“…These neglected tropical disease (NTD) pathogens causes debilitating illnesses, which include hepatosplenomegaly, hepatic fibrosis, haemorrhagic necrotic ulcerations in the intestinal mucosa, urogenital tract diseases, in addition to cardiopulmonary, renal and neurologic lesions due to egg accumulation in the liver, intestines, uro-genital tissues and other sites. …”

“…There is a huge range of liver diseases and non-alcoholic fatty liver disease (NAFLD) is the most common chronic hepatic condition, which in some patients progresses to cirrhosis and liver cancer. …”

“…The prevalence of obesity and its comorbidities, particularly type 2 diabetes, cardiovascular and hepatic disease and certain cancers, continues to rise worldwide. …”

“…SARS-CoV-2 has also been causing pancreatic and hepatic injury. Emerging data have shown that COVID-19 patients continue to shed the virus into their stools, even when patients test negative for COVID-19 in pulmonary secretions. …”

“…Nonalcoholic fatty liver disease (NAFLD) is known as the hepatic manifestation of the metabolic syndrome, and while most patients develop simple steatosis, up to one-third can develop nonalcoholic steatohepatitis (NASH). …”

“…This is supported by the genome-wide view on VDR binding sites in human lymphocytes, monocytes, colon and hepatic cells. All genomic actions of 1a,25(OH)2D3 are mediated by the transcription factor vitamin D receptor (VDR) that has been the subject of intense study since the 1980’s. …”

“…Even more importantly, people with schistosomiasis are highly susceptible to malaria, tuberculosis and hepatic and acquired immunodeficiency viruses. There is only one drug, praziquantel, currently available for treatment and it has high efficacy, low cost, and limited side effects. …”

“….; rheumatoid arthritis, Bliddal et al.; Hepatitis C Virus and mixed cryoglobulinemia, Ferri et al.; and, psoriathic arthritis, Ruffilli et al.). …”

“…Utility values were derived from a cohort of men (average age 54 years) with decompensated cirrhosis resulting from chronic hepatitis B infection and measured with the Health Utility Index Mark 3 (HUI3) instrument. …”

“…El capítulo 8 destaca la importancia de las infecciones crónicas, como la hepatitis y la infección por el VIH, y el capítulo 9 analiza cómo pueden tratarse de forma segura las enfermedades neurológicas. …”
Acceso restringido usuarios UPSA
Información de ayuda para ClinicalKey

“…Terapia hormonal.24 Enfermedades neurodegenerativas.25 Depresión y otras enfermedades mentales.26 Epidemiología y prevención del suicidio.27 Causas externas de morbilidad y mortalidad,28 Enfermedades transmisibles: aspectos generales29 Vacunas e inmunización.30 Infecciones de transmisión sexual y VIH/SIDA.31 COVID-19.32 Tuberculosis, gripe, meningitis y legionelosis.33 Hepatitis virales, paludismo, dengue y fiebre Amarilla.34 Cólera, fiebre tifoidea y poliomielitis.35 Infecciones asociadas a la atención sanitaria.36 Intoxicaciones y toxiinfecciones alimentarias.37 Enfermedades infecciosas emergentes. …”

“…Some attention and progress appears to be focused on vaccines based on the M2 ectodomain (M2e) employing a variety of constructs, adjuvants and delivery systems, including M2e-hepatitis B core antigen, flagellin constructs, and virus-like particles (VLP). …”