Mostrando 1,441 - 1,460 Resultados de 2,075 Para Buscar '"Damage"', tiempo de consulta: 0.10s Limitar resultados
  1. 1441
    Publicado 2015
    Tabla de Contenidos: “…s problem""; ""Brand you: social media jihad collateral damage""; ""Is your organisation at risk?""; ""Where to source information and support for crisis communications planning""…”
    Libro electrónico
  2. 1442
    Publicado 2014
    Tabla de Contenidos:
    Libro electrónico
  3. 1443
    Publicado 2017
    Tabla de Contenidos: “…Cover -- Title Page -- Copyright -- Contents -- Acknowledgments -- Part I: The Disaggregated World -- Chapter 1: The 10X Effect: Performance Multipliers to Achieve Lasting Success and Fulfillment -- The Origin of This Book at McKinsey and Harvard -- What This Book Is For and How It's Unique -- How This Book Is Organized -- Chapter 2: Giving Way to the New: The Boundaryless Twenty‐First‐Century Work Environment -- Fluidity of People -- Fluidity of Roles -- Fluidity of Information -- Chapter 3: Myths of Happiness and Leadership: Making the Case for SHARP -- MYTH: Good Leaders Focus on Eliminating or Overcoming Their Weaknesses -- MYTH: People Are Happiest and Most Productive When They Eliminate Stress from Their Lives -- MYTH: Peak Experiences Are Necessarily Rare, a Product of Special and Extraordinary Events -- MYTH: The Most Important Tools for a Good Leader Are Power and Control -- MYTH: The Key to Fulfillment Lies in Seeking and Finding the Meaning of Life -- MYTH: Achievement and Success Lead to Happiness and Fulfillment -- Becoming SHARP -- Part II: What 10X Leaders Do -- Chapter 4: Strengths: Making the Most of Your Gifts -- The Tragedy of the Damage Control Mind‐Set -- Passion Strengths and Performance Strengths: Discovering Your Peak Potential Zone -- The Mastery Experience: Building Self‐Confidence -- Leading with Strengths -- Connecting the Dots: A Note on Courage, Patience, and Serendipity -- Chapter 5: Health: Injecting Energy into Life and Work -- Managing Energy, Not Time -- On Depletion and Recovery: The Energy Creation Zone -- In the ECZ: Lessons from the Blue Zones -- The Replenishing Role of Positive Emotions -- Managing Team Energy: Setting the Tone, Setting the Pace -- Chapter 6: Absorption: Revealing the Extraordinary in the Ordinary through Mindful Engagement -- The Importance of Mindfulness -- Flow 101.…”
    Libro electrónico
  4. 1444
    Tabla de Contenidos: “…A study on risk early warning of crops caused by floods in Northeast China based on vulnerabilityScenario-based risk assessment and zonation of paddy caused by flood in Huai River sub-basin of China; Application of capacity spectrum for Wenchuan earthquake damage risk analysis: The Dujiangyan study; Design and implementation of crop risk assessment and zoning system; Predicting agricultural drought disaster loss based on SPI and ANN in Shandong, China; Applications of health risk classification method in pre-evaluations of occupational disease hazards in construction projects in China…”
    Libro electrónico
  5. 1445
    por Lepofsky, Ron. author
    Publicado 2014
    Tabla de Contenidos: “…Understanding the Testing ProcessWeb Application Audits; Vulnerability Assessment; Fully Automated Testing; Manual Testing; Combining Automated and Manual Testing; Penetration Testing; Postremediation Testing; Important Report Deliverables for All Testing Reports; Summary; Chapter 3: Web Application Vulnerabilities and the Damage They Can Cause; Lack of Sufficient Authentication; Weak Password Controls; Passwords Submitted Without Encryption; Username Harvesting; Weak Session Management; Weak SSL Ciphers Support; Information Submitted Using the GET Method…”
    Libro electrónico
  6. 1446
    por Landy, Gene K.
