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  1. 1281
    por Ruiz Vadillo, Diana María
    Publicado 2019
    Tabla de Contenidos: “…DISPOSITIVOS DE PROTECCIÓN DE LÍNEAS Y RECEPTORES (...) -- 3.1. PROTECCIÓN CONTRA SOBREINTENSIDADES -- 3.2. …”
    Libro electrónico
  2. 1282
    Publicado 2017
    Tabla de Contenidos: “…6.2.4.1 - Cyclic Voltammetry -- 6.2.4.2 - Differential Pulse Voltammetry -- 6.2.4.3 - Square Wave Voltammetry -- 6.2.5 - Electrochemical Impedance Spectroscopy -- 6.2.6 - Electronic Tongue: Concepts, Principles, and Applications -- List of Symbols -- References -- 7 - Molecular Modeling Applied to Nanobiosystems -- 7.1 - Introduction -- 7.1.1 - Molecular Modeling -- 7.1.2 - Computer-Assisted Molecular Modeling -- 7.2 - Basic Representation Types -- 7.3 - Biomolecules and Protein Modeling -- 7.3.1 - Biomolecules -- 7.3.2 - Proteins -- 7.3.3 - Protein Structure -- 7.3.4 - Types of Protein and Biomolecule Representations -- 7.3.5 - Biological Structure Databases -- 7.3.6 - Protein Structure Visualization, Manipulation, and Analysis Tools -- 7.4 - Molecular Computer Modeling Methods Applied To Biomolecules -- 7.4.1 - Classical Methods -- 7.4.1.1 - Molecular Dynamics -- 7.4.1.1.1 - Molecular dynamics and related potentials -- 7.4.1.1.2 - Molecular dynamics simulation methods -- 7.4.1.2 - Molecular Docking -- 7.4.1.2.1 - Receptor-ligand molecular docking -- 7.4.1.2.2 - Genetic algorithms -- 7.4.2 - Hybrid Methods (Quantum Mechanics/Molecular Mechanics) -- 7.4.2.1 - Introduction to Hybrid Methods -- 7.4.2.2 - Simulation of Biomolecular Systems -- 7.4.2.3 - Programs for Using the QM/MM Methodology -- 7.4.2.4 - Theoretical Foundations and Mathematical Description -- 7.4.2.5 - Electrostatic Interactions -- 7.4.2.6 - Applications of QM/MM in Molecular Systems -- 7.4.3 - Structural Characterization -- 7.4.3.1 - X-Ray Diffraction -- 7.4.3.2 - Nuclear Magnetic Resonance -- 7.4.3.3 - Protein Modeling by Homology -- 7.5 - Some Recent Applications -- 7.5.1 - Applications in the Pharmaceutical Industry -- 7.5.1.1 - Pharmaceutical Development -- 7.5.1.2 - Rational Pharmaceutical Design -- 7.5.2 - Technological Applications…”
    Libro electrónico
  3. 1283
    Tabla de Contenidos: “…Drinking Water and Health -- Copyright -- Contents -- Preface -- Historical Note -- Importance of Water Filtration -- Chlorination, The Most Significant Advance in Water Treatment -- Summary -- REFERENCES -- I Approach to the Study -- INTRODUCTION -- WATER CONSUMPTION -- RISK AND SAFETY -- MICROBIOLOGICAL CONTAMINANTS -- PARTICULATE CONTAMINANTS -- INORGANIC SOLUTES -- ORGANIC SOLUTES -- RADIOACTIVE CONTAMINANTS -- SUSCEPTIBLE SUBGROUPS AND OTHER CONSIDERATIONS -- REFERENCES -- II Chemical Contaminants: Safety And Risk Assessment -- EFFECTS ON HEALTH -- Reversibility of Chemical Injury -- Perspectives and Perceptions of Effects -- Irreversible (Self-Propagating) Effects -- Nonreversible Effects -- Reversible Effects -- IRREVERSIBLE TOXICITY -- Summary of Principles for Extrapolating Animal Toxicity To Humans -- The General Problem of Extrapolation -- Specific Problems in Extrapolation -- Size of Animals -- Number of Animals -- Environmental Differences -- Absorption -- Distribution and Storage -- Metabolic Differences -- Excretion and Reabsorption -- Differences in Receptor Sites -- Design of Laboratory Experiments on Animals -- Current Capability to Extrapolate -- THRESHOLDS -- Biological Considerations -- Consideration of the Dose-Response Relationship -- Examination of Experimental Dose-Response Curves -- Heterogeneity of the Population -- Statistical Considerations -- HIGH-DOSE TO LOW-DOSE EXTRAPOLATION -- Dose-Response Models -- Appropriateness of Data for Low-Dose Extrapolation -- INTERACTIONS -- SUMMARY-CHEMICAL CONTAMINANTS: SAFETY AND RISK ASSESSMENT -- Principle 1 -- Effects in Animals, Properly Qualified, are Applicable to Man -- Principle 2 -- Methods do not Now Exist to Establish a Threshold for Long-Term Effects of Toxic Agents -- Principle 3.…”
    Libro electrónico
  4. 1284
    por Institute of Medicine (U.S.).
