Tabla de Contenidos: “…Hazard Identification of Chemical Mixtures -- Indication of Bioavailability of Chemicals at Hazardous-Waste Sites -- Water-Quality Monitoring -- Indicators of Air Pollution -- Risk Characterization of Species Under Study -- Dose-Response Relationships -- Contamination of Human Food Chain -- IN SITU STUDIES -- Fish -- Planarians -- Starlings -- Earthworms -- Honey Bees -- SUMMARY -- 6 Animal Sentinels in Risk Assessment -- USE OF ANIMAL SENTINEL SYSTEMS IN EXPOSURE ASSESSMENT -- Animals as General Environmental Monitors -- Animals as Monitors of Their Own Exposure -- Animals as Monitors of Exposure of Their Consumers -- Animals as Surrogate Monitors of Human Exposure -- USE OF ANIMAL SENTINEL SYSTEMS IN HAZARD IDENTIFICATION -- Early Warnings: Initial Identification of Hazardous Agents -- Hazard Identification for Chemical Mixtures -- USE OF ANIMAL SENTINEL SYSTEMS IN DOSE-RESPONSE ASSESSMENT -- USE OF ANIMAL SENTINEL SYSTEMS IN RISK CHARACTERIZATION -- Risks to Animal Species Under Study -- Risk to Consumers of Animal Species Under Study -- Risk to Humans: Animal Sentinels as Surrogates -- USE OF ANIMAL SENTINEL SYSTEMS IN RISK MANAGEMENT -- Management of Risks to Animal Species Under Study -- Management of Risks to Consumers of Animal Species Under Study -- Management of Risks to Human Health: Animal Sentinels as Surrogates -- Animal Sentinel Systems as Monitors of Effectiveness of Risk Management Actions -- SUMMARY -- 7 Selection and Application of Animal Sentinel Systems in Risk Assessment -- SYSTEM DESIGN -- IMPLEMENTATION -- VALIDATION -- PROGRAM INTEGRATION -- 8 Conclusions and Recommendations -- References -- Appendix Workshop Participants…”

Tabla de Contenidos: “…Cover; Contents; Author Biographies; Chapter Summaries; Preface; Part I: Key Concepts; Chapter 1 - Parenting - An Introduction; Chapter 2 - The Social Context of Parenting; Chapter 3 - Parenting in Social and Economic Adversity; Chapter 4 - Parenting Across the Lifespan; Chapter 5 - Parental Influences on Vulnerability and Resilience; Chapter 6 - Parenting in Culturally Divergent Settings; Chapter 7 - Religious Influences on Parenting; Chapter 8 - Parenting in Reconstituted and Surrogate Families; Chapter 9 - Sexual Orientation and Parenting…”

Tabla de Contenidos: “…Chapter 3 PresentationFrom People to Presentation; 3.1 Presenting Textual Documents; Documents, chapters, sections; Unstructured text documents; Page images; Images with text; Realistic books; 3.2 Presenting Multimedia Documents; Sound and pictures; Video; Music; 3.3 Document Surrogates; Metadata; Multimedia surrogates; 3.4 Searching; Types of queries; Case-folding and stemming; Phrase searching; Query interfaces; Searching multimedia; Searching music; Searching images; 3.5 Metadata Browsing; Lists; Dates; Hierarchies; Facets; 3.6 Putting It All Together; An institutional repository…”

Tabla de Contenidos: “…About the Editors vii -- Complexity Science in Human Change: Research, Models, Clinical Applications 1 -- Human Synchronization Maps-The Hybrid Consciousness of the Embodied Mind 7 -- Four Methods to Distinguish between Fractal Dimensions in Time Series through Recurrence Quantification Analysis 15 -- Cross-Correlation- and Entropy-Based Measures of Movement Synchrony: Non-Convergence of Measures Leads to Different Associations with Depressive Symptoms 29 -- Catastrophe Theory Applied to Neuropsychological Data: Nonlinear Effects of Depression on Financial Capacity in Amnestic Mild Cognitive Impairment and Dementia 51 -- Dynamics of Remote Communication: Movement Coordination inVideo-Mediated and Face-to-Face Conversations 65 -- Changes in the Complexity of Limb Movements during the First Year of Life across Different Tasks 83 -- A Dynamical Autocatalytic Network Model of Therapeutic Change 97 -- Studying Physiological Synchrony in Couple Therapy through Partial Directed Coherence: Associations with the Therapeutic Alliance and Meaning Construction 117 -- Recurrence-Based Synchronization Analysis of Weakly Coupled Bursting Neurons under External ELF Fields 135 -- Alternate Entropy Computations by Applying Recurrence Matrix Masking 153 -- Affect-Logic, Embodiment, Synergetics, and the Free Energy Principle: New Approaches to the Understanding and Treatment of Schizophrenia 171 -- Clients' Emotional Experiences Tied to Therapist-Led (but Not Client-Led) Physiological Synchrony during Imagery Rescripting 185 -- Affective Saturation Index: A Lexical Measure of Affect 195 -- Beyond Dyadic Coupling: The Method of Multivariate Surrogate Synchrony (mv-SUSY) 221.…”

