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  1. 4461
    Tabla de Contenidos: “…Machine generated contents note: Introduction PART I: BACKGROUND 2 Vertebrate Immunity 2.1 Nonspecific Immunity 2.2 Specific Immunity: Antigens and Epitopes 2.3 B Cells and Antibodies 2.4 T Cells and MHC 2.5 Summary 3 Benefits of Antigenic Variation 3.1 Extend Length of Infection 3.2 Infect Hosts with Prior Exposure 3.3 Infect Hosts with Genetically Variable Resistance 3.4 Vary Attachment Characters 3.5 Antigenic Interference 3.6 Problems for Future Research PART II: MOLECULAR PROCESSES 4 Specificity and Cross-Reactivity 4.1 Antigens and Antibody Epitopes 4.2 Antibody Paratopes 4.3 Antibody Affinity Maturation 4.4 Natural Antibodies-Low-Affinity Binding to Diverse Antigens 4.5 Affinity versus Specificity 4.6 Cross-Reaction of Polyclonal Antibodies to Divergent Antigens 4.7 T Cell Epitopes 4.8 Every Host Differs 4.9 Problems for Future Research 5 Generative Mechanisms 5.1 Mutation and Hypermutation 5.2 Stochastic Switching between Archival Copies 5.3 New Variants by Intragenomic Recombination 5.4 Mixing between Genomes 5.5 Problems for Future Research PART III: INDIVIDUAL INTERACTIONS 6 Immunodominance within Hosts 6.1 Antibody Immunodominance 6.2 CTL Immunodominance 6.3 Sequence of Exposure to Antigens: Original Antigenic Sin 6.4 Problems for Future Research 7 Parasite Escape within Hosts 7.1 Natural Selection of Antigenic Variants 7.2 Pathogen Manipulation of Host Immune Dynamics 7.3 Sequence of Variants in Active Switching from Archives 7.4 Ecological Coexistence of Variants within a Host 7.5 Problems for Future Research PART IV: POPULATION CONSEQUENCES 8 Genetic Variability of Hosts 8.1 Polymorphisms in Specificity 8.2 Polymorphisms in Immune Regulation 8.3 Problems for Future Research 9 Immunological Variability of Hosts 9.1 Immunological Memory 9.2 Kinds of Parasites 9.3 Immunodominance of Memory 9.4 Cross-Reactivity and Interference 9.5 Distribution of Immune Profiles among Hosts 9.6 Problems for Future Research 10 Genetic Structure of Parasite Populations 10.1 Kinds of Genetic Structure 10.2 Pattern and Process 10.3 Genome-wide Linkage Disequilibrium 10.4 Antigenic Linkage Disequilibrium 10.5 Population Structure: Hosts as Islands 10.6 Problems for Future Research PART V: STUDYING EVOLUTION 11 Classifications by Antigenicity and Phylogeny 11.1 Immunological Measures of Antigenicity 11.2 Phylogeny 11.3 Hypothetical Relations between Immunology and Phylogeny 11.4 Immunology Matches Phylogeny over Long Genetic Distances 11.5 Immunology-Phylogeny Mismatch with Radiations into New Hosts 11.6 Short-Term Phylogenetic Diversification Driven by Immunological Selection 11.7 Discordant Patterns of Phylogeny and Antigenicity Created by Within-Host Immune Pressure 11.8 Problems for Future Research 12 Experimental Evolution: Foot-and-Mouth Disease Virus 12.1 Overview of Antigenicity and Structure 12.2 Antibody Escape Mutants 12.3 Cell Binding and Tropism 12.4 Fitness Consequences of Substitutions 12.5 Problems for Future Research 13 Experimental Evolution: Influenza 13.1 Overview of Antigenicity and Structure 13.2 Antibody Escape Mutants 13.3 Cell Binding and Tropism 13.4 Fitness Consequences of Substitutions 13.5 Experimental Evolution of Other Pathogens 13.6 Problems for Future Research 14 Experimental Evolution: CTL Escape 14.1 Cleavage and Transport of Peptides 14.2 MHC Binding. 14.3 TCR Binding 14.4 Functional Consequences of Escape 14.5 Kinetics of Escape 14.6 Problems for Future Research 15 Measuring Selection with Population Samples 15.1 Kinds of Natural Selection 15.2 Positive Selection to Avoid Host Recognition 15.3 Phylogenetic Analysis of Nucleotide Substitutions 15.4 Predicting Evolution 15.5 Problems for Future Research 16 Recap of Some Interesting Problems 16.1 Population-Level Explanation for Low Molecular Variability 16.2 Molecular-Level Explanation for Population Dynamics 16.3 Binding Kinetics and the Dynamics of Immunodominance 16.4 Diversity and Regulation of Archival Repertoires 16.5 Final Note…”
