“…The evolution of health care is expanding the possibilities for integration of clinical research into the continuum of clinical care; new approaches are enabling the collection of data in real-world settings; and new modalities, such as digital health technologies and artificial intelligence applications, are being leveraged to overcome challenges and advance clinical research. …”

Tabla de Contenidos: “…Contents; Contributors; Foreword; Preface; Acknowledgments; SECTION I: Conceptual and Methodological Issues, Perspectives, and Directions in Clinical Practice and Research; SECTION II: Primary Higher-Order Mediators in Preventive Medicine and Mental Health: Predispositions, Psychophysiological Development, and Behavioral Tendencies; SECTION III: Select Disorders in Clinical and Health Psychology, Psychiatry, and Behavioral Medicine; SECTION IV: Select Interventions in Clinical Practice; SECTION V: Integrative Multimodal Assessment and Intervention; Index…”

Tabla de Contenidos: “…Clinical reasoning, critical thinking and the PPCP - introduction / Cary Mobley -- Ambulatory care - chronic pain management clinic / Robin Moorman Li -- Ambulatory care - geriatric care cardiology / Nicole Early and Elizabeth Pogge -- Ambulatory care - type 2 diabetes management / Bradley Phillips and Michelle Farland -- Ambulatory care - warfarin management clinic / Lihui Yuan -- Inpatient critical care - diabetic ketoacidosis / Carinda Feild -- Inpatient psychiatry care - treatment resistant schizophrenia / Ericka L. …”

“…This reprint considers a wide variety of topics concerning molecular and clinical advances in understanding early mammalian embryo development. …”

“…Health care delivery is shifting away from the clinic and into the home. Even prior to the COVID-19 pandemic, the use of telehealth, wearable sensors, ambient surveillance, and other products was on the rise. …”

Tabla de Contenidos: “…National Priorities for the Assessment of Clinical Conditions and Medical Technologies -- Copyright -- Acknowledgments -- Foreword -- Contents -- Summary -- ASSESSING MEDICAL PRACTICE -- A NATIONAL APPROACH -- PRIORITY-SETTING CRITERIA -- TWENTY ASSESSMENT PRIORITIES -- USING THE PRIORITIES -- ACCOMMODATING CLINICAL CONDITIONS AND TECHNOLOGIES -- NEXT STEPS -- 1 Introduction -- 2 A Pilot Process for Setting National Assessment Priorities -- ELEMENTS OF A NATIONAL APPROACH -- NATIONALLY APPLICABLE PRIORITY-SETTING CRITERIA -- Primary Criteria -- Potential (for an Assessment) to Improve Individual Patient Outcome -- Potential to Affect a Large Patient Population -- Potential to Reduce Unit or Aggregate Cost -- Potential to Reduce Unexplained Variations in Medical Practice -- Secondary Criteria -- Potential to Address Social and Ethical Implications -- Potential to Advance Medical Knowledge -- Potential to Affect Policy Decisions -- Potential to Enhance the National Capacity for Assessment -- Potential to Be Readily Conducted -- A CONCEPTUAL FRAMEWORK FOR PRIORITIES -- The Clinical Condition Approach -- The Technology Approach -- Integrating the Clinical Condition and Technology Approaches -- METHOD OF THIS PILOT STUDY -- Overview -- Round I of the Modified Delphi Process -- Round II of the Modified Delphi Process -- The Priority-Setting Group's Meeting -- Activities Following the Priority-Setting Meeting -- 3 Twenty Priority Assessment Areas -- CLINICAL CONDITIONS -- Breast Cancer -- Improve Individual Patient Outcome -- Affect a Large Patient Population -- Reduce Unit or Aggregate Cost -- Reduce Unexplained Variations in Medical Practice -- Advance Medical Knowledge -- Affect Policy Decisions -- Cataracts -- Improve Individual Patient Outcome -- Affect a Large Patient Population -- Reduce Unit or Aggregate Cost…”

Tabla de Contenidos: “…Clinical Applications of Mifepristone (RU 486) and Other Antiprogestins -- Copyright -- Preface -- Contents -- Summary -- CROSS-CUTTING RECOMMENDATIONS -- USES OF ANTIPROGESTINS: THE REPRODUCTIVE CYCLE -- Contraception -- Post-Coital Contraception -- Menses Induction -- Pregnancy Termination During the First Trimester -- Pregnancy Termination During the Second Trimester -- Cervical Ripening -- Labor Induction in Late Pregnancy -- OTHER POTENTIAL THERAPEUTIC USES OF ANTIPROGESTINS -- Endometriosis -- Uterine Leiomyomas (Fibroids) -- Breast Cancer -- Meningioma -- ANTIGLUCOCORTICOID EFFECTS OF ANTIPROGESTINS -- 1 Introduction -- BACKGROUND AND HISTORICAL PERSPECTIVES -- Finding an Antiprogestin -- THE IOM REPORT -- CROSS-CUTTING RECOMMENDATIONS -- REFERENCES -- 2 Uses of Antiprogestins: The Reproductive Cycle (Part I) -- CONTRACEPTION -- POST-COITAL CONTRACEPTION -- MENSES INDUCTION -- REFERENCES -- 3 Uses of Antiprogestins: The Reproductive Cycle (Part II) -- PREGNANCY TERMINATION DURING THE FIRST TRIMESTER -- Health Services Research -- PREGNANCY TERMINATION DURING THE SECOND TRIMESTER -- CERVICAL RIPENING -- LABOR INDUCTION IN LATE PREGNANCY -- Fetal Demise -- SUMMARY -- REFERENCES -- 4 Other Therapeutic Uses of Antiprogestins -- ENDOMETRIOSIS -- Utility of Mifepristone (RU 486) for Treatment of Endometriosis -- Summary -- UTERINE LEIOMYOMAS (FIBROIDS) -- Utility of Mifepristone for Treatment of Uterine Leiomyomas -- BREAST CANCER -- Mechanism of Action -- Clinical Issues -- Adjuvant Therapy and Chemoprevention -- Resistance -- Dose Issues -- Conclusions -- MENINGIOMAS -- Conclusions -- REFERENCES -- 5 Antiglucocorticoid Effects of Antiprogestins -- GLUCOCORTICOID FUNCTION -- THERAPEUTIC USE OF MIFEPRISTONE (RU 486) AS ANANTIGLUCOCORTICOID -- ADVERSE ANTIGLUCOCORTICOID EFFECTS OF ANTIPROGESTINS -- REFERENCES…”

“…Artificial intelligence and machine learning for the data quality of clinical trial studies…”