Tabla de Contenidos: “…Dinkova-Kostova -- Nutritional redox homeostasis and cellular stress response: differential role of homocysteine and acetylcarnitine / Vittorio Calabrese ... …”

“…Metabolic engineering seeks to enhance cellular biosynthetic productivity of target metabolites via controlling and redesigning metabolic pathways using multi-omics analysis, genome-scale modeling, metabolic flux control, and reconstruction of novel pathways. …”

“…Disruption of an organ parenchymal cells and of its normal structural scaffold during tissue fibrogenesis appears to induce loss of cell polarity, promoting uncontrolled cell proliferation that may eventually lead to cancer development. Many cellular and molecular abnormalities including aberrant expression of microRNAs, genetic and epigenetic alterations, evasion or delayed apoptosis, unregulated intracellular signal pathways, and dysregulation or defective intercellular communications have been proposed to explain this link between fibrogenesis and carcinogenesis. …”

“…Griffin, vice president, organizational learning and chief teaching officer, U.S. Cellular ""Only from the Center for Creative Leadership could we expect to see such a rich, authoritative, and actiona…”

“…In this book, we present a compilation of original research articles as well as review articles that are focused on improving our understanding of the molecular and cellular mechanisms by which cancer cells adapt to their microenvironment. …”

“…They control virtually every cellular process and are essential for animal development, cell differentiation, and homeostasis. …”

“…They share common molecular and cellular characteristics, including protein misfolding, mitochondrial dysfunction, glutamate toxicity, dysregulation of calcium homeostasis, oxidative stress, inflammation, and ageing, which contribute to neuronal death. …”

“…You'll find out how to use Python to automate lab calculations, search for gene promoter sequences, rotate a molecular bond, build a cellular toggle switch, model animal coat pattern formation, grow a virtual plant, simulate a flu epidemic, or evolve populations. …”

Tabla de Contenidos: “…The Hazards of Regeneration: From Morgan’s Legacy to Evo-Devo -- Studying Regeneration in Ascidians: An Historical Overview -- Studying Protista WBR and Repair using Physarum polycephalum -- Studying Porifera WBR using the Calcerous Sponges Leucosolenia -- Studying Ctenophora WBR using Mnemiopsis leidyi -- Studying Placozoa WBR in the Simplest Metazoan Animal, Trichoplax adhaerens -- Collecting and Culturing Kamptozoans for Regenerative Studies -- Collecting and Culturing Bryozoans for Regenerative Studies -- Studying Annelida Regeneration in a Novel Model Organism: The Freshwater Aeolosoma viride -- Studying Annelida Body Regeneration under Environmental Stress in Diopatra neapolitana -- Studying Annelida Regeneration using Platynereis dumerilii -- Collecting and Culturing Lineus sanguineus to Study Nemertea WBR -- Studying Xenacoelomorpha WBR using Isodiametra pulchra -- Studying Echinodermata Arm Explant Regeneration using Echinaster sepositus -- Studying Hemichordata WBR using Ptychodera flava -- Studying Tunicata WBR using Botrylloides anceps -- In Situ Hybridization to Identify Stem Cells in the Freshwater Sponge Ephydatia fluviatilis -- Isolation and Maintenance of In Vitro Cell Cultures from the Ctenophore Mnemiopsis leidyi -- Analysis of Spatial Gene Expression at the Cellular Level in Stony Corals -- Studying Stem Cell Biology in Intact and Whole-Body Regenerating Hydra by Flow Cytometry -- Non-Invasive Intra-Vascular Micro-Transfusion in Colonial Tunicates -- Gene Manipulation in Hydractinia -- Manipulation of Gene Activity in the Regenerative Model Sea Anemone, Nematostella vectensis -- Monitoring Telomere Maintenance during Regeneration of Annelids -- Analysis of DNA Double Stranded Breaks using the COMET Assay in Planarians -- Random Integration Transgenesis in a Free-Living Regenerative Flatworm Macrostomum lignano -- RNAi Screening to Assess Tissue Regeneration in Planarians -- Monitoring Chromatin Regulation in Planarians using Chromatin Immunoprecipitation followed by Sequencing (ChIP-seq) -- Assessing Chromatin Accessibility during WBR in Acoels -- Single Cell Transcriptomic Analysis in the Regenerating Cnidarian Nematostella vectensis -- Characterization of Soluble Cell-Free Coelomic Fluid Proteome from the Starfish Marthasterias glacialis -- Using RNA-Sequencing for Transcriptome Profiling of Botrylloides sp. …”

“…Over the last few years, new findings on TRP channels have confirmed their exceptional function as cellular sensors and effectors. This Special Book features a collection of 8 reviews and 7 original articles published in “Cells” summarizing the current state-of-the-art on TRP channel research, with a main focus on TRP channel activation, their physiological and pathophysiological function, and their roles as pharmacological targets for future therapeutic options…”

“…The articles include in this book highlight new developments in therapeutic approaches for wound repair including the use of nanomedicine and biomaterials to deliver cells and/or drugs to promote healing. Cellular responses that underpin angiogenesis, inflammation, proliferation and remodeling, as well as advances in cytoskeletal interactions in keratinocytes and fibroblast cell functions. …”

“…Ion channels are membrane proteins that selectively allow ions to flow down their electrochemical gradient across the cellular membrane. They localize in both plasma and intracellular membranes and regulate a variety of functions such as neuronal excitability, heartbeat, muscle contraction and hormones release. …”

