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12261Publicado 2010Tabla de Contenidos: “…-- Building Modules -- Installing Modules -- Generating Module Dependencies -- Loading Modules -- Managing Configuration Options -- Module Parameters -- Exported Symbols -- The Device Model -- Kobjects -- Ktypes -- Ksets -- Interrelation of Kobjects, Ktypes, and Ksets -- Managing and Manipulating Kobjects -- Reference Counts -- sysfs -- Adding and Removing kobjects from sysfs -- Adding Files to sysfs -- The Kernel Events Layer -- Conclusion -- 18 Debugging -- Getting Started -- Bugs in the Kernel -- Debugging by Printing -- Robustness -- Loglevels -- The Log Buffer -- syslogd and klogd -- Transposing printf() and printk() -- Oops -- ksymoops -- kallsyms -- Kernel Debugging Options -- Asserting Bugs and Dumping Information -- Magic SysRq Key -- The Saga of a Kernel Debugger -- gdb -- kgdb -- Poking and Probing the System -- Using UID as a Conditional -- Using Condition Variables -- Using Statistics -- Rate and Occurrence Limiting Your Debugging -- Binary Searching to Find the Culprit Change -- Binary Searching with Git -- When All Else Fails: The Community -- Conclusion -- 19 Portability -- Portable Operating Systems -- History of Portability in Linux -- Word Size and Data Types -- Opaque Types -- Special Types -- Explicitly Sized Types -- Signedness of Chars…”
Libro electrónico -
12262Publicado 2015Tabla de Contenidos: “…The Three Important Ingredients -- The Business Process Reengineering Cycle -- Methods and Approaches to Business Process Reengineering -- Business Process Reengineering Project and Success Criteria -- The Pros of Business Process Reengineering -- The Cons of Business Process Reengineering -- Conclusion -- TOTAL QUALITY MANAGEMENT -- Introduction -- Implementing Total Quality Management in the Organization -- Key Elements for Change -- The Use of Total Quality Management in Process Work -- TOOLS FOR TQM -- House of Quality or Quality Function Deployment -- Taguchi Techniques -- Pareto Diagrams -- Process Diagrams -- Cause & -- Effect Analysis Diagrams -- Statistical Process Control -- The PDCA Cycle -- Business Excellence and EFQM -- Conclusion -- SIX SIGMA -- Introduction -- What Six Sigma Means -- The Purpose of Six Sigma -- DMAIC -- DMADV -- Conclusion -- End Notes -- 4: What Is Business Process Management? …”
Libro electrónico -
12263por Ranganatham, M.Tabla de Contenidos: “…Savings Bank Account with Commercial Banks -- Bank Fixed Deposits -- Company Fixed Deposits -- Post Office Deposits and Certificates -- Life Insurance Policies -- Provident Fund Scheme -- Equity Linked Savings Schemes (ELSSs) -- Pension Plan -- Government and Semi-government Securities -- Mutual Fund Schemes -- Real Assets -- Real Estate -- Bullion Investment -- Investment Opportunities for Foreign Citizens of Indian Origin -- Foreign Direct Investment -- Portfolio Investment -- Sources of Investment Information -- Institutions Floating Financial Securities -- Financial Markets -- Financial Service Intermediaries -- Media -- Summary -- Concepts -- Short Questions -- Essay Questions -- Appendix I -- Appendix II -- Chapter 6: Debt Instruments and Their Valuation -- Players in the Debt Market -- Valuation of Debt Instruments -- Running Yield -- Simple Yield to Maturity -- Redemption Yield -- Holding Period Yield -- Comparison of Yield Computations -- Yields to Call/Put -- Yields on Index Linked Bonds -- Yield