“…The report examines the nature of risks and uncertainty associated with different types of PPP project and the practical consequences of transferring risks to private partners. …”

Acceso restringido usuarios UPSA

Acceso restringido usuarios UPSA

“…By evaluating the various health risks related to exposure to swimming pools, spas, and surface waters, this Special Issue seeks to address the proper management of waters used for recreational purposes, both in natural and built environments. …”

“…The mechanism of arsenic-induced toxicology, involving arsenic interaction with critical thiols in proteins and the health risks associated with exposure to arsenic, is also discussed…”

“…Nonetheless, the idiosyncratic risks that group structures bring about may require particular attention be paid to the governance of corporate groups. …”

“…When crisis has seriously undermined performance, leaders have embraced reform to shore up legitimacy, while in good times they have tended to disagree over the long-term risks of reform and how to deal with those risks ..…”

“…Beyond anecdotes: run the numbers with one of the world's leading investment researchers and top-ranked business school professors Guidance on understanding the real opportunities and not-so-obvious risks associated with each strategy--and instruction on how to mitigate the risks…”

“…As the price of Bitcoin and other cryptocurrencies continue to fluctuate and news stories of cryptocurrency hackers increase, investors have to be more conscious of the huge opportunities and large risks in this market. Understanding these risks and rewards of cryptocurrency is vital for everyone wanting to make money on this exciting new form of investing. …”

Tabla de Contenidos: “…3.2 Interim Conclusion -- 4 A Critical Outlook on Assumptions-Decision Systems in Transformation Towards Sustainability -- 4.1 Actors -- 4.2 Issues -- 4.3 Structures -- 4.4 Processes -- 4.5 Outcomes -- 4.6 Interim Conclusion -- 5 Knowledge Diplomacy as Facilitator of Transformation Towards Sustainability-The "New Diplomacy" and Consensual Knowledge -- 5.1 Knowledge Diplomacy and Consensual Knowledge -- 5.2 Negotiation Perspectives on Consensual Knowledge -- 5.2.1 Power-Based Perspective on Consensual Knowledge -- 5.2.2 Systems Perspective on Consensual Knowledge -- 5.3 Case Study: The IPCC and the Generation of Consensual Knowledge for Climate Negotiations -- 5.4 Interim Conclusion: Convergence of Knowledge Frameworks as Opportunities and Risks-The Preceding Step Towards Global Convergence -- 6 The Systems Perspective on the Transformation Towards Sustainability -- 6.1 System Transformation and Human Cognition-Power and Identities -- 6.2 System Transformation-'Grasping' the Context of Sustainable, Low-Carbon Transformation -- 6.3 Transition, Transformation and Leapfrogging-Sustainable Low Carbon Policy Priorities in Countries with Emerging Economies -- 6.3.1 Leapfrogging of the Developing Countries-A Way Forward? …”

Tabla de Contenidos: “…-- 16.3.1 Example 1: Terri's International Bulbs -- 16.3.2 Example 2: Martin's Theme Parks -- 16.3.3 Example 3: Pat's Fruity Clothing -- 16.3.4 Know the details of the business -- 16.4 Understanding risk and reward -- 16.5 Further reading -- 16.6 Action items -- 17 Be a better decision-maker -- 17.1 Deciding who decides: Decision-making frameworks -- 17.2 Deciding what to do: OKRs, rocks, and pebbles…”

Tabla de Contenidos: “…3.4.1 Electrokinetics‐Enhanced In Situ Chemical Oxidation (EK‐ISCO) -- 3.4.2 Electro‐Fenton -- 3.5 In Situ Chemical Reduction (ISCR) -- 3.6 Challenges for Upscaling -- 3.7 Concluding Remarks -- References -- Chapter 4 The Electrokinetic Recovery of Tungsten and Removal of Arsenic from Mining Secondary Resources: The Case of the Panasqueira Mine -- 4.1 Introduction -- 4.2 Tungsten Mining Resources: The Panasqueira Mine -- 4.2.1 The Development of the Industry -- 4.2.2 Ore Extraction Processes -- 4.2.3 Potential Risks -- 4.3 The Circular Economy of Tungsten Mining Waste -- 4.3.1 Panasqueira Old Slimes vs. …”

