“…However, its involvement has been shown in various pathologies including ischemia-reperfusion injury and hereditary angioedema. Unexpected roles for the classical pathway have also been discovered recently, linked to both physiological and pathological aspects of development, including brain and cancer cells. …”

“…Key Features: Contains extensively revised and updated content throughout, while maintaining the same practical, easy-to-use format as the previous edition.Covers benign and malignant gastrointestinal diseases not often included in other texts, as well as in-depth discussions of pathophysiologic processes and molecular mechanisms wherever possible.Features more than 3,000 high-quality illustrations, including gross and microscopic photographs (many new to this edition), electron micrographs, radiographs, and line drawings.Includes separate chapters on hereditary polyposis, cancer syndromes, motility disorders, and inflammatory bowel disease, as well as neuroendocrine, hematopoeitic, and mesenchymal neoplasms. …”