Curves -- Ascending Yield Curve -- Descending Yield Curve -- Risk Management in Bonds -- Default Risk -- Reinvestment Risk -- Purchasing Power Risk -- Price Risk -- Liquidity Risk -- Bond Duration -- Convexity -- Dispersion -- Summary -- Concepts -- Short Questions -- Essay Questions -- Problems -- Case Study -- Chapter 7: Equity Instruments and Their Valuation -- Share Valuation -- Earnings Valuation -- Negative Earnings Due to Cyclical Nature of Industry -- Negative Earning Due to Unforeseeable Circumstances -- Negative Earning Due to Poor Managements -- Persistent Negative Earnings -- Negative Earnings Due to Early Growth Stage -- Negative Earnings Due to High Leverage Cost -- Earnings Forecast -- Forecasting Earnings Using Statistical Tools -- Forecast of Annual Versus Quarterly results -- Revenues Valuation -- Cash Flows Valuation…”
Publicado 2005
Libro electrónico -
12264Publicado 2012Tabla de Contenidos: “…Storing FILESTREAM Data -- Contained Databases -- Altering a Table -- Adding or Dropping a New Column -- Modifying Column Properties -- Adding or Removing Integrity Constraints -- Enabling or Disabling Constraints -- Renaming Tables and Other Database Objects -- Removing Database Objects -- Summary -- Exercises -- Chapter 6: Queries -- SELECT Statement: Its Clauses and Functions -- WHERE Clause -- Boolean Operators -- IN and BETWEEN Operators -- Queries Involving NULL Values -- GROUP BY Clause -- Aggregate Functions -- Convenient Aggregate Functions -- Statistical Aggregate Functions -- User-Defined Aggregate Functions -- HAVING Clause -- ORDER BY Clause -- Using ORDER BY to Support Paging -- SELECT Statement and IDENTITY Property -- CREATE SEQUENCE Statement -- Set Operators -- UNION Set Operator -- INTERSECT and EXCEPT Set Operators -- CASE Expressions -- Subqueries -- Subqueries and Comparison Operators -- Subqueries and the IN Operator -- Subqueries and ANY and ALL Operators -- Temporary Tables -- Join Operator -- Two Syntax Forms to Implement Joins -- Natural Join -- Joining More Than Two Tables -- Cartesian Product -- Outer Join -- Further Forms of Join Operations -- Theta Join -- Self-Join, or Joining a Table with Itself -- Semi-Join -- Correlated Subqueries -- Subqueries and the EXISTS Function -- Should You Use Joins or Subqueries? …”
Libro electrónico -
12265Publicado 2022Tabla de Contenidos: “…Design Specifications For Low-Level Opacity Monitors -- OPACITY MONITOR INSTRUMENT DESIGN -- Beam Splitter Techniques -- Optical Density/Opacity Calculations -- Stack-Exit Correlation -- Calibration Filter Selection -- Combiner Equations -- Opacity-Mass Correlations -- OPACITY MONITOR PERFORMANCE SPECIFICATIONS -- Installation Requirements -- Field Audit Performance Tests -- Opacity Monitor Quality Assurance -- Quality Assurance Plan -- Daily Zero and Upscale Calibration Drift Test -- Quarterly Audit - Three-Point Calibration Error Test -- Annual Primary Zero Alignment -- Corrective Maintenance and Diagnostic Tests -- REFERENCES -- BIBLIOGRAPHY -- CHAPTER 9 CONTINUOUS PARTICULATE MONITORING -- REGULATORY SPECIFICATIONS -- CALIBRATING PARTICULATE MATTER CEMS (PM CEMS) -- Reference Method Tests -- Statistical Analysis Procedures -- Issues Associated with the Correlation Method -- CONTINUOUS PARAMETER MONITORING SYSTEMS (PM CPMS) -- Determining the Operating Limit (Case A) -- Determining the Operating Limit (Case B) -- BAG LEAK DETECTORS (BLD) -- ALTERNATIVE CALIBRATION METHODS -- Generating