Tabla de Contenidos: “…PHASE I STUDY OF FIAC IN BONE MARROW TRANSPLANT PATIENTS WITH HERPESGROUP VIRUS INFECTIONS -- Comment -- PHASE I ORAL DOSE RANGING FIAC STUDY IN IMMUNOCOMPROMISED PATIENTSWITH VZV AND HSV INFECTIONS -- Comment -- PHASE I/II TRIAL OF FIAC EFFICACY IN IMMUNOSUPPRESSED PATIENTS WITHVZV INFECTION -- Comment -- SUMMARY OF ALL THE FIAC CLINICAL STUDIES AT MSKC -- 5 Oclassen Clinical Trial R89-001-01 -- COMMENT -- 6 Oclassen Clinical Trial R90-001-01 (NIH Protocol 91-AI-0031) -- COMMENT -- 7 Oclassen Clinical Trial R91-001-10 (NIH Protocol 91-DK-AI-213) -- COMMENT -- 8 Eli Lilly Trial H3X-MC-PPPA -- UNIVERSITY OF TEXAS, GALVESTON SITE -- TUFTS NEW ENGLAND MEDICAL CENTER SITE -- 9 Eli Lilly Trial H3X-MC-PPPG -- COMMENT -- 10 Eli Lilly Trial H3X-MC-PPPC (NIH Protocol 93-DK-0031) -- AVAILABLE CLINICAL DATA REGARDING POTENTIAL TOXICITY -- AVAILABLE SAFETY DATA -- DEVELOPMENT OF PROTOCOL AND FDA REVIEW -- PATIENT SELECTION AND ENROLLMENT -- Inclusion Criteria -- Exclusion Criteria -- Re-enrollment -- Possible Adverse Effects -- Informed Consent -- CONDUCT OF STUDY -- STUDY OUTCOME -- Deaths -- Patient 2 -- Patient 1 -- Patient 4 -- Patient 6 -- Patient 7 -- Liver Transplantation -- Patient 3 -- Patient 10 -- Other Nonlethal Adverse Events -- Gastrointestinal side effects/pancreatitis -- Hepatoxicity -- Peripheral Neuropathy/Myopathy -- Fatigue -- No Adverse Events -- RESPONSE TO THE EMERGENCY -- LONG-TERM FOLLOW-UP -- CONCLUSIONS -- 11 Summary of Patient Interviews -- 12 Overall Assessment of the Trials -- PROCEDURAL REQUIREMENTS -- SUBSTANTIVE NORMS -- Favorable Balance of Harms and Benefits -- Equitable Selection of Subjects -- Compensation for Research-Related Injury -- Informed Consent -- SUMMARY -- 13 Recent Studies of FIAU Toxicity -- MECHANISMS -- ANIMAL MODELS -- Lilly Rat Studies -- Comments -- Cornell Woodchuck Studies -- Comments…”

Tabla de Contenidos: “…-- Farah Magrabi, Ibrahim Habli, Mark Sujan, David Wong, Harold Thimbleby, Maureen Baker, Enrico Coiera -- Technologies that transform: digital solutions for optimising medicines use in the NHS -- Stephen John Goundrey-Smith -- Communications -- Human factors challenges for the safe use of artificial intelligence in patient care -- Mark Sujan, Dominic Furniss, Kath Grundy, Howard Grundy, David Nelson, Matthew Elliott, Sean White, Ibrahim Habli, Nick Reynolds -- Recording problems and diagnoses in clinical care: developing guidance for healthcare professionals and system designers -- Anoop Dinesh Shah, Nicola J Quinn, Afzal Chaudhry, Ralph Sullivan, Julian Costello, Dermot O'Riordan, Jan Hoogewerf, Martin Orton, Lorraine Foley, Helene Feger, John G Williams -- Editorial -- Welcome to BMJ Health & Care Informatics -- Philip Scott -- Original Article -- Large retrospective analysis on frailty assessment in primary care: electronic Frailty Index versus frailty coding -- Pablo Millares-Martin -- Original Research -- Patient perceptions and interactions with their web portal-based laboratory results -- Sean Robinson, Melissa Reed, Travis Quevillon, Ed Hirvi -- Small interface changes have dramatic impacts: how mandatory fields in electronic medical records increased pertussis vaccination rates in Australian obstetric patients -- Roberto Orefice, Julie A Quinlivan -- Potential impact of data source and interoperability messaging on health information technology (HIT) users: a study series from the United States Department of Veterans Affairs -- Jennifer Herout, Donna Baggetta, Amanda Cournoyer, Aaron S Dietz, Jane Robbins, Kyle Maddox, Jolie Dobre -- Clinician preferences for computerised clinical decision support for medications in primary care: a focus group study -- Katy