    Publicado 1994
    Tabla de Contenidos: “…Military and the Herbicide Program in Vietnam -- MILITARY AND DEMOGRAPHIC CHARACTERISTICS OF VIETNAM VETERANS -- Estimates of the Number of Military Personnel Serving in Vietnam -- Federal Estimates -- Other Survey Estimates -- Military and Demographic Characteristics -- Studies of Women Veterans -- THE MILITARY USE OF HERBICIDES IN VIETNAM -- Operation Ranch Hand -- Herbicide Formulations -- Military Herbicides -- Level of Toxic Contaminants -- Termination of the Program -- Disposal of Surplus Herbicides -- Ground Spraying of Herbicides -- The HERBS and Services HERBS Tapes -- Geographical Distribution of Herbicide Sprays -- SUMMARY -- REFERENCES -- 4 Toxicology -- OVERVIEW -- Chemistry -- Exposure and Metabolism -- Carcinogenicity: TCDD -- Mechanism of Action -- Carcinogenicity: Herbicides -- Mechanism of Action -- Immunotoxicity: TCDD -- Mechanism of Action -- Immunotoxicity: Herbicides -- Reproductive and Developmental Toxicity: TCDD -- Mechanism of Action -- Reproductive and Developmental Toxicity: Herbicides -- Other Toxicity: TCDD -- Other Toxicity: Herbicides -- TOXICITY PROFILE OF TETRACHLORODIBENZO-P-DIOXIN -- Introduction -- Exposure and Pharmacokinetics -- Bioavailability Following Various Routes of Exposure -- Distribution -- Metabolism -- Excretion -- Mechanism of Action -- Introduction -- Ah Receptor -- Non-Ah-Mediated Toxicity -- Health Outcomes in Animal Studies -- Carcinogenicity -- Immunotoxicity -- Hepatotoxicity -- Reproductive and Developmental Toxicity -- Reproductive Toxicity -- Neurotoxicity -- Metabolic Toxicity…”
    Libro electrónico
  5. 1285
    Publicado 2017
    Tabla de Contenidos: “…8.7.2 Separation of Source and Target (Receptor)…”
    Libro electrónico
  6. 1286
    Tabla de Contenidos: “…Cardiología -- Medicamentos antianginosos -- Medicamentos antiarrítmicos -- Glucósidos cardíacos -- Inhibidor dual del receptor de angiotensina y neprilisina (ARNI) -- Anticoagulación en fibrilación auricular -- Medicamentos antihipertensivos -- Antihipertensivos combinados -- Terapia antihipertensiva inicial -- Emergencia y crisis hipertensivas -- Catecolaminas y otros inotrópicos -- Medicamentos útiles en reanimación cardiocerebro pulmona -- Lecturas recomendadas -- Capítulo 9. …”
    Libro electrónico
  7. 1287
    por Institute of Medicine Staff
    Publicado 1999
    Tabla de Contenidos: “…DISCUSSION -- IV ASSESSMENT -- 9 Methodological Issues in Assessment of Human Immune Function -- INTRODUCTION -- RATIONALE FOR IMMUNE ASSESSMENT -- THE IMMUNE SYSTEM -- SELECTION AND DEVELOPMENT OF THE TEST SYSTEM -- In Vivo Assessment of Immune Response -- In Vitro Assessment of Immune Response -- Proliferative Response -- Development of Effector Cell Response -- Assessment of Cell Types by Flow Cytometry -- AUTHOR'S CONCLUSIONS -- References -- DISCUSSION -- 10 Application of Whole-Blood Cultures to Field Study Measurements of Cellular Immune Function In Vitro -- BACKGROUND -- METHODS AND RESULTS -- Blood Donors -- Blood Collection -- Lymphocyte Proliferation in Whole-Blood Cultures -- Amount of Blood per Culture -- Duration of Incubation of Whole-Blood Cultures -- Duration of 3H-Thymidine Label of Whole-Blood Cultures -- Finalized Durations of Cell Culture and 3H-Thymidine Labeling -- Data Presentation of Lymphocyte Proliferation in Whole-Blood Cultures -- Effects of Holding and Shipping Blood on Whole-Blood Lymphocyte Proliferation -- Cytokine Production and Receptor Release In Vitro -- Concentration of Stimulant per Culture -- AUTHOR'S CONCLUSION -- References -- DISCUSSION -- V NUTRITION -- 11 Glutamine -- INTRODUCTION -- PHYSIOLOGIC BIOCHEMISTRY -- GLUTAMINE AND IMMUNE FUNCTION -- GLUTAMINE AND THE GASTROINTESTINAL TRACT -- AUTHOR'S DISCUSSION AND CONCLUSIONS -- References -- DISCUSSION -- 12 Vitamin A and Immune Function -- INTRODUCTION -- CLINICAL MANIFESTATIONS OF VITAMIN A DEFICIENCY -- EPIDEMIOLOGY OF VITAMIN A DEFICIENCY -- VITAMIN A DEFICIENCY IN ADULTS -- VITAMIN A DEFICIENCY AS AN IMMUNODEFICIENCY DISORDER -- CONSIDERATIONS FOR ADULT MEN AND WOMEN -- AUTHOR'S CONCLUSIONS -- References -- DISCUSSION -- 13 Vitamin E, Vitamin C, and Immune Response: Recent Advances -- INTRODUCTION -- AGING -- Vitamin E -- Vitamin C -- CANCER -- AIDS…”