Reference Samples -- Mass References -- Particle Size Standards -- PARTICULATE MEASUREMENT TECHNIQUES -- Accumulated Mass Sensors -- Optical Sensors -- Hybrid (Combination) Systems -- Monitoring in Wet Stacks -- Probe Electrification Methods - Triboelectric Devices Applied for Bag Leak Detection -- Choosing a PM System -- PM CEMS QUALITY ASSURANCE - REQUIREMENTS FOR CONTINIUING OPERATION -- The Quality Assurance/Quality Control Manual -- Routine Checks -- Quarterly Audits -- PM Correlation Audits -- DEVELOPMENTS IN PM CEMS -- CHAPTER 10 CEM SYSTEM CONTROL, DATA ACQUISITION, AND REPORTING -- CONTROL SYSTEMS -- Computer Control -- Programmable Logic Controllers -- Data Loggers -- Embedded Microprocessors -- THE DAHS COMPUTER -- CEM System Software Development…”
Libro electrónico -
12266Publicado 2023Tabla de Contenidos: “…. -- See also -- Chapter 5: Easily Performing Statistical Tests Using Linear Models -- Technical requirements -- Further information -- Modeling data with a linear model -- Getting ready -- How to do it... -- How it works... -- There's more... -- Using a linear model to compare the mean of two groups -- Getting ready -- How to do it... -- How it works... -- There's more... -- Using a linear model and ANOVA to compare multiple groups in a single variable -- Getting ready -- How to do it... -- How it works... -- There's more... -- Using linear models and ANOVA to compare multiple groups in multiple variables -- Getting ready -- How to do it... -- How it works... -- Testing and accounting for interactions between variables in linear models -- Getting ready -- How to do it... -- How it works... -- Doing tests for differences in data in two categorical variables -- Getting ready -- How to do it... -- How it works... -- Making predictions using linear models -- Getting ready -- How to do it... -- How it works... -- See also -- Chapter 6: Performing Quantitative RNA-seq -- Technical requirements -- Further information -- Estimating differential expression with edgeR -- Getting ready -- How to do it... -- How it works... -- Estimating differential expression with DESeq2 -- Getting ready -- How to do it... -- How it works... -- There's more... -- Estimating differential expression with Kallisto and Sleuth -- Getting ready -- How to do it... -- How it works... -- Using Sleuth to analyze time course experiments -- Getting ready -- How to do it... -- How it works... -- Analyzing splice variants with SGSeq -- Getting ready…”
Libro electrónico -
12267Publicado 2024Tabla de Contenidos: “…Poisoning-assisted inference -- Attack scenarios -- Mitigations -- Example attribute inference attack -- Membership inference attacks -- Statistical thresholds for ML leaks -- Label-only data transferring attack -- Blind membership inference attacks -- White box attacks -- Attack scenarios -- Mitigations -- Example membership inference attack using the ART -- Summary -- Chapter 10: Privacy-Preserving AI -- Privacy-preserving ML and AI -- Simple data anonymization -- Advanced anonymization -- K-anonymity -- Anonymization and geolocation data -- Anonymizing rich media -- Differential privacy (DP) -- Federated learning (FL) -- Split learning -- Advanced encryption options for privacy-preserving ML -- Secure multi-party computation (secure MPC) -- Homomorphic encryption -- Advanced ML encryption techniques in practice -- Applying privacy-preserving ML techniques -- Summary -- Part 4: Generative AI and Adversarial