“…Multiple sclerosis (MS) offers important challenges to understanding its complex genetics and molecular and immunological mechanisms, which eventually lead to relapsing and progressive clinical forms and a constellation of clinical manifestations. …”

“…BACKGROUND: During routine clinical care, treatments are adaptive to patients' responses to previous treatment assignments. …”

“…Under its Evidence-based Practice Program, the Agency for Healthcare Research and Quality (AHRQ) is developing scientific information for other agencies and organizations on which to base clinical guidelines, performance measures, and other quality improvement tools. …”

“…" ... presents original articles of basic research interest regarding clinical questions at hand, as well as clinical studies in the field of otorhinolaryngology and related subdisciplines."…”