E Trinkley, Weston W Blakeslee, Daniel D Matlock, David P Kao, Amanda G Van Matre, Robert Harrison, Cynthia L Larson, Nic Kostman, Jennifer A Nelson, Chen-Tan Lin, Daniel C Malone -- Reliability of comorbidity scores derived from administrative data in the tertiary hospital intensive care setting: a cross-sectional study -- Michael Hua-Gen Li, Anastasia Hutchinson, Mark Tacey, Graeme Duke -- Conformity of Diabetes Mobile apps with the Chronic Care Model -- Raheleh Salari, Sharareh R Niakan Kalhori, Marjan Ghazisaeidi, Farhad Fatehi -- Digital innovation evaluation: user perceptions of innovation readiness, digital confidence, innovation adoption, user experience and behaviour change -- Tim Benson -- Dietitians can improve accuracy of prescribing by interacting with electronic prescribing systems -- Susan De Waal, Laurie Lucas, Simon Ball, Tanya Pankhurst -- Lessons learned from a comprehensive electronic patient record procurement process-implications for healthcare organisations -- W Priestman, R Collins, H Vigne, S Sridharan, L Seamer, D Bowen, N J Sebire -- Trend of intestinal infectious diseases recorded at a tertiary care hospital in India: an ICD-10 analysis -- P N Roopalekha Jathanna, Ramya Vijeta, Vinod R Jathanna -- Developing a telerehabilitation programme for postoperative recovery from knee surgery: specifications and requirements -- MReza Naeemabadi, Birthe Dinesen, Ole Kæseler Andersen, Niels Kragh Madsen, Ole Højgaard Simonsen, John Hansen -- Interventions to improve the use of EMRs in primary health care: a systematic review and meta-analysis -- Noura Hamade, Amanda Terry, Monali Malvankar-Mehta -- Web and mobile-based technologies for monitoring high-risk pregnancies -- Haleh Ayatollahi, Malihe Ghalandar Abadi, Morteza Hemmat -- Characteristics of patients with body mass index recorded within the Kent Integrated Dataset (KID) -- Zara Cuccu, Gerrard Abi-Aad, Allison Duggal -- Growth of health literacy research activity in three Middle Eastern countries -- Soheila Bazm, Reihaneh Bazm, Farzaneh Sardari -- Effectiveness of the eCARE programme: a short message service for asthma monitoring -- Lathy Prabhakaran, Yap Chun Wei -- Design and virtual implementation of a biomedical registry framework for the enhancement of clinical trials: colorectal cancer example -- Athanasios Kotoulas, George Lambrou, Dimitrios-Dionysios Koutsouris -- Coding and classifying GP data: the POLAR project -- Christopher Pearce, Adam McLeod, Jon Patrick, Jason Ferrigi, Michael Michael Bainbridge, Natalie Rinehart, Anna Fragkoudi -- Ontology to identify pregnant women in electronic health records: primary care sentinel network database study -- Harshana Liyanage, John Williams, Rachel Byford, Simon de Lusignan -- An intervention study to assess potential effect and user experience of an mHealth intervention to reduce sedentary behaviour among older office workers -- Simone Boerema, Lex van Velsen, Hermie Hermens -- Availability and usage of clinical decision support systems (CDSSs) in office-based primary care settings in the USA -- Xia Jing, Lina Himawan, Timothy Law -- NHS Scotland's Decision Support Platform: a formative qualitative evaluation -- Kathrin Cresswell, Margaret Callaghan, Hajar Mozaffar, Aziz Sheikh -- Two algorithms for the reorganisation of the problem list by organ system -- Daniel B Hier, Joshua Pearson -- Design and implementation of the stacked, synchronised and iconographic timeline-structured electronic patient record in a UK NHS Global Digital Exemplar hospital -- Alan Arthur Hales, David Cable, Eleanor Crossley, Callum Findlay, David Anthony Rew -- e-Therapies in England for stress, anxiety or depression: how are apps developed? …”