    Libro electrónico
  2. 4462
    por Hamborg, Felix
    Publicado 2023
    “…The approach named person-oriented framing analysis identifies the coverage’s different perspectives on the event by assessing how articles portray the persons involved in the event. In contrast to prior automated approaches, the identified frames are more meaningful and substantially present in person-oriented news coverage. …”
    Libro electrónico
  3. 4463
    Publicado 2020
    “…He concludes with an examination of alternative ways to farm in New Zealand, showing how the prior histories of colonisation and modernisation reveal important ways to farm differently in post-colonial worlds. …”
    Electrónico
  4. 4464
    Publicado 2005
    “…The NFSv4 implementation in AIX 5L has now expanded to provide core features that make it capable of providing a much broader range of distributed file system services than any prior version of NFS. The scope of this book includes methods for implementing NFSv4 in the enterprise and extensive coverage of methods for how it can potentially be used as a migration target for existing AFS-based and DCE/DFS-based enterprise file systems…”
    Libro electrónico
  5. 4465
    Publicado 2022
    “…The book does not require prior knowledge about crisis communication and crisis management; it contains summaries of crisis communication and management before exploring the more specialized topic of extreme crises. …”
    Libro electrónico
  6. 4466
    por Rius, Antoni, 1663-1716
    Publicado 1692
    “…Presentado Fr. Domingo Torrabadell Prior del Convento de Santo Domingo" -- Catàleg manual de la col·lecció Bonsoms…”
    Accés Lliure
    Accés lliure
    Libro
  7. 4467
    Sefer ben Zequnim nehlaq le-shene halaqim ..
    ספר ‏בן זקונים : ‏נ‏חלק לשני חלקים ...
    Publicado 1793
    Libro
  8. 4468
    Publicado 2023
    “…Challenging many established narratives of literary history, this book investigates how the earliest known Greek poets (seventh to fifth centuries BCE) signposted their debts to their predecessors and prior traditions - placing markers in their works for audiences to recognise (much like the 'Easter eggs' of modern cinema). …”
    Libro electrónico
  9. 4469
    Publicado 2023
    “…This welcome volume uncovers an overemphasis in prior scholarship on the relevance of "crusading" agendas in medieval romance, and highlights the shared investments of Christians and Muslims in Iberia's political, creedal, cultural, and mercantile networks in the Mediterranean world…”
    Libro electrónico
  10. 4470
    Publicado 1956
    Tabla de Contenidos: “…Praefatio qua, in indice sub titulo: Index Indicum, evolvitur omnium tabularum series. Indicum Pars Prior.---Indices Generales. Series Prima.---Indices Generales Auctorum. col. 4 Table française ndicative des auteurs, des ouvrages et des éditions. 10 Index auctorum alphabeticus. 134 Index auctorum chronologicus. 174 Index auctorum statisticus. 226 Index alius auctorum statisticus, in quo quisque scriptor ad suam revocatur dioecesim. 238Index auctorum hierarchicus. 266 Index auctorum cleri regularis. 283 Index auctorum cleri saecularis. 290 Index auctorum laicorum, tam virorum quam mulierum. 302 Index scriptorum recentiorum, editorum, adnotatorum, etc. 307 Index omnium auctorum biographicus. 399 Index auctorum analyticus. 547 Series Secunda.…”