Attacks -- Chapter 11: Generative AI - A New Frontier -- A brief introduction to generative AI -- A brief history of the evolution of generative AI -- Generative AI technologies -- Using GANs -- Developing a GAN from scratch -- WGANs and custom loss functions -- Using pre-trained GANs -- Pix2Pix -- CycleGAN -- Pix2PixHD -- Progressive Growing of GANs (PGGAN) -- BigGAN -- StarGAN v2 -- StyleGAN series -- Summary -- Chapter 12: Weaponizing GANs for Deepfakes and Adversarial Attacks -- Use of GANs for deepfakes and deepfake detection -- Using StyleGAN to generate convincing fake images -- Creating simple deepfakes with GANs using existing images -- Making direct changes to an existing image -- Using Pix2PixHD to synthesize images -- Fake videos and animations -- Other AI deepfake technologies -- Voice deepfakes -- Deepfake detection -- Using GANs in cyberattacks and offensive security -- Evading face verification…”
Libro electrónico -
12268por Saleem, ShaikhTabla de Contenidos: “…Net National Product (NNP) -- National Income or National Income at Factor Cost (NI) -- Personal Income (PI) -- Disposable Income (DI) -- National Income Estimates in India -- National Income After Independence -- NIC and CSO Estimates -- Methodology of National Income Estimation in India -- Net-product Method -- Net-income Method -- State of the Economy -- Per Capita Income and Consumption -- Economic Growth -- Sectoral Contribution -- Aggregate Demand -- Savings and Investments -- Savings -- Investments -- Trends in National Income Growth and Structure -- Sectoral Investment and ICOR -- Consumption Basket -- Inclusive Growth -- Inflation -- Causes for the Slow Growth of National Income in India -- Suggestions to Raise the Level and Growth Rate of National Income in India -- Major Features of National Income in India -- Difficulties or Limitations in the Estimation of National Income in India -- Key Words -- Questions -- References -- Chapter 8: Foreign Trade Policy and Balance of Payments -- Foreign Trade Policy and Balance of Payments -- Main Features of India's Trade Policy -- Phases of India's Trade Policy -- India's Foreign Trade Policy, 1991 -- Rationale of Foreign Trade Policy -- Major Trade Reforms -- Assessment of the New Trade Policy -- Balance of Payments (BoPs) -- Current Account Deficit (CAD) -- Capital Account Deficit -- Other Non-debt Flows -- Key Words -- Questions -- References -- Chapter 9: Poverty in India -- Concept, Meaning, and Definition of Poverty -- People Living Under Poverty Line -- Causes of Poverty in India -- The Developmentalist View -- The Neoliberal View -- Historical Trends in Poverty Statistics -- Poverty and Inclusive Growth -- Consumption Patterns Below and Above PL -- Trends in Consumption Growth (Rural-Urban Disparity) -- Factors Responsible for Poverty -- Measures to Reduce Poverty…”
Publicado 2011
Libro electrónico -
12269
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12270
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12271