“…Among the initiatives considered are promoting the decision-making autonomy of patients/clients and their surrogates, enhancing the quality of care and quality of life available to long term care residents, and providing fair compensation for injured victims when serious harm occurs. …”

Tabla de Contenidos: “…A Worked-out Example of Surrogate-based Bayesian Parameter and Field Identification Methods -- 8.1 Introduction -- 8.2 Numerical modelling of seabed displacement -- 8.2.1 The deterministic computation of seabed displacements -- 8.2.2 Modified probabilistic formulation -- 8.3 Surrogate modelling -- 8.3.1 Computation of the surrogate by orthogonal projection -- 8.3.2 Computation of statistics -- 8.3.3 Validating surrogate models -- 8.4 Efficient representation of random fields…”

“…Reporter proteins are valid surrogates for direct detection of infected cells in vitro and in vivo, without the use of secondary methodologies to identify infected cells. …”

Tabla de Contenidos: “…Before the empire : the Bible as a marginal and a minority text : -- India : liturgical and iconic usage -- China : the surrogate Bible : monuments and manuscripts -- Africa : Latin Bible and local controversies -- Part II. …”
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Tabla de Contenidos: “…Epistemological vertigo and allegory: thoughts on massacres, actual, surrogate, and averted - Beersheba, Wake in Fright, Australia. …”

Tabla de Contenidos: “…Frontmatter -- On the Series -- Contents -- 1 Locating the Global: Articulations, Encounters, and Interactions -- 2 A Forgotten Emporium: Commercial Aspirations and Transnational Mercantile Networks in Seventeenth- Century Glückstadt -- 3 Global Materials, Contact Zones, and Imitation: The Making of Metal Commodities in Eighteenth-Century Sweden -- 4 Coffee and Coffee Surrogates in Sweden: A Local, Global, and Material History -- 5 Circulating Heterodox Medicine: Globalizing and Localizing Naturopathy in Interwar Finland -- 6 Stocktaking at Christiansborg: Metals and Slaves in the Danish Atlantic Trade at the Mid-Eighteenth Century -- 7 Copper on the Move: A Commodity Chain between Sweden and France, 1720–1790 -- 8 Encountering Mid-Eighteenth Century Morocco from Below: Slavery, Race, and Religion in two Scandinavian Captivity Narratives -- 9 Eurafrican Mobility and Encounters with Race, ca. 1880–1920 -- 10 Muslim Scholars Living in Three Worlds: West African Muslims and the Imposition of the European Colonial Order -- 11 Russia in the Global Parliamentary Moment, 1905–1918: Between a Subaltern Empire and an Empire of Subalterns -- 12 A Neutral Place? …”

Tabla de Contenidos: “…Cover -- Half Title -- Series -- Title -- Copyright -- Contents -- About the Editors -- List of Contributors -- Chapter 1 A Comprehensive Research Look on Opportunities and Challenges in Advanced Wireless Communication -- Chapter 2 Opportunities and Challenges in Advanced Wireless Communication -- Chapter 3 Millimetre Wave for Next-Generation Networks: Opportunities, Challenges, and Possible Solutions -- Chapter 4 Cognitive Radio: A Key Enabling Technology for 5G and Beyond Communication -- Chapter 5 Device-to-Device Communication: Cooperative Device-to-Device Communication -- Chapter 6 UAV-Assisted Communication: Unmanned Aerial Vehicles in Vehicle-to-Everything Communication Networks -- Chapter 7 A Flight from 5G to 6G with UAV-Enabled Communications: A Case Study -- Chapter 8 Development and Analysis of an RF-Powered Rechargeable Wireless Sensor Network for LR-WPAN -- Chapter 9 Cooperative NOMA with Hybrid PTS-Based Energy Harvesting Relay -- Chapter 10 Full-Duplex Energy Harvesting-Based Cooperative NOMA Network -- Chapter 11 Design of Efficient Signal Detection Schemes for Large-Scale MU-MIMO System -- Chapter 12 Flexible Antennas - A New Frontier in 5G Technology: A Review -- Chapter 13 Flexible MIMO Antennas for UWB Applications -- Chapter 14 Design of Inset-Fed Microstrip Patch Antenna Using Surrogate Model-Assisted Differential Evolution -- Chapter 15 Millimetre Wave Antenna Design for 5G Applications -- Chapter 16 Machine Learning Algorithms for Optimization and Intelligence in Wireless Networks: WSNs, MANETs, VANETs, and USNs -- Chapter 17 An Efficient Localization for Resource Management in UAV-Assisted Wireless Networks Using Deep Learning -- Chapter 18 A Smartphone-Based Context-Aware Driver Rating System for Cities in Developing Economies -- Index…”