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    Libro
  11. 4471
    por Staiger, Roger
    Publicado 2018
    “…Designed to provide the scalable basis of pro forma modelling for real estate projects...introduces...the basics of real estate finance theory prior to providing a step-by-step guide for financial real estate model construction using Excel...an innovative new financial metric, P(Gain), which quantifies the probability of a return of capital and answers the most basic question for investing, "What is the probability I get my money back?"...…”
    Libro
  12. 4472
    Publicado 2019
    “…The authors included here pursue three major questions: Is the state of American political discourse today really that bad, compared to prior eras; what lessons about civility can we draw from the 2016 election; and how have changes in technology such as the development of online news and other means of mediated communication changed the nature of our discourse? …”
    Libro
  13. 4473
  14. 4474
  15. 4475
    Publicado 2024
    “…The contributors pursue lines of argument that complement, enhance, or challenge Allan's prior investigations into these root metaphors of early Chinese philosophy, whether by explicitly engaging with conceptual metaphor theory or, more indirectly, by addressing meaning construction in a broader sense. …”
    Libro
  16. 4476
    Publicado 2023
    “…Given that the Council had only opened less than a year prior, on 8 December 1869, the act was emblematic. …”
    Libro
  17. 4477
  18. 4478
    por Berceo, Gonzalo de, 1196-1252
    Publicado 2003
    Tabla de Contenidos: “…Milagros de Nuestra Sennora; Página legal; Índice; Prólogo; Milagro I La casulla de san Ildefonso; Milagro II El sacristán fornicario; Milagro III El clérigo y la flor ; Milagro IV El galardón de la virgen; Milagro V El pobre caritativo; Milagro VI El ladrón devoto; Milagro VII San Pedro y el monje mal ordenado; Milagro VIII El romero engañado por el enemigo malo; Milagro IX El clérigo simple; Milagro X Los dos hermanos; Milagro XI El labrador avaro; Milagro XII El prior de san Salvador y el sacristán Uberto ; Milagro XIII El nuevo obispo de Pavía…”
    Libro electrónico
  19. 4479
    Publicado 2003
    Tabla de Contenidos: “…Front matter -- ÍNDICE -- Los consulados hispanoamericanos como tema / La institución consular y el derecho comercial: conceptos, evolución y pervivencias / Gestión del derecho de alcabalas y conflictos por la representación corporativa: la transformación de la norm atividad electoral del Consulado de México en el siglo XVII / Las elecciones de prior, cónsules y diputados en el Consulado de México en la primera mitad del siglo XVIII: la formación de los partidos de montañeses y vizcaínos / El parecer de la élite de comerciantes del Consulado de la ciudad de México ante la operación del libre comercio (1791-1793) / Sobre los orígenes comerciales del Consulado de Veracruz: comercio libre y mercado interno a fines del siglo XVIII(1778-1795) / Mercado, élite e institución: el Consulado de comercio de G uadalajara y el control corporativo de las importaciones en el mercado interno novohispano / Los doce primeros años de la Junta Económica y de G obierno del Real Consulado de La Habana / El Consulado de Lima y la política comercial española frente a las coyunturas de cambio de fines del periodo colonial (1806-1821) / Abreviaturas -- Bibliografía -- Autoras y autores…”
    Libro electrónico
  20. 4480
    Publicado 1995
    Tabla de Contenidos: “…The Empires And States Of The Hellenistic World Prior To The Roman Conquest ""; ""5. Political Ideology And Ruler Cult ""; ""Â 2 Society And Economics ""; ""1. …”
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    Libro electrónico