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12272por Virtanen, TuomasTabla de Contenidos: “…4.2.1 DFT-Based Analysis Synthesis with Perfect Reconstruction 55 -- 4.2.2 Probability Distributions for Speech and Noise DFT Coefficients 57 -- 4.3 Voice Activity Detection 58 -- 4.3.1 VAD Design Principles 58 -- 4.3.2 Evaluation of VAD Performance 62 -- 4.3.3 Evaluation in the Context of ASR 62 -- 4.4 Noise Power Spectrum Estimation 65 -- 4.4.1 Smoothing Techniques 65 -- 4.4.2 Histogram and GMM Noise Estimation Methods 67 -- 4.4.3 Minimum Statistics Noise Power Estimation 67 -- 4.4.4 MMSE Noise Power Estimation 68 -- 4.4.5 Estimation of the A Priori Signal-to-Noise Ratio 69 -- 4.5 Adaptive Filters for Signal Enhancement 71 -- 4.5.1 Spectral Subtraction 71 -- 4.5.2 Nonlinear Spectral Subtraction 73 -- 4.5.3 Wiener Filtering 74 -- 4.5.4 The ETSI Advanced Front End 75 -- 4.5.5 Nonlinear MMSE Estimators 75 -- 4.6 ASR Performance 80 -- 4.7 Conclusions 81 -- References 82 -- 5 Extraction of Speech from Mixture Signals 87 / Paris Smaragdis -- 5.1 The Problem with Mixtures 87 -- 5.2 Multichannel Mixtures 88 -- 5.2.1 Basic Problem Formulation 88 -- 5.2.2 Convolutive Mixtures 92 -- 5.3 Single-Channel Mixtures 98 -- 5.3.1 Problem Formulation 98 -- 5.3.2 Learning Sound Models 100 -- 5.3.3 Separation by Spectrogram Factorization 101 -- 5.3.4 Dealing with Unknown Sounds 105 -- 5.4 Variations and Extensions 107 -- 5.5 Conclusions 107 -- References 107 -- 6 Microphone Arrays 109 / John McDonough, Kenichi Kumatani -- 6.1 Speaker Tracking 110 -- 6.2 Conventional Microphone Arrays 113 -- 6.3 Conventional Adaptive Beamforming Algorithms 120 -- 6.3.1 Minimum Variance Distortionless Response Beamformer 120 -- 6.3.2 Noise Field Models 122 -- 6.3.3 Subband Analysis and Synthesis 123 -- 6.3.4 Beamforming Performance Criteria 126 -- 6.3.5 Generalized Sidelobe Canceller Implementation 129 -- 6.3.6 Recursive Implementation of the GSC 130 -- 6.3.7 Other Conventional GSC Beamformers 131 -- 6.3.8 Beamforming based on Higher Order Statistics 132 -- 6.3.9 Online Implementation 136 -- 6.3.10 Speech-Recognition Experiments 140.…”
Publicado 2012
Biblioteca Universitat Ramon Llull (Otras Fuentes: Universidad Loyola - Universidad Loyola Granada, Biblioteca de la Universidad Pontificia de Salamanca)Libro electrónico -
12273Simulation of Spray Polymerisation and Structure Generation in Spray Drying by Single Droplet ModelsPublicado 2022Tabla de Contenidos: “…40 -- 3 Modelling of Reactive Droplet Drying and Polymerisation 41 -- 3.1 Transport in a Reaction-Diffusion System 42 -- 3.1.1 Constant Physical Properties. 44 -- 3.1.2 Consideration of Mixture Effects . 46 -- 3.1.3 Diffusion and Reaction Driven Convection at Variable -- Molar Weights47 -- 3.1.4 Transport of Polymer - Quasi-Steady-State Assumption . 50 -- 3.1.5 Transport of Statistical Moments . 52 -- 3.2 Lumped Modelling - 0D approach 56 -- 3.2.1 General Equations for Reactive Spray Drying57 -- 3.2.2 Spray Polymerisation - Quasi-Steady-State Assumption 58 -- 3.2.3 Spray Polymerisation - Method of Moments. 59 -- 3.3 Distributed Modelling - 1D approach. 60 -- 3.3.1 General Equations of the Droplet Continuum60 -- 3.3.2 Boundary Conditions . 62 -- 3.3.3 Spray Polymerisation - QSSA66 -- 3.3.4 Spray Polymerisation - Method of Moments. 68 -- 3.4 Comparison with Existing Models 69 -- 3.5 Implementational Considerations . 70 -- 3.5.1 Implementation of the Moving Boundary Problem . 70 -- 3.5.2 Boundary Conditions . 71 -- 3.5.3 Treatment of Convection Terms . 72 -- 3.5.4 Implementation of Diffusion. 75 -- 3.6 Verification of the Transport Approach76 -- 3.6.1 Diffusion Driven Convection, Constant Properties 76 -- 3.6.2 Diffusion Driven Convection, Variable Molar Weight 79 -- 3.6.3 Diffusion Driven Convection, Excess Volumes . 82 -- 3.6.4 Reaction Induced Convection85 -- 4 Simulation of Spray Polymerisation 87 -- 4.1 Kinetics and Process Conditions . 