Tabla de Contenidos: “…Predicting event counts for patients at risk -- 9.3.1. Global prediction -- 9.4. Predicting event counts accounting for ongoing recruitment -- 9.4.1. …”

Tabla de Contenidos: “…4 - Therapeutic Nanoparticles Loaded by Electrospray -- 4.1 - Single Needle EHDA Processing -- 4.1.1 - Particles -- 4.1.2 - Aerosols -- 4.1.3 - Porous particles -- 4.2 - Two-Needle Coaxial Electrospray -- 4.2.1 - Capsules -- 4.2.2 - Bubble particles -- 4.2.3 - Porous particles -- 4.2.4 - Hollow particles -- 4.3 - Multicapillary Electrospray -- 5 - Conclusions -- References -- Chapter 7 - Nanoformulation and administration of PUFA-rich systems for applications in modern healthcare -- 1 - Introduction -- 2 - Lipid Nanoparticles: Types and Fabrication Technology -- 2.1 - Nanoencapsulation -- 2.2 - Liposomes -- 2.3 - Nanocochleates -- 2.4 - Nanodispersions -- 2.5 - Micelles -- 2.6 - Nanoemulsions -- 2.7 - Multilayer Nanoemulsions -- 2.8 - Filled Hydrogel Particles -- 2.9 - Solid-Lipid Nanoparticles -- 2.10 - Nanostructured Lipid Carriers -- 3 - Understanding the Physiological System for Therapy: The Significance of Lipid Nanotechnology at Tissue and Cellular Level -- 3.1 - The Potential of Nanoparticles for Targeted Action at Tissue Level -- 3.1.1 - The gastrointestinal barrier -- 3.1.2 - The blood-brain barrier -- 3.2 - The Facets of Nanoparticle Play at Cellular Level -- 4 - Therapeutic Lipid Nanostructures -- 4.1 - For the Delivery of PUFAs -- 4.2 - Nanostructures for Cardiovascular Disease Treatment -- 4.3 - Nanostructures in Neurodegenerative Disease Treatment -- 4.4 - Nanostructures in Diabetes Management -- 4.5 - Nanostructures for Cancer Treatment -- 4.6 - Nanostructures for Infectious Diseases Treatment -- 4.7 - Nanostructures in Overcoming Proinflammatory Conditions -- 5 - Risk and Hazard Assessment -- 5.1 - Organic Solvents for Fabrication -- 5.2 - Potentially Hazardous Stabilizers and Surfactants -- 5.3 - Encapsulating Polymers -- 6 - Challenges and Scope -- 7 - Conclusions -- Acknowledgments -- References…”

Tabla de Contenidos: “…4.2.5.2 Under Uncertainty: Several Targets and Dynamic Appraisal -- 4.2.6 The Turning Point from Strategic Kaizen to Kaikaku -- 4.2.7 KAIZENshiro Budgets to Support Annual Takt Profit -- 4.2.7.1 Planning, Resourcing, Budgeting, and Execution -- 4.2.7.2 KAIZENshiro Budgets Integrated into Master Budget -- 4.2.8 Practice of Strategic Kaizen Target Setting -- 4.2.9 Deliverables and Completion Criteria: Feasible Strategic Kaizen Alternatives and KAIZENshiro Budget -- 4.3 Fourth Process: Annual Operational Reconciliation -- 4.3.1 Summary of the Annual Operational Expectations -- 4.3.2 Target Production Time in Practice: From Annual Takt Profit to Module Synchronization -- 4.3.3 Operational Catchball -- 4.3.3.1 Top-Down and Bottom-Up -- 4.3.3.2 Inside-Out and Outside-In -- 4.3.4 Products and Modules with Deficiencies -- 4.3.5 Developing Balanced Scorecard and KPIs -- 4.3.6 Deliverables and Completion Criteria: Balanced Scorecard and Annual Operational Strategic Kaizen -- 4.4 Fifth Process: Organizing, Planning, and Learning for Strategic Kaizen -- 4.4.1 Annual Strategic Kaizen Organization -- 4.4.1.1 The Seven Strategic Kaizen Organization Principles -- 4.4.1.2 Establishing Holistic and Synergistic Effects of Strategic Kaizen Organization -- 4.4.1.3 Allocated Ownership for all Strategic Kaizen KPIs at All Levels -- 4.4.1.4 Allocate Ownership for all Strategic Kaizen Projects -- 4.4.2 Feedforward Control -- 4.4.2.1 Visual Management for Strategic Kaizen -- 4.4.2.2 Strategic Kaizen Meetings -- 4.4.2.3 Review Mechanism: Risks and Uncertainties -- 4.4.2.4 The Process of Personal Reviews and of Recognition Systems -- 4.4.3 Planning for Strategic Kaizen -- 4.4.3.1 The Five Steps to Strategic Kaizen Action Plan and Monitoring -- 4.4.3.2 Definition and Preparation of Individual Plans -- 4.4.4 Learning for Strategic Kaizen…”

