“…However, along with the discovery of additional genes associated with human cardiac diseases, the analysis of large dataset of genetic information uncovered a much more complex and variegated landscape, which often departs from the comfort zone of the monogenic Mendelian diseases image that clinical molecular geneticists have been well acquainted with for many decades. It is now clear that, in addition to highly penetrant genetic variants, which in isolation are able to recapitulate the full clinical presentation when expressed in animal models, we are now aware that a small but significant fraction of subjects presenting with cardiac muscle diseases such as cardiomyopathies or primary arrhythmias such as long QT syndrome (LQTS), may harbor at least two deleterious variants in the same gene (compound heterozygous) or in different gene (double heterozygous). …”

“…At the time of compiling this e-book many aspects of ion transport under salinity stress are not yet well understood. …”

“…This dual activation makes them perfect sensors for many cellular events that require integration between intracellular calcium levels and electrical signals. …”

“…Although natural and managed grasslands represent pivotal ecosystems, many aspects of how they function are poorly understood. …”

“…Through sheer complexity, however, many important biological problems are at present intractable, and it is not clear whether we will ever be able to solve such problems. …”

“…It has become more evident that many microalgae respond very differently than land plants to diverse stimuli. …”

“…Through the development of a language, books on art whose publications are growing in the north of the Alps from 1600, aim at the construction of a common knowledge for the use of painters and amateurs. Their many translations, published since the modern era, also testify to their role of diffusion agent in constant adaptation to the readership to which they are addressed. …”

“…On one hand, portions of the viruses are infectious for animals including humans, and cause various diseases in infected hosts by distinct mechanisms and at a different level of severity. While many of viruses are known to co-exist quietly with their hosts, pathogenic viruses certainly affect and threaten our society as well as individuals to provoke serious medical or economic attention. …”

“…Invasive fungal diseases have increased many fold over the past 50 years. Current treatment regimens typically require prolonged administration of antifungal medications that can have significant toxicity. …”

“…Regulation of bacterial gene expression, replication and segregation control mechanisms, cell to cell communication via quorum sensors, and the relatively recent finding of bacterial immunity via CRISPR, have led to the development of many, and very important new tools in biotechnology and the emerging field of molecular medicine. …”

“…However, subversion-a critical part of the repertoire of many insurgent groups-remains a neglected subject. …”

“…Although such judgments often rest on subtle intuitions, there is no systematic methodology for eliciting them, and their apparent instability and unreliability have led many to conclude that they should be abandoned as a source of data…”

“…Natural pine forests characterize many landscapes preserved over time, either as a result of a specific forest management practice or a disturbance. …”

“…Due to their diverse and dynamic activities, they have been used for the production of many interesting products, such as beer, wine, bread, biofuels, and biopharmaceuticals. …”

“…In recent years, a considerable effort has been devoted to investigating the role of many virulence traits in the pathogenic outcome of fungal infections. …”

“…Although the using renewable energy technologies and the incorporation of plug-in DGs into SDS may have positive effects on congestion management, power loss reduction, and sustainability, they may create some difficulties relating to manage the system optimally by considering the intermittency of renewable resources in power production and uncertainties. Many researches have been carried out to deliver the high-quality power to the end-users with acceptable reliability. …”

“…It is not surprising, then, that when approached from an academic perspective, it reveals enormous potential for interdisciplinary research, which has proven extremely attractive to many scholars from different continents, disciplines, and schools of academic inquiry. …”

“…Rare earth elements have significant physical and chemical properties, which have been made indispensable in many magnetic, electronic, and optical applications. …”

“…The contents illustrate the rapid progress on molecular dynamics simulations in many fields of science and technology, such as nanotechnology, energy research, and biology, due to the advances of new dynamics theories and the extraordinary power of today's computers. …”

“…The deciphering of the genome and, last but not least, the development of modern sequencing methods make many people fear that their "individuality" could be lost as a result. …”