    Publicado 2008
    Tabla de Contenidos: “…Absence of Defenses; Registering Your Copyright; How Copyright Registration Works; Advantages of Copyright Registration; Statutory Damages under the Copyright Act; Getting a Good Shot at Attorneys' Fees; Filing for Timely Copyright Registration; Presumption of Validity of Your Copyright; Making Copyright Registration a Regular Practice; Recording Assignments and Exclusive Licenses; Criminal Copyright Violations; More on Copyright Law; Conclusion; Chapter 3: Copyrights on the Internet, for Software Protection and Around the World; In this Chapter…”
    Libro electrónico
  7. 1447
    por Kelly, Bob
    Publicado 2008
    Tabla de Contenidos: “…Chapter 11 Securing the WorkstationBeginning with Basic Security; Applying the Castle Defense System; Summary; Chapter 12 Protecting User Data; Protecting User Profiles; Providing User Data Protection; Using the Encrypting File System; Running BitLocker Full Drive Encryption; Summary; Chapter 13 Recovering Damaged Systems and Lost Data; Recovering Systems; Recovering Data; Summary; Appendix What's on the CD-ROM; System Requirements; Using the CD; What's on the CD; Troubleshooting; Index…”
    Libro electrónico
  8. 1448
    Publicado 2014
    Tabla de Contenidos: “…CHAPTER 4 Income or Loss from Business OperationsBusiness Income; Payment Methods; Income for Service Businesses; 1099 Income; Advances and Prepayments; Income from the Sale of Goods; Cost of Goods Sold; Gross Profits; Other Income for Direct Sellers; Income from Farming; Farm Income Averaging; Investment-Type Income; Interest Income; Dividends; Rents; Cancellation of Debt; Damages and Other Recoveries; Miscellaneous Business Income; Special Income Items for S Corporations; Special Income Items for C Corporations; State Income Taxes on Business Income; Net Operating Losses; Calculating NOLs…”
    Libro electrónico
  9. 1449
    por Weinzimmer, Laurence G.
    Publicado 2012
    Tabla de Contenidos: “…; The Consequences of Old-School Management; Why Good People Become Old-School Leaders; Why Good People Tolerate Old-School Managers; Ending Old-School Management and Repairing the Damage; Recognize; Repurpose; Reform; Define; If the Military Can Do It, So Can You; SIX: When Utopia Becomes Dystopia; Why We Want Utopia-And Why We Shouldn't; Constructive Conflict Is Missing; Bosses Make Bad Friends; Trust Erodes; Initiative Suffers; The Bottom Line Sinks…”
    Libro electrónico
  10. 1450
    por Winterfeld, Steve
    Publicado 2013
    Tabla de Contenidos: “…Measures of Effectiveness (MOE)Battle Damage Assessment (BDA); Close Air Support (CAS); Counterinsurgency (COIN); Summary; References; 4 Tools and Techniques; Logical Weapons; Reconnaissance Tools; Scanning Tools; Access and Escalation Tools; Exfiltration Tools; Sustainment Tools; Assault Tools; Obfuscation Tools; Physical Weapons; How the Logical and Physical Realms are Connected; Logical Systems Run on Physical Hardware; Logical Attacks Can Have Physical Effects; Infrastructure Concerns; What is SCADA?…”
    Libro electrónico
  11. 1451
    por Singer, Eric
    Publicado 2012
    Tabla de Contenidos: “…Trade the Congressional Effect; Contents; Acknowledgments; Introduction; Our Damaged Economy; Congress's Role in Wealth Destruction; Summary; Notes; Chapter 1 What Is the Congressional Effect?…”
    Libro electrónico
  12. 1452
    Publicado 2012
    Tabla de Contenidos: “…6Predicting forces and damage in drilling of polymer composites: soft computing techniques6.1 Drilling of polymer composites; 6.2 Soft computing techniques; 6.3 References; 7Minimising burr size in drilling: integrating response surface methodology with particle swarm optimisation; 7.1 Introduction; 7.2 Response surface methodology; 7.3 Particle swarm optimisation; 7.4 Experimental details; 7.5 Results and discussion; 7.6 Conclusions; 7.7 References; 8Single-point incremental forming of polymers; 8.1 Introduction; 8.2 Theoretical framework; 8.3 Experimental background…”
