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Tabla de Contenidos: “…Drinking Water and Health -- Copyright -- Contents -- Preface -- Historical Note -- Importance of Water Filtration -- Chlorination, The Most Significant Advance in Water Treatment -- Summary -- REFERENCES -- I Approach to the Study -- INTRODUCTION -- WATER CONSUMPTION -- RISK AND SAFETY -- MICROBIOLOGICAL CONTAMINANTS -- PARTICULATE CONTAMINANTS -- INORGANIC SOLUTES -- ORGANIC SOLUTES -- RADIOACTIVE CONTAMINANTS -- SUSCEPTIBLE SUBGROUPS AND OTHER CONSIDERATIONS -- REFERENCES -- II Chemical Contaminants: Safety And Risk Assessment -- EFFECTS ON HEALTH -- Reversibility of Chemical Injury -- Perspectives and Perceptions of Effects -- Irreversible (Self-Propagating) Effects -- Nonreversible Effects -- Reversible Effects -- IRREVERSIBLE TOXICITY -- Summary of Principles for Extrapolating Animal Toxicity To Humans -- The General Problem of Extrapolation -- Specific Problems in Extrapolation -- Size of Animals -- Number of Animals -- Environmental Differences -- Absorption -- Distribution and Storage -- Metabolic Differences -- Excretion and Reabsorption -- Differences in Receptor Sites -- Design of Laboratory Experiments on Animals -- Current Capability to Extrapolate -- THRESHOLDS -- Biological Considerations -- Consideration of the Dose-Response Relationship -- Examination of Experimental Dose-Response Curves -- Heterogeneity of the Population -- Statistical Considerations -- HIGH-DOSE TO LOW-DOSE EXTRAPOLATION -- Dose-Response Models -- Appropriateness of Data for Low-Dose Extrapolation -- INTERACTIONS -- SUMMARY-CHEMICAL CONTAMINANTS: SAFETY AND RISK ASSESSMENT -- Principle 1 -- Effects in Animals, Properly Qualified, are Applicable to Man -- Principle 2 -- Methods do not Now Exist to Establish a Threshold for Long-Term Effects of Toxic Agents -- Principle 3.…”

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Materias:

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“…IARC monographs on the evaluation of carcinogenic risks to humans…”

“…Analysis of APC mutations to perform prophylactic colectomy in subjects at risk for colorectal cancer…”
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“…Economic evaluation of drug eluting stents for high risk indications…”

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“…International Yearbook on Psychosocial Risks Prevention and Quality of Life at Work : new strategies on prevention of psychosocial risks at work : comparatives experiences…”

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Enlace del recurso

Materias: Enlace del recurso

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Materias: “…Risk Assessment…”

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Materias: “…Quality Control, Reliability, Safety and Risk…”