Tabla de Contenidos: “…Intro -- Title page -- Front matter -- Reviewers -- In Memoriam -- Acknowledgments -- Contents -- Boxes, Figures, and Tables -- Acronyms and Abbreviations -- Proceedings of a Workshop -- Background on Drug Development and Regulatory Review -- Type of FDA Drug Development and Approval Pathways -- Ethical Requirements of Clinical Research -- Exploring the Challenges with Traditional Clinical Development -- Inefficiences and Long Development Timelines -- Generalizability of Clinical Trial Results to Clinical Practice -- Appropriate Use of Biomarkers and Surrogate Endpoints -- Finding the Right Dose -- New Strategies in Oncology Drug Development -- Patient-Centered Drug Development -- Informed Consent -- Patient Risk -- Mechanism-Informed Cancer Drug Development -- Targeting Mutations in Breast Cancer -- Targeting the Microenvironment in Multiple Myeloma -- Fictional Imaging -- New Endpoints -- Modeling -- Process Modeling the Drug Development Pathway -- Dosage Modeling -- Modeling Benefits and Risks -- Development and Use of Biomarkers in Cancer Clinical Trials -- Innovative Clinical Trial Designs -- Adaptive Designs -- Seamless (Continuous) Clinical Trial Designs -- Master Protocols -- Clinical Trials with Common Control Arms -- Issues to Consider with Innovative Clinical Trial Designs -- Leveraging Real-World Evidence from Clinical Practice -- Pragmatic Trials -- Using EHR Data in Studies -- When to Use Real-World Evidence -- Standardization -- Guidance on Standardizing and Using Real-World Evidence -- Patient Privacy -- Expanding Clinical Trial Eligibility -- Collaboration -- Potential Policy Opportunities -- Innovations at CMS -- FDA Oncology Center of Excellence -- Expanded Access -- Cancer Moonshot -- Examples of Innovations in Cancer Drug Development -- Development of Crizotinib -- Development of Avelumab -- Development of Pembrolizumab…”

Tabla de Contenidos: “…Primary Clients, Secondary Clients, Surrogate Clients and Non-clients: The Expanding Duty of Care of Scottish Solicitors / Kenneth Swinton --18. …”

Tabla de Contenidos: “…Bussiere and Barbara Mounho -- Relevant immune tests across different species and surrogate models / Jeanine L. Bussiere -- Antidrug antibody responses in nonclinical studies and their implications / Barbara Mounho -- Pharmacological immunogenicity and adverse responses to vaccines / Mary Kate Hart, Mark Bolanowski, and Robert V. …”

Tabla de Contenidos: “…Respect for Autonomy -- The Nature of Autonomy -- The Capacity for Autonomous Choice -- The Meaning and Justification of Informed Consent -- Disclosure -- Understanding -- Voluntariness -- A Framework of Standards for Surrogate Decision-Making -- Conclusion -- 4. Nonmaleficence -- The Concept of Nonmaleficence -- Distinctions and Rules Governing Nontreatment -- Optional Treatments and Obligatory Treatments -- Killing and Letting Die -- The Justification of Intentionally Arranged Deaths -- Protecting Incompetent Patients -- Conclusion -- 5. …”

Tabla de Contenidos: “…Orphans and Incentives: Developing Technologies to Address Emerging Infections -- Copyright -- Preface -- THE FORUM -- THE TOPIC -- THE REPORT AND ITS ORGANIZATION -- ACKNOWLEDGMENTS -- NOTES -- Contents -- Summary -- LESSONS -- Introduction -- BACKGROUND -- THE WORKSHOP -- Workshop Summary -- THE CHILDREN'S VACCINE INITIATIVE* -- A Brief History -- Defining and Implementing Cross-Sectoral Collaboration -- Defining, Creating, and Stabilizing the Market -- Situation Analysis -- Market Segmentation -- Centralized Procurement -- Tiered Pricing -- Intellectual Property and Its Protection -- Technology Transfer -- Individual Product Experiences -- A More Heat-Stable Polio Vaccine -- The Hepatitis B Vaccine -- OTHER MODELS* -- The Malaria Vaccine Development Board -- The International AIDS Vaccine Initiative (IAVI) -- AN INDUSTRY PERSPECTIVE ON THE EMERGING INFECTIONS AGENDA* -- Industry's Response to HIV/AIDS -- The Emerging Infections Scenario and HIV/AIDS -- Barriers -- LEGAL AND REGULATORY ISSUES* -- Accelerated Approval and Development of Drugs for Serious and Life-Threatening Illnesses -- Clinical Studies -- Surrogate Endpoints -- Restricted Distribution and the Matter of Antimicrobial Resistance -- Product Labeling -- Product Availability -- International Harmonization of Technical Requirements to Register Pharmaceuticals -- Intellectual Property Rights Revisited -- Orphan Drug Legislation -- PUBLIC-SECTOR AGENDAS AND PRIORITIES* -- LESSONS LEARNED AND ISSUES FOR RESOLUTION -- Lessons from the Children's Vaccine Initiative -- Divergent Sectoral Mandates and Notions of Risk -- The Product Life Cycle and the Role of Market Analysis -- Authentic Collaboration -- The Pivotal Roles of Advocacy and Public Information -- Issues for Resolution -- Agendas and Priorities -- Funding -- Multi-Tiered Pricing -- Restricted Distribution -- Surrogate Endpoints…”