    Libro electrónico
  8. 1288
    Publicado 2023
    “…It is currently apparent that extracellular ATP's physiological effect is mediated by its interaction with specific purinergic receptors. All purinergic receptors are divided into P1-purinoreceptors and P2-purinoreceptors. …”
    Libro electrónico
  9. 1289
    Publicado 2016
    “…G protein-coupled receptors (GPCRs) represent a large and physiologically important class of cell surface receptors. …”
    Libro electrónico
  10. 1290
    Publicado 2020
    “…Engagement of PRRs by microbial or host-derived danger signals coordinates the cellular innate immune response. While some receptors such as Toll-like Receptors (TLRs) and C-type Lectin Receptors (CLRs) are membrane bound, others like the Retinoic-acid-Inducible Gene I (RIG-I)-Like Receptors (RLRs), Nucleotide-binding Oligomerization Domain (NOD)-Like Receptors (NLRs) and several DNA receptors (e.g. …”
    Libro electrónico
  11. 1291
    por Sánchez-Bayón, Antonio
    Publicado 2019
    Tabla de Contenidos: “…OBSTÁCULOS EN EL EMISOR -- 8.5.2. OBSTÁCULOS DEL RECEPTOR -- 8.5.3. EXCESO DE INFORMACIÓN -- 8.5.4. …”
    Libro electrónico
  12. 1292
    Publicado 1985
    Tabla de Contenidos: “…-- Electrophoretic characterization of lymphocyte separated on Percoll density gradients / Enrichment of chicken peripheral blood B lymphocytes by preparative free flow electrophoresis / A method of analysing a polymodal histogram of electrophoretic mobility / Malignant transformation - cell characterization in leukemia -- Differences in the electrophoretic mobilities of pigmented and non-pigmented melanoma cells / Electrophoresis of mouse leukocytes and leukemia cells / Application of the cell electrophoresis for characterisation of leukemic cells / Electrophoretic mobility distribution of cells in leukemia / Electrophoretic mobility distributions and membrane phenotypes of some hemopoietic cell lines and fresh leukemic cells / Electrophoresis of leukemic white blood cells with Lazypher / Cell electrophoretic and size distribution investigations of thrombocytes of patients with acute leukemia and hemorrhagic diathesis / Influence of exogenic factors: radiation, stress, antibodies, drugs, mitogens -- Cell electrophoretic mobility as an aid to study biological systems / The biochemical and morphologic blood analysis and electrophoretic behaviour of rat erythrocytes after gamma irradiation / Electrophoretic mobility of erythrocytes from gamma - or alpha-irradiated rats protected by adeturone / The use of the electrophoretic microscope PARMOQUANT 2 for the investigation of erythrocytes in dynamics in the therapy of patients with psoriasis / Effect of ultraviolet irradiation on electrophoretic behaviour of red blood cells / Stress induced alterations in electrophoretic and morphological properties of thymus cells / Erythrocyte electrophoretic mobility and its membrane state in conditions of adrenalin stress / Some aspects of cell electrophoresis application in immunological investigations / Application of antibodies to cell electrophoresis / In vitro differential effects of chlorpromazine on the surface charge of murine T cell subsets / Purification of intestinal intraepithelial lymphocytes by preparative electrophoresis / Microelectrophoresis of epithelial cells and lymphocytes / Monitoring of ATG production using cell electrophoresis / Cell electrophoretic detection of pregnancy factors / Isolation of cationic proteins from bovine allantoic fluid - A preliminary study of their biological properties / Preliminary investigation of the effect of chinese herbs on lymphocyte stimulation by cell electrophoresis / The variation in the electrophoretic mobility of erythrocytes after massive blood replacement by "Perftoran" / The application of cell electrophoresis to the production of erythrocyte diagnostic preparations / Electrophoretic mobility, ecto-ATPase activity and mitotic rate of thymocytes after treatment of mice with immunosuppressive drugs / On the sensitivity of several indicators of cytotoxic drug effects of thymocytes in vitro / Discrimination between functional and non-functional ConA-receptors by means of cell electrophoresis / Mechanism of cell charge alteration of T lymphocytes after ConA stimulation / The effect of peanut agglutinin on the electrophoretic mobility of lymphocyte populations / Phytohaemagglutinin-induced changes of electrophoretic mobility and functional activity of PEA chloroplasts / Cell electrophoretic detection of the influence of transfer factor on trypsinated T lymphocytes / Detection of multiple sclerosis -- Family studies in multiple sclerosis: Frequency amongst relatives of a proband / Multiple sclerosis: Diagnosis by He-Ne laser irradiation of erythrocytes / Laser Cytopherometry in multiple sclerosis / Detection of lymphokines: methodical aspects, cancer, renal transplantation, drugs -- The macrophage electrophoretic mobility test : Clinical applications: A guide / Enrichment and characterization of the macrophage slowing factor released by mononuclear blood cells upon contact with CEA or teratoma - derived proteins / Characterization of the phytohaemagglutinin-induced macrophage slowing factor (PHA-MSF) / Failure of the MEM test for cancer diagnosis / Long-time study in melanoma patients with TAA-melanoma and PPD 8 years after primary operation by MEM-test / Investigation of obliterative vascular diseases with the PARMOQUANT 2 / The transfer of cellular immunity in the in vitro MEM test by immune RNA isolated from guinea-pigs immunized with basic protein of human glioma / Alteration of electrophoretic mobility of guinea pig peritoneal macrophages by carrageenan / The tanned erythrocyte electrophoretic mobility (TEEM) test…”
    Libro electrónico
  13. 1293
    Publicado 2022
    Tabla de Contenidos: “…Abnormal Tyrosine Kinase Activity and Signaling in Cancer -- Tyrosine Kinase Inhibitors -- Tyrosine Kinase Receptors and Cardiomyopathy -- VEGF/VEGFR Signaling -- PDGF/ PDGFR Signaling -- c-KIT Signaling -- TKI-Induced Cardiovascular Dysfunction -- Hypertension -- Arrhythmias -- TKIs and Ion Homeostasis -- TKI-Mediated Potassium Ion Channel Dysfunction -- TKI Dysregulation of Calcium-Mediated Signaling -- TKIs and Sodium Channels: An Unexplored Territory -- TKIs and Heart Failure -- TKIs and Thromboembolism -- Monitoring and Treatment of TKI-Induced Cardiotoxicity -- Part III: Immune Checkpoint Inhibitors -- T-Cell Activation and Regulation -- Mechanisms of ICI-Mediated Cardiac Disorders -- Arrhythmias -- Myocarditis and Pericarditis -- Heart Failure -- Monitoring and Treatment of ICI-Associated Cardiotoxicity -- Part IV: CAR T-Cell Immunotherapy -- CAR T-Cell Mechanism of Action -- Proposed Mechanisms of Cardiotoxicity in CAR T-Cell Therapy -- JAK/STAT Signaling Pathway -- IL-6 -- TNFα -- Interleukin 1 -- Off-Target Affects -- Monitoring of CAR T-Cell Associated Cardiotoxicity -- Current and Proposed Treatments for CAR T-Cell-Induced Cardiotoxicity -- References -- Protein Phosphatase Signaling in Cardiac Myocytes -- Introduction -- The Kinase-Phosphatase Axis -- Protein Phosphatase Families and Genetics -- Localization and Binding Partners of Protein Phosphatases -- Mouse Models -- Protein Phosphatases in Cardiovascular Disease -- PP1 in Cardiovascular Disease -- PP2A in Cardiovascular Disease -- PP2B in Cardiovascular Disease -- Conclusions and Future Directions -- References -- Metabolic Regulation of Mitochondrial Dynamics and Cardiac Function -- Mitochondrial Dynamics: Fusion and Fission Events -- Diabetes-Related Cardiac Ischemia and Reperfusion Injury -- Diabetes-Related Cardiac Chronic Remodeling, Hypertrophy, and Failure…”