“…With integrated biosensors, these devices allow the development and design of micro- and nanoparticles to be studied in detail, modelling human physiology, investigating the molecular and cellular mechanisms underlying disease formation and progression, and gaining insights into the performance and long-term effects of responsive drug delivery nanocarriers. …”

Tabla de Contenidos: “…Note continued: ch. 13 Transportation -- Transportation and Transports -- Transportation Challenges -- Roadways -- Mass Transit -- Rail -- Challenges for Transportation Operators and Users -- IoT Use Cases for Transportation -- Connected Cars -- Connected Fleets -- Infrastructure and Mass Transit -- An IoT Architecture for Transportation -- IoT Technologies for Roadways -- Bluetooth -- Cellular/LTE -- An Introduction to DSRC and WAVE -- DSRC/WAVE Protocol and Architecture -- Connected Roadways Network Architecture -- Connected Fleet Architecture -- Connected Roadways Security -- Extending the Roadways IoT Architecture to Bus Mass Transit -- Mass Transit Security -- Extending Bus IoT Architecture to Railways -- Connected Stations -- Connected Train Security -- Summary -- References -- ch. 14 Mining -- Mining Today and Its Challenges -- Scale -- Safety -- Environment -- Security -- Volatile Markets -- Challenges for IoT in Modern Mining -- The OT Roles in Mining -- Connectivity -- An IoT Strategy for Mining -- Improved Safety and Location Services -- Driver Safety -- Weather and Lightning -- Slope Monitoring -- Location Services -- Hazardous Gas Detection -- Environmental Monitoring -- Improved Efficiencies -- Improved Collaboration -- IoT Security for Mining -- An Architecture for IoT in Mining -- IEEE 802.11 as the IoT Access Layer -- 802.11 Outdoor Wireless Mesh -- 802.11 Wireless Mesh Backhaul Considerations -- Wi-Fi Clients -- Antenna Considerations for Wireless Mesh -- 4G/LTE -- Wireless in Underground Mining -- Industrial Wireless -- Isolated vs. …”

Tabla de Contenidos:

Tabla de Contenidos: “…19.3 Fundamentals of Atomic Switches -- 19.4 Various Atomic Switches -- 19.5 Perspectives -- References -- Chapter 20: ITRS Assessment and Benchmarking of Emerging Logic Devices -- 20.1 Introduction -- 20.2 Overview of the ITRS Roadmap for Emerging Research Logic Devices -- 20.3 Recent Results for Selected Emerging Devices -- 20.4 Perspective -- 20.5 Summary -- Acknowledgments -- References -- Part Four: Concepts for Emerging Architectures -- Chapter 21: Nanomagnet Logic: A Magnetic Implementation of Quantum-dot Cellular Automata -- 21.1 Introduction -- 21.2 Technology Background -- 21.3 NML Circuit Design Based on Conventional, Boolean Logic Gates -- 21.4 Alternative Circuit Design Techniques and Architectures -- 21.5 Retrospective, Future Challenges, and Future Research Directions -- References -- Chapter 22: Explorations in Morphic Architectures -- 22.1 Introduction -- 22.2 Neuromorphic Architectures -- 22.3 Cellular Automata Architectures -- 22.4 Taxonomy of Computational Ability of Architectures -- 22.5 Summary -- References -- Chapter 23: Design Considerations for a Computational Architecture of Human Cognition -- 23.1 Introduction -- 23.2 Features of Biological Computation -- 23.3 Evolution of Behavior as a Basis for Cognitive Architecture Design -- 23.4 Considerations for a Cognitive Architecture -- 23.5 Emergent Cognition -- 23.6 Perspectives -- References -- Chapter 24: Alternative Architectures for NonBoolean Information Processing Systems -- 24.1 Introduction -- 24.2 Hierarchical Associative Memory Models -- 24.3 N-Tree Model -- 24.4 Summary and Conclusion -- Acknowledgments -- References -- Chapter 25: Storage Class Memory -- 25.1 Introduction -- 25.2 Traditional Storage: HDD and Flash Solid-state Drives -- 25.3 What is Storage Class Memory? …”

Tabla de Contenidos: “…OFDM Baseband Receiver Design for Wireless Communications; Contents; Preface; About the Authors; Acknowledgements; 1 Introduction; 1.1 Wireless Communication Systems; 1.1.1 Digital Broadcasting Systems; 1.1.2 Mobile Cellular Systems; 1.1.3 Wireless Network Systems; Bibliography; 2 Digital Modulation; 2.1 Single-Carrier Modulation; 2.1.1 Power Spectral Densities of Modulation Signals; 2.1.2 PSK, QAM and ASK; 2.1.3 CPFSK and MSK; 2.1.4 Pulse Shaping and Windowing; 2.2 Multi-Carrier Modulation; 2.2.1 Orthogonal Frequency-Division Multiplexing; 2.2.2 OFDM-Related Issues…”

Tabla de Contenidos: “…The Importance of Planning -- Resolving Overloads -- Automated Planning -- Planning Example -- Characteristics of a Good Production Plan -- Managing Inventory Targets and Constraints -- Summary -- 22 Workforce Engagement -- Selling the Idea -- Designing the New Process -- Executing the New Process -- 23 Changeover Reduction - SMED -- SMED and