Tabla de Contenidos: “…AFTERWARD -- Subsequent Events -- Current Procedures and Challenges -- REFERENCES -- 5 Donor Screening and Deferral -- INTRODUCTION -- Critical Events -- Critical Event 1 -- Critical Event 2 -- Explanatory Hypotheses -- DONOR SCREENING PRACTICES -- Hepatitis -- Donor Pools -- Early Donor Screening Practices -- ANALYSIS AND FINDINGS -- January 4, 1983, CDC Meeting -- Outcomes of the Meeting -- Donor Questioning and Opposition to It -- Surrogate Testing and Opposition to It -- Criticism of the CDC's Data and Motives -- Risk Assessment -- Lack of Leadership -- Conclusions -- December 1983 Blood Products Advisory Committee Meeting -- Interim Local Efforts to Screen Aggressively -- Reliability of Surrogate Tests -- Task Force Report on Surrogate Testing -- Comment on the Blood Products Advisory Committee -- Informing the Public -- AIDS Politics -- CONCLUSIONS -- Hypothesis One -- Hypothesis Two -- Political Factors -- Ideological Factors -- Organizational Factors -- Historical Factors -- AFTERWORD -- Donor Screening 1985-1995 -- HIV -- Hepatitis -- HTLV-I and HTLV-II -- Current Donor Screening Procedures -- Current Infectious Risk Through Blood Transfusion -- REFERENCES -- 6 Regulations and Recall -- INTRODUCTION -- FRAMEWORK OF ANALYSIS -- Critical Events -- Critical Event 1 -- Critical Event 2 -- Critical Event 3 -- Critical Event 4 -- FDA Regulatory Authority and Practice -- Explanatory Hypotheses -- FINDINGS AND CONCLUSIONS -- FDA Letters of March 1983 -- Analysis -- Summary and Conclusions -- Nonautomatic Recalls -- Analysis -- Summary and Conclusions -- Heat-Treated AHF Concentrate and the FDA's Recall Policy -- Analysis -- Summary and Conclusions -- Lookback and Notification of Individuals Transfused with Contaminated Blood Products -- Analysis -- Summary and Conclusions -- INFLUENCE AND RESPONSIBILITIES OF OTHER ORGANIZATIONS…”

Tabla de Contenidos: “…Social Snacking and Shielding: Using Social Symbols, Selves, and Surrogates in the Service of Belonging Needs…”

Tabla de Contenidos: “…; Digital and analog differences; Digital images as surrogates; Digital cameras and scanners; Dynamic range and bit depth; Resolution; Resolution recommendations; Master and derivative files; Interpolation; Compression; File formats; Digital decisive moment; 3 Photographic image issues; Introduction; Visual literacy; Authenticity; Decontexualization; Paradigm shift; Contextual meaning; Photography in context; Intellectual property rights…”

Tabla de Contenidos: “…""PARTICIPATION IN SERIES OTHER THAN THE SELECTION SERIES""""6 The Referent Cohort ""; ""7 Exposure Definition and Measurement ""; ""DNA-PROVIDED DOSE ESTIMATES""; ""Individual Doses""; ""Alternative Uses of Dose Data""; ""POTENTIAL SURROGATE MEASURES OF DOSE""; ""DECISIONS FOR THE ANALYSES IN THIS REPORT""; ""FUTURE OPTIONS FOR USE OF DOSIMETRY""; ""8 Mortality Ascertainment ""; ""FACT-OF-DEATH ASCERTAINMENT""; ""FACT-OF-DEATH VALIDATION""; ""DATE OF DEATH""; ""CAUSE-OF-DEATH ACQUISITION""; ""CAUSE-OF-DEATH VALIDATION""; ""9 Analysis Structure ""; ""OVERVIEW""; ""AVAILABLE DATA""…”