88 -- 4.2 Lumped Simulation of Droplet Polymerisation 92 -- 4.2.1 Principle Course of the Process - -- Plain Kinetics, no Monomer Evaporation 92 -- 4.2.2 Effects of Kinetics on the Process 94 -- 4.3 Spatial Effects in Droplet Polymerisation 98 -- 4.3.1 Effect of the Diffusion Coefficient on Concentration Gradients . 99 -- 4.3.2 Inhomogeneities of the Product at Small Diffusion Coefficients, Effect of Moments' Diffusion . 102 -- 4.3.3 Effect of Monomer Evaporation . 106 -- 4.3.4 Pre-polymerisation Before Atomisation . 111 -- 4.3.5 Polymerisation at Elevated Monomer Content in the Drying Gas 116 -- 4.3.6 Influence of Non-Ideality of Activities 122 -- 4.3.7 Interaction with the drying gas125 -- 4.3.8 Applicability of the QSSA model 131 -- 4.4 Summary of Basic Findings on Droplet Polymerisation . 133 -- 4.5 Process Evaluation, Numerical DoEs. 135 -- 4.5.1 DoEs' Setup and Evaluation. 135 -- 4.5.2 Droplet Polymerisation with Solvent in the Feed 138 -- 4.5.3 Bulk Polymerisation within a Droplet 142 -- 4.5.4 Bulk Feed with Pre-Polymerisation before Atomisation . 149 -- 4.6 Discussion and Suggestions for Further Research 153 -- 5 SPH and its Application to Single Droplet Slurry Drying 155 -- 5.1 Mathematical Derivation . 156 -- 5.1.1 SPH Interpolation 156 -- 5.1.2 Integral Approximations . 159 -- 5.1.3 First Derivatives . 160 -- 5.1.4 Laplace-Operator and Divergence of Diffusive Fluxes 162 -- 5.1.5 General Second Derivatives. 165 -- 5.1.6 Choice of Kernel, Smoothing Length and Cut-off Radius 165 -- 5.1.7 Correction of the SPH Approximation 168 -- 5.2 Implementation of Boundary Conditions . 169 -- 5.2.1 Ghost Particles169 -- 5.2.2 Insertion of Boundary Conditions into SPH Equations . 171 -- 5.2.3 Repulsive Forces as Hard Sphere Boundaries172 -- 5.3 Hydrodynamics of an Incompressible Liquid in SPH173 -- 5.3.1 Continuity Equation, Density Evaluation 173 -- 5.3.2 Momentum Balance . 175 -- 5.3.3 Weakly Compressible SPH 178 -- 5.4 Incompressible SPH 179 -- 5.4.1 Boundary Conditions in ISPH182 -- 5.4.2 Boundaries by the Ghost Technique, Wall Boundaries 182 -- 5.4.3 Free Surface Boundaries in ISPH 183 -- 5.4.4 Modifications to ISPH in This Work . 184 -- 5.5 Surface Tension and Wetting . 189 -- 5.5.1 The Interparticle Force Approach 190 -- 5.5.2 The Concept of Surface-Lateral Particle Forces . 195 -- 5.6 Representation of the Solid Phase 200 -- 5.6.1 Primary Particles in the Slurry200 -- 5.6.2 Calculation of Crust Formation . 202 -- 5.7 Modelling of Drying Phenomena in SPH . 205 -- 5.7.1 Heat Conduction . 205 -- 5.7.2 Implementation of Linear Driving Force based Heat and -- Mass Transfer into SPH . 205 -- 5.7.3 Extension to the Second Drying Period . 208 -- 5.7.4 Treatment of Evaporation Concerning Particle Mass and -- Deletion 209 -- 5.7.5 Modelling of Diffusion Driven Drying Involving the Gas -- Phase . 210 -- 5.8 Time Integration 213 -- 5.8.1 Stability Criteria in Explicit Time Stepping. 214 -- 5.8.2 Time Stepping Criteria Employed in This Work and Their -- Reference Length . 216 -- 5.8.3 Implicit Solution of Diffusive Equations . 218 -- 5.8.4 Initialisation of an SPH Calculation . 220 -- 6 Validation of the SPH Implementation 221 -- 6.1 Implicit Solution of Heat Conduction. 221 -- 6.2 Heat and Mass Transfer by Linear Driving Forces 224 -- 6.2.1 Heat Transfer to a Unilaterally Heated Rod. 224 -- 6.2.2 Coupled Heat and Mass Transfer: Droplet Evaporation . 226 -- 6.3 Diffusion Driven Drying by SPH-Grid Coupling . 