Tabla de Contenidos: “…Introduction and overview -- Exploring the current landscape of central nervous system gene-targeted therapies -- Gene-targeted therapy approaches for central nervous system disorders : opportunities and challenges -- Translating gene-targeted therapies from bench to bedside -- Meaningful engagement of patients and families -- Future directions in the development of gene-targeted therapies -- Appendixes…”

Materias:

“…In the natural sciences topics ranging from the genetic engineering of microorganisms to produce antibiotics, the gene targeting and transformation in plants, the generation of marker-free plants in response to biosafety concerns, as well as the generation of transgenic animals and those derived through cloning are covered. …”

Tabla de Contenidos: “…EXECUTIVE SUMMARY -- SCIENTIFIC SUMMARY -- OPENING SPEECHES BY HOST COUNTRY -- INTRODUCTION -- Gene targeting: an historical perspective by M. Capecchi, United States -- Somatic gene therapy: from basic science to clinical applications by S. …”

“…It includes methods towards gene targeting, developing disease and pest resistant plants, creating temperature sensitive molecular machines, understanding mitochondrial mutagenesis, detecting anti-mutagens, improving genetic insight into impaired immunity and disease. …”

Tabla de Contenidos: “…Preface -- Section 1 Introduction -- Chapter 1 Introductory Chapter: CRISPR Technology by Yuan-Chuan Chen -- Chapter 2 Emerging CRISPR Technologies by Annelise Cassidy and Stephane Pelletier -- Section 2 Technology -- Chapter 3 Maximizing the Efficacy of CRISPR/Cas Homology-Directed Repair Gene Targeting by Terry S. Elton, Md. Ismail Hossain, Jessika Carvajal-Moreno, Xinyi Wang, Dalton J. …”

Tabla de Contenidos: “…26 Intracellular Signaling and Gene Target Analysis - Methods ChapterIndex…”

“…In search of more successful approaches, the pharmaceutical industry is moving towards phenotypic screening beyond individual genes/targets. However, this requires rethinking of diseases and drug discovery approaches from a network and systems biology perspective. …”

“…Based on the findings from the tenth paper, it is interesting to identify common gene targets between Glossina p. gambiensis and Glossina m. morsitans that might shed some lights as a suitable candidate for controlling both acute and chronic forms of sleeping sickness. …”