    Libro electrónico
  14. 1294
    Publicado 2006
    Tabla de Contenidos: “…Clasificación de secuencias. Receptores de correlación -- 9.13. Correlación de secuencias de longitud finita…”
    Libro electrónico
  15. 1295
    Publicado 2021
    Tabla de Contenidos: “…ANALÍTICA DE LA TEMPERATURA EFECTIVA DE RUIDO DE UN RECEPTOR DESDE (...) -- 5.18. LA FIGURA DE RUIDO DE LOS ELEMENTOS PASIVOS -- GUÍA DE ACTIVIDADES No 5 -- 6 MODULACIÓN POR PULSOS -- OBJETIVOS -- CONTENIDOS -- 6.1. …”
    Libro electrónico
  16. 1296
    Publicado 2010
    Tabla de Contenidos: “…Aspectos clínicos de los receptores de estrógenos y de progesterona -- Capítulo 30. …”
    Libro electrónico
  17. 1297
    Publicado 2020
    Tabla de Contenidos: “…Los documentos jurídicos relevantes receptores del derecho al desarrollo…”
    Libro electrónico
  18. 1298
    Publicado 2019
    Tabla de Contenidos: “…Cell Adhesion Molecules and Membrane Receptors Allow the Cell to Interact with its Environment -- Focus Figure 3.3: G Proteins -- Part 2: The Cytoplasm -- 3.7. …”
    Libro electrónico
  19. 1299
    por Bosch, Thomas C. G.
    Publicado 2020
    Tabla de Contenidos: “…References -- Chapter 4: Decoding cellular dialogues between sponges, bacteria, and phages -- 4.1 Introduction -- 4.2 Host-bacteria dialogue -- 4.2.1 Sponge immune receptors -- 4.2.2 Microbe associated molecular patterns (MAMPs) -- 4.3 Bacteria-bacteria dialogue -- 4.3.1 Quorum sensing -- 4.3.2 Quorum quenching -- 4.4 Phage-bacteria-host dialogue -- 4.4.1 Phage diversity and host-specificity -- 4.4.2 Ankyphages aid symbionts in immune evasion -- 4.5 Conclusions and future perspectives -- Acknowledgments -- References -- Chapter 5: Symbiotic interactions in the holobiont Hydra -- 5.1 Introduction -- 5.2 Interactions between Hydra viridissima and the Chlorella photobiont -- 5.2.1 Location and transmission of the photobiont -- 5.2.2 Mutual benefits -- 5.2.3 Establishment and maintenance of the Chlorella-Hydra symbiosis -- 5.2.4 Molecular mechanisms involved in maintaining the symbiosis -- 5.3 Interactions between Hydra and symbiotic bacteria -- 5.3.1 Spatial localization of the bacteria in the Hydra host -- 5.3.2 Bacteria provide protection against fungal infection -- 5.3.3 The innate immune system shapes the host microbiome -- 5.3.4 Crosstalk between innate immunity and stem cell factors -- 5.3.5 Crosstalk between the microbiota and the nervous system -- 5.3.6 Effect of bacteria on host physiology -- 5.4 Conclusion: Hydra, an excellent model to understand inter-species interactions -- Acknowledgments -- References -- Chapter 6: Hydra and Curvibacter: An intimate crosstalk at the epithelial interface -- 6.1 Introduction -- 6.2 Hydra and Curvibacter: The ideal duo to understand inter-kingdom communications -- 6.3 Spatial localization and transmission of Curvibacter -- 6.4 Establishment and carrying capacity of Curvibacter colonization -- 6.5 Curvibacter function in the Hydra metaorganism -- 6.6 Inter-kingdom communication between Hydra and Curvibacter…”
    Libro electrónico
  20. 1300
    Publicado 2019
    Tabla de Contenidos: “…Taking a Closer Look -- Concept Boost: Connecting a DNA Triplet to a Particular Amino Acid -- The Big Picture of Protein Synthesis -- A&amp -- P in the Real World: Drugs and Membrane Receptors -- A&amp -- P in the Real World: Dehydration, Sports Drinks, and Water -- A&amp -- P in the Real World: Cystic Fibrosis -- A&amp -- P in the Real World: Lysosomal Storage Diseases -- A&amp -- P in the Real World: Primary Ciliary Dyskinesia -- A&amp -- P in the Real World: Toxicity of the "Death Cap" Mushroom -- A&amp -- P in the Real World: Spindle Poisons -- 4. …”
    Libro electrónico