228 -- 6.4 SPH Flow Solver . 230 -- 6.4.1 ISPH Solution of a Standing Water Column. 230 -- 6.4.2 Free Surface Flow 231 -- 6.4.3 Surface Tension Approach of Pairwise Forces234 -- 6.4.4 Wetting Phenomena . 237 -- 7 Simulation of Structure Evolution During Drying 243 -- 7.1 Simulation of the First Drying Period243 -- 7.2 Simulation of Crust Formation 245 -- 7.2.1 Simulation of the Second Drying Period without Crust -- Formation . 245 -- 7.2.2 Crust Formation by Caught on First Touch. 247 -- 7.2.3 Crust Formation Determined by the Water Content . 249 -- 7.2.4 Effect of the Density Correction . 250 -- 7.3 Influence of Adjustable Parameters on the Structure. 251 -- 7.4 Effect of the Temperature . 256 -- 7.5 Variation of the Resolution 259 -- 7.6 Drying of a Microporous Structure 261 -- 7.7 Comments on numerical efficiency 267 -- 8 Conclusion 269 -- A Numerical Regression by Gaussian Processes 273 -- B FVM Implementation of the Droplet Polymerisation Model 277 -- C Implementational Aspects of SPH 281 -- C.1 Neighbourhood Search281 -- C.1.1 Linked List 281 -- C.1.2 Verlet List . 282 -- C.2 Performance Aspects, Memory Alignment 282.…”
Libro electrónico -
12274
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12275
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12276
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12277por Leipzig, Jeremy“…The user will learn how the R environment works with R packages as well as its own capabilities in statistical analysis. We will be accessing spatial data in several formats-html, xml, shapefiles, and text-locally and over the web to produce a map of home foreclosure auctions and perform statistical analysis on these events…”
Publicado 2009
Libro electrónico -
12278
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12279
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12280Publicado 2013Tabla de Contenidos: “…Pharmaceutical Applications of Hydrophilic Interaction Chromatography 4.1 Introduction 4.1.1 Definition of the problem 4.1.2 Selection of conditions 4.1.3 Validation of the method 4.1.4 General references 4.2 Determination of Counterions 4.2.1 Salt selection and options for counterion determination 4.2.2 Specific counterion analysis 4.2.3 Counterion screening with gradient elution 4.2.4 Suitable reference standards for counterion analysis 4.3 Main Component Methods 4.3.1 Potency/assay methods 4.3.2 Equipment cleaning verification assays 4.3.3 Dissolution methods 4.4 Determination of Impurities 4.4.1 Impurity screening and orthogonal separations 4.4.2 Impurity identification 4.4.3 Specific impurity determination 4.4.3.1 Pyrimidines, purines, nucleosides 4.4.3.2 Hydrazines with ethanol as weak solvent 4.4.3.3 Neutral and charged polar impurities in a drug substance 4.4.3.4 Polar basic compounds and impurities 4.4.4 Statistical design of experiments (DOE) for optimization 4.5 Excipients 4.5.1 Parenteral and solution formulations 4.5.2 Tablets, capsules and inhalation products 4.5.3 Sugars 4.5.4 Stabilizers and antioxidants 4.6 Chiral Applications 4.6.1 Chiral selectors and HILIC 4.6.1.1 Cyclodextrins 4.6.1.2 Macrocyclic antibiotics 4.6.1.3 Chiral crown ethers 4.6.1.4 Cyclofructans 4.6.2 Conclusions for chiral separations 4.7 Conclusions Chapter 5. …”
Biblioteca Universitat Ramon Llull (Otras Fuentes: Universidad Loyola - Universidad Loyola Granada, Biblioteca de la Universidad Pontificia de Salamanca)Libro electrónico