investigated in cancer clinical trials. Here, we presented a comprehensive collection of manuscripts regarding studies on targeting the TGF-β signaling in CRC to improve patient's prognosis and personalized treatments…”

“…It is up to this ragtag team to navigate trials, tribulations, site failures, and supply chain attacks, all on their path to save the company from disaster. …”

“…It is up to this ragtag team to navigate trials, tribulations, site failures, and supply chain attacks, all on their path to save the company from disaster. …”

“…Provides comprehensive coverage of essential topics including treatment of income and assets, deductions and credits, preliminary work and collection of taxpayer data, completion of the filing process, ethics and circular 230, and much more Helps you zero in on areas that need work, organize your study program, and concentrate your efforts Trial access to PasstheTaxExam.com included with this guide Over a million Americans make money preparing taxes every year, and you can become one of them by passing the RTRP exam. …”

“…Given this, the assessment of microstructure evolution in metallic systems is of extraordinary importance. Since the trial-error approach is a time-consuming and quite expensive methodology, the materials research community tends to employ a wide spectrum of computational approaches to simulate each chain of TMP and tune the processing variables to ensure the necessary microstructural state which will provide desired performance in the final product. …”

“…Treatment-related adverse events are unfortunately under-recognized by clinicians, scarcely spontaneously communicated by patients, and rarely investigated in clinical trials. The most frequent psychotropic compounds that could deteriorate sexuality and quality of life include antidepressants, antipsychotics and mood regulators. …”

“…Use the comprehensive knowledge from a team of DB2 developers and experts to get started with the latest DB2 trial version you can download at ibm.com/developerworks/downloads/im/db2/. …”

“…What You’ll Learn: Quickly master Python for data analysis without using a trial-and-error approach Understand the similarities and differences between Base SAS and Python Better determine which language to use, depending on your needs Obtain quick results…”

“…Readers listen to debates among Confucians, Daoists, and Buddhists and witness trials of faith and the performance of magical feats. …”

“…The EQ-5D-5L is one of the most widely used health related quality of life questionnaires around the world, with applications in clinical trials, population health surveys and routine outcomes measurement. …”

“…Many randomized clinical trials, epidemiological studies, and in vitro/in vivo mechanistic studies have since explored the role of eating nuts and its relation to health. …”

“…Treatment with psychoeducation was studied in four small trials with a total of 152 participants. The results show that: For women who both binge eat and have diabetes type 2, weekly group meetings over ten weeks with cognitive behavioral therapy may have a similar effect as weekly group meetings over ten weeks with another psychological therapy. …”

“…Methods We searched systematically for systematic reviews, randomised controlled trials and cohort studies in international databases. …”

“…We have included twelve randomised controlled trials with a total of more than 2000 participants where the studies reported sick leave as an outcome. …”

“…James's Park," and Daniel Defoe's Robinson Crusoe and Journal of the Plague Year--alongside other nonliterary primary sources and under-examined archival materials from the period, including treatises on animal trials, grain shortages, rabies, and comparative neuroanatomy. …”

“…The volume sheds new light on Navarre’s massive witch persecution (1608–14), illuminating the tragic cost of witch hunts and opening a new window onto our understanding of early modern Iberian life.Drawing from Spanish-language sources only recently discovered, Homza translates and annotates three court cases from Olague in 1611 and 1612. Two were defamation trials involving the slur “witch,” and the third was a petition for divorce filed by an accused witch and wife. …”

Acceso restringido usuarios UPSA

“…Despite the positive findings obtained in preclinical studies, results of clinical trials are not yet successful and clinical research is still ongoing. …”

“…Often a single study will not provide the answers and it is desirable to synthesise evidence from multiple sources, usually randomised controlled trials. This book takes an approach to evidence synthesis that is specifically intended for decision making when there are two or more treatment alternatives being evaluated, and assumes that the purpose of every synthesis is to answer the question “for this pre-identified population of patients, which treatment is ‘best’?” …”

“…Nine randomized controlled trials, with a total of 5863 participants, were included. …”