“…For monogenic diseases, target-based approaches may be well-suited to the identification of novel therapies. Most diseases, however, are caused by a combination of several genetic and environmental factors and are likely to require simultaneous modulation of multiple molecular targets/pathways for successful treatment. …”

“…It focuses on giving the reader mastery over the concepts, methods and metrics of digital video coding, so that readers have sufficient understanding to choose and tune coding parameters for optimum results that would suit their particular needs for quality, compression, speed and power. …”

“…Explore and implement deep learning to solve various real-world problems using modern R libraries such as TensorFlow, MXNet, H2O, and Deepnet Key Features Understand deep learning algorithms and architectures using R and determine which algorithm is best suited for a specific problem Improve models using parameter tuning, feature engineering, and ensembling Apply advanced neural network models such as deep autoencoders and generative adversarial networks (GANs) across different domains Book Description Deep learning enables efficient and accurate learning from a massive amount of data. …”

“…Who This Book Is For This book is best suited for project managers and Redmine administrators who have working knowledge of Redmine and who now want to get advanced practical knowledge to manage and monitor projects effectively and efficiently. …”

“…Most enterprise architecture initiatives employ one of the existing system architecture frameworks such as Zachman or The Open Group Architecture Framework, but these are not well-suited for enterprise architecture in a modern, agile organization. …”

“…About This Book The most up-to-date advanced practical guide on Drupal 8 with an in-depth look at all the advanced new features such as authoring, HTML markup, built-in web services, and more If you are looking to dive deep into Drupal 8 and create industry-standard web apps, then this is the ideal book for you All the code and examples are explained in great detail to help you in the development process Who This Book Is For This book is ideally suited to web developers, designers, and web administrators who want to dive deep into Drupal. …”

“…Toujours en progression - grâce notamment à une tarification qui reste attrayante - l'énergie photovoltaïque raccordée au réseau suit un plan de croissance contrôlé par l'Etat. D'ici 2020, le parc photovoltaïque français aura quintuplé. …”

“…You can automate tasks, reduce the learning curve, and improve productivity through a modern, simplified, and intuitive task-based, browser-based interface. z/OSMF is aimed at a mixed skills workforce: It is suited to both professionals who are new to z/OS and those who are already skilled in z/OS. …”

“…Python is a multi-paradigm programming language well suited to both object-oriented application development as well as functional design patterns. …”

“…Master PostgreSQL 12 features such as advanced indexing, high availability, monitoring, and much more to efficiently manage and maintain your database Key Features Grasp advanced PostgreSQL 12 concepts with real-world examples and sample datasets Explore query parallelism, data replication, database administration, and more Extend PostgreSQL functionalities to suit your organization's needs with minimal effort Book Description Thanks to its reliability, robustness, and high performance, PostgreSQL has become the most advanced open source database on the market. …”

“…See which network technologies are best suited to your priorities and processes and the tradeoffs between various alternatives. …”

“…Cette étude présente une analyse empirique d’un certain nombre des effets secondaires qui peuvent être associés à ces instruments, en considérant le cas des parcs naturels régionaux (PNR) français. L’analyse suit une démarche empirique quasi expérimentale (méthode des différences de différences) pour évaluer les effets des PNR sur le développement urbain à l’échelon de la municipalité. …”

“…The toolkit approach allows you to use this book to suit your unique needs: Are you new to the IT field? …”

“…Become a Professional Cloud Architect by exploring essential concepts, tools, and services in GCP and working through tests designed to help you get certified Key Features Plan and design a robust GCP cloud solution architecture Ensure the security and reliability of your cloud solutions and operations Test yourself by taking mock tests with up-to-date exam questions Book Description Google Cloud Platform (GCP) is one of the leading cloud service suites and offers solutions for storage, analytics, big data, machine learning, and application development. …”

“…You'll find the most current, real-world advice on customizing an LLC for your specific business needs, creating a great operating agreement, keeping accurate records, and new information on federal regulations and fees that are applicable to LLCs, as well as a link to online tools, forms, and documents Most of the previous drawbacks to forming an LLC have all but disappeared with the IRS having loosened restrictions and individual states following suit. Because LLCs are now more flexible, they remain an attractive option for those launching a new business or reorganizing an existing business. …”

“…Build customized solutions that fulfil your business requirements using the latest features of Jira 8 Key Features Learn how to customize Jira applications to suit your organizational requirements Extend Jira's capabilities for custom integrations with other products and services such as Slack and GitHub Explore practical recipes for troubleshooting and securing your Jira instances with best practices Book Description Jira is a project management tool used widely by organizations to plan, track, and release software. …”

“…With the help of this book, you will be able to speed up the process by designing effective ETL solutions using the Azure services available for handling and transforming any data to suit your requirements. With this cookbook, you'll become well versed in all the features of SQL Server Integration Services (SSIS) to perform data migration and ETL tasks that integrate with Azure. …”

“…From there, you will learn step by step, how to modify the default WordPress template CSS and file structure to suit your own design, one element at a time. You will learn about "The Loop", and how to use it on your homepage. …”

“…This unique approach to learning, combined with many small program examples and exercises at the end of each chapter, makes Programming in Objective-C ideally suited for either classroom use or self-study. This edition has been fully updated to incorporate new features in Objective-C programming introduced with Xcode 4.4 (OS X Mountain Lion) and Xcode 4.5 (iOS 6.) …”

“…The XIV Storage System is suited for mixed or random access workloads, including online transaction processing, video streamings, images, email, and emerging workload areas, such as Web 2.0 and storage cloud. …”