“…BACKGROUND: Cardiovascular disease (CVD) is the leading cause of mortality and morbidity in the United States. A 2016 review for the US Preventive Services Task Force (USPSTF) found statin therapy associated with decreased risk of all-cause and cardiovascular mortality and CVD events in adults at increased CVD risk but without prior CVD events. …”

“…PURPOSE: To review the evidence on benefits and harms of (1) screening children and adolescents for prediabetes and type 2 diabetes and (2) interventions for prediabetes or type 2 diabetes that was screen detected or recently diagnosed for populations and settings relevant to primary care in the United States. DATA SOURCES: PubMed/MEDLINE, the Cochrane Library, and trial registries through May 3, 2021; reference lists of retrieved articles; outside experts; and reviewers, with surveillance of the literature through July 22, 2022. …”