Tabla de Contenidos: “…-- 1.4.2 Prerequisites -- 1.4.3 Postrequisites -- 1.5 Getting Started -- 1.6 Key Success Factors for Systems Engineers in Reliability, Maintainability, and Supportability Engineering -- 1.6.1 Customer-Supplier Relationships -- 1.6.2 Language and Clarity of Communication -- 1.6.3 Statistical Thinking -- 1.7 Organizing a Course Using this Book -- 1.7.1 Examples -- 1.7.2 Exercises -- 1.7.3 References -- 1.8 Chapter Summary -- References -- Chapter 2 Reliability Requirements -- 2.1 What to Expect from this Chapter -- 2.2 Reliability for Systems Engineers -- 2.2.1 "Reliability" in Conversation -- 2.2.2 "Reliability" in Engineering -- 2.2.3 Foundational Concepts -- 2.2.4 Reliability Concepts for Systems Engineers -- 2.2.5 Definition of Reliability -- 2.2.6 Failure Modes, Failure Mechanisms, and Failure Causes -- 2.2.7 The Stress-Strength Model -- 2.2.8 The Competing Risk Model -- 2.3 Reliability, Maintainability, and Supportability are Mutually Reinforcing -- 2.3.1 Introduction -- 2.3.2 Mutual Reinforcement -- 2.4 The Structure of Reliability Requirements -- 2.4.1 Reliability Effectiveness Criteria -- 2.4.2 Reliability Figures of Merit -- 2.4.3 Quantitative Reliability Requirements Frameworks…”

Tabla de Contenidos: “…-- 2.3.1 The Standards-Making Process of OMG -- 2.3.2 The History of UML -- 2.4 Modeling -- 2.4.1 What Kind of Modeling -- 2.4.2 Purposes for UML Modeling -- 2.4.2.1 Analysis -- 2.4.2.2 Design -- 2.4.2.3 Implementation -- 2.4.2.4 Communication -- 2.4.3 Principles of Modeling -- 2.4.3.1 Risk Mitigation -- 2.4.3.2 Information Hiding and Simplicity -- 2.4.3.3 Whole-Part Relationships -- 2.4.3.4 Classification and Generalization -- 3 Questions for Chapter 2 -- Answers for Chapter 2 -- 4 The Organization of UML -- 4.1 The UML 2.5 Specification -- 4.1.1 Target Audience -- 4.1.2 The Document Layout -- 4.2 The Language Definition-The Clauses -- 4.3 The Subclauses -- 4.4 The Abstract Syntax -- 4.5 The Layered Metamodel -- 4.6 Diagrams -- 4.6.1 Structure Diagrams -- 4.6.2 Behavior Diagrams…”

Tabla de Contenidos: “…5.3 Evolution of Network Security Strategies -- 5.4 Different Evolving Security Approaches -- 5.4.1 Conventional Approaches -- 5.4.2 Confidentiality Approaches -- 5.4.3 Privacy Approaches -- 5.4.4 Availability Approaches -- 5.4.5 Modern Approaches -- 5.5 Discussion -- 5.6 Conclusion -- References -- Chapter 6 The State of CDNs Today and What AI-Assisted CDN Means for the Future -- 6.1 Introduction -- 6.2 CDN and Its Challenges -- 6.2.1 Replica Server Placement -- 6.2.2 Content Replication -- 6.2.3 Request Routing -- 6.2.4 Load Balancing -- 6.3 Importance of AI in CDN -- 6.4 Pandemic and CDN -- 6.5 Security Threats in CDN -- 6.6 Conclusion -- References -- Chapter 7 Challenges and Opportunities in Smart City Network Management Through Blockchain and Cloud Computing -- 7.1 Introduction -- 7.2 Literature Review -- 7.2.1 Smart City and Network Management -- 7.2.2 Blockchain and Network -- 7.3 Blockchain and Smart City -- 7.3.1 Smart Healthcare -- 7.3.2 Smart E-Voting -- 7.3.3 Smart Logistics and Supply Chains -- 7.4 Cloud Computing and Challenges -- 7.4.1 Cloud Computing -- 7.5 Research Methodology -- 7.6 Conclusion -- References -- Chapter 8 Role of IoT in Smart Homes and Offices -- 8.1 Introduction -- 8.2 Smart Building Constituents -- 8.3 Concept of Smart Office Service Devices -- 8.4 IoT in Smart Homes and Offices -- 8.4.1 Smart Environment Models -- 8.4.2 IoT Control Systems for Smart Home Devices -- 8.4.3 Prevailing Designs in Smart Homes -- 8.4.4 Smart Home Constituents -- 8.4.5 Cloud Topological Structure -- 8.4.6 Smart Home-Based Cloud Architectural Design -- 8.5 Future Research Directions and Limitations of Smart Home-Based Technology -- 8.6 Conclusion -- References -- Chapter 9 Role of IoT in the Prevention of COVID-19 -- 9.1 Introduction -- 9.2 A Modern Era Problem -- 9.2.1 Current Risk -- 9.2.2 Awareness by Social Media…”

Tabla de Contenidos: “…12.5.1 Role of AI, ML, and Bioinformatics in Clinical Research -- 12.5.2 Role of AI and ML in Clinical Study Protocol Optimization -- 12.5.3 Role of AI and ML in the Management of Clinical Trial Participants -- 12.5.4 Role of AI and ML in Clinical Trial Data Collection and Management -- 12.6 Way Forward -- 12.7 Conclusion -- References -- Part III: Bioinformatics Tools for Healthcare Sector -- Chapter 13 Artificial Intelligence and Machine Learning in Healthcare Sector -- Abbreviations -- 13.1 Introduction -- 13.2 The Exponential Rise of AI/ML Solutions in Healthcare -- 13.3 AI/ML Healthcare Solutions for Doctors -- 13.4 AI/ML Solution for Patients -- 13.5 AI Solutions for Administrators -- 13.6 Factors Affecting the AI/ML Implementation in the Healthcare Sector -- 13.6.1 High Cost -- 13.6.2 Lack of Creativity -- 13.6.3 Errors Potentially Harming Patients -- 13.6.4 Privacy Issues -- 13.6.5 Increase in Unemployment -- 13.6.6 Lack of Ethics -- 13.6.7 Promotes a Less-Effort Culture Among Human Workers -- 13.7 AI/ML Based Healthcare Start-Ups -- 13.8 Opportunities and Risks for Future -- 13.8.1 Patient Mobility Monitoring -- 13.8.2 Clinical Trials for Drug Development -- 13.8.3 Quality of Electronic Health Records (EHR) -- 13.8.4 Robot-Assisted Surgery -- 13.9 Conclusion and Perspectives -- References -- Chapter 14 Role of Artificial Intelligence in Machine Learning for Diagnosis and Radiotherapy -- Abbreviations -- 14.1 Introduction -- 14.2 Machine Learning Algorithm Models -- 14.2.1 Supervised Learning -- 14.2.2 Unsupervised Learning -- 14.2.3 Semi-Supervised Learning -- 14.2.4 Reinforcement Learning (RL) -- 14.3 Artificial Learning in Radiology -- 14.3.1 Types of Radiation Therapy -- 14.3.1.1 External Radiation Therapy -- 14.3.1.2 Internal Radiation Therapy -- 14.3.1.3 Systemic Radiation Therapy -- 14.3.2 Mechanism of Action…”