    Libro electrónico
  13. 1453
    Publicado 2014
    Tabla de Contenidos: “…Chapter 12: Energy Issues in Nanoindentation; Chapter 13: Dynamic Contact Damage in Glass; Chapter 14: Does the Speed of Dynamic Contact Matter?…”
    Libro electrónico
  14. 1454
    Publicado 2012
    Tabla de Contenidos: “…Full Text; Professional and Consultant Service Costs; Security; Liquidated Damages; Order of Precedence; Price Evaluation Preferences; Small Business Subcontracting Plan; Clause Inclusion and Flowdown; Recordkeeping; Davis-Bacon Act (Prevailing Wages); General FAR Requirements; Who Is Allowed to Work; Site of the Work…”
    Libro electrónico
  15. 1455
    por Hallam, Andrew
    Publicado 2011
    Tabla de Contenidos: “…Internet Madness and the Damage It CausedTaking Advantage of Fear and Greed; Opportunities after Chaos; Rule 5: Build Mountains of Money with a Responsible Portfolio; What Are Bonds?…”
    Libro electrónico
  16. 1456
    por Devine, Tom
    Publicado 2011
    Tabla de Contenidos: “…; Facing Conflicting Values and Goals; Whistleblowers at Their Best; Reality Check for the Aspiring Whistleblower; Shooting the Messenger; The Personal Price; CHAPTER 2 The Red Flags; Targeting Dissenters: Tactics of Retaliation; Spotlight the Whistleblower, Not the Wrongdoing; Build a Damaging Record against the Whistleblower; Threaten Them; Isolate Them; Set Them Up for Failure…”
    Libro electrónico
  17. 1457
    por Roberts, Dan 1963-
    Publicado 2011
    Tabla de Contenidos: “…; Conclusion; 5 Negotiating: Getting What You Want without Damaging the Relationship; Position versus Interest Negotiations; Three Key Factors; Three-Step Process; Applying the Key Factors to the Second Step: Information Exchange; The Final Step: Now Comes the Bargaining…”
    Libro electrónico
  18. 1458
    Publicado 2014
    Tabla de Contenidos: “…Judicial Interpretation of the Criteria; a) Indirect International Jurisdiction; b) Natural Justice; c) Ordre Public; d) Reciprocity; e) Punitive Damages; V. Conclusions; Stefania BARIATTI: Jurisdiction, Choice of Law and the Recognition of Foreign Judgments in Recent EU Legislation; I. …”
    Libro electrónico
  19. 1459
    Publicado 2022
    Tabla de Contenidos: “…Reactive Oxygen Species, Oxidative Damage and Their Production, Detection in Common Bean (Phaseolus vulgaris L.) under Water Stress Conditions By Asmat Ara, Mahroofa Jan, Parvaze A. …”
    Libro electrónico
  20. 1460
    Publicado 2013
    Tabla de Contenidos: “…Summary -- Introduction -- 1.1 Protein aggregation and amyloidoses -- 1.1.1 Mechanisms of amyloid fibril formation -- 1.1.2 Oligomer structural polymorphism: fibrillar and prefibrillar oligomers -- 1.1.3 Oligomer toxicity: common mechanism of pathogenesis -- 1.1.4 Amyloid formation is an inherent property of polypeptide chains: functional amyloid and disease unreleated amyloid -- 1.2 HypF-N: model protein of amyloid aggregation unrelated to disease -- 1.2.1 Function, structure and aggregation of HypF-N -- 1.2.2 HypF-N protofibrils interact with cell membranes originating a cytotoxic cascade -- 1.2.3 A causative link between the structure of HypF-N oligomers and their ability to cause cellular dysfunction -- 1.3 Alzheimer's disease -- 1.3.1 The Alzheimer phenotype -- 1.3.2 The elaborate processing of APP -- 1.3.3 The genetics of Alzheimer's disease -- 1.3.4 Peripheral cells as a tool to identify and test hypotheses on AD pathophysiology -- 1.3.5 Adult neurogenesis and stem cell technology for AD -- 1.4 Cholesterol and gangliosides in the central nervous system (CNS) -- 1.4.1 Brain cholesterol metabolism -- 1.4.2 Ganglioside metabolism -- 1.4.3 Lipid rafts -- 1.4.4 Role of cholesterol in AD -- 1.4.5 Role of gangliosides in AD -- 1.5 Aim of the study -- Materials & Methods -- 2.1 Materials -- 2.1.1 Chemicals -- 2.1.2 Fluorescent probes -- 2.1.3 Peptides and aggregation protocols -- 2.2 Cell cultures -- 2.3 Methods -- 2.3.1 Separation processes -- 2.3.2 Differentiation of human mesenchymal stromal cells -- 2.3.3 Modulation of membrane cholesterol levels -- 2.3.4 Modulation of membrane GM1 levels -- 2.3.5 Cholesterol content measurements -- 2.3.6 GM1 content measurements -- 2.3.7 Cell exposure to peptide aggregates -- 2.3.8 Analysis of aggregate interaction with the cells -- 2.3.9 Analysis of aggregate interaction with GM1 -- 2.3.10 Analysis of aggregate internalisation -- 2.3.11 Analysis of membrane permeability -- 2.3.12 Analysis of cytosolic Ca2+ dyshomeostasis -- 2.3.13 Evaluation of ROS production -- 2.3.14 Analysis of lipid peroxidation -- 2.3.15 Cytotoxicity assay and cell death analysis: apoptotic and necrotic markers -- 2.3.16 Steady-state fluorescence anisotropy -- 2.3.17 Atomic force microscopy (AFM) -- 2.3.18 Measurements of the fluorescence intensities -- 2.3.19 Statistical analysis -- Results -- 3.1 Results I -- 3.1.1 A protective role for lipid raft cholesterol against amyloidinduced membrane damage in human neuroblastoma cells -- 3.1.2 Aß42 oligomer binding to the cell surface and its cytotoxic effect are modulated by membrane cholesterol content -- 3.1.3 Aß42 oligomers colocalize with lipid rafts -- 3.1.4 Isolation and characterization of DRMs -- 3.1.5 Effects of ADDLs on lipid raft structural order -- 3.1.6 AFM imaging of supported DRMs purified from cells exposed to ADDLs -- 3.2 Results II -- 3.2.1 Lipid rafts mediate amyloid-induced calcium dyshomeostasis and oxidative stress in Alzheimer's disease -- 3.2.2 Lipid rafts are primary interaction sites for Aß42 oligomers at the plasma membrane -- 3.2.3 Cholesterol and GM1 mediate Aß42 accumulation at the plasma membrane -- 3.2.4 Cholesterol and GM1 mediate Ca2+ dyshomeostasis and extensive membrane permeabilization induced by Aß42 oligomers -- 3.2.5 GM1 modulates lipid peroxidation and cytotoxicity induced by Aß42 oligomers -- 3.2.6 GM1 mediates Aß42-induced Ca2+ dyshomeostasis, lipid peroxidation and cytotoxicity in rat cortical neurons -- 3.3 Results III -- 3.3.1 Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers -- 3.3.2 Membrane cholesterol content modulates oligomer cytotoxicity -- 3.3.3 Membrane cholesterol modulates oligomer-induced alteration of intracellular Ca2+ homeostasis and ROS levels -- 3.3.4 Cholesterol levels modulate membrane permeability to the oligomers -- 3.3.5 Membrane GM1 affects the cytotoxic and permeabilizing effects of HypF-N oligomers -- 3.3.6 GM1, rather than cholesterol, plays a dominant role in oligomer cytotoxicity and membrane permeability -- 3.4 Results IV -- 3.4.1 Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aß42 aggregate toxicity -- 3.4.2 Neuronal differentiation of hMSCs results in reduced levels of membrane GM1 -- 3.4.3 Neuronal differentiation of hMSCs reduces the interaction of Aß42 oligomers with the cell surface -- 3.4.4 Neuronal differentiation of hMSCs reduces Aß42 oligomerinduced intracellular Ca2+ dyshomeostasis and oxidative stress -- 3.4.5 Neuronal differentiation of hMSCs increases cell resistance to Aß42 aggregates Discussion -- 4.1 A protective role for lipid raft cholesterol against amyloid-induced membrane damage in human neuroblastoma cells -- 4.2 Lipid rafts mediate amyloid-induced calcium dyshomeostasis and membrane permeabilization in Alzheimer's fibroblasts -- 4.3 Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers -- 4.4 Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aß42 aggregate toxicity -- 4.5 Concluding remarks -- Abbreviations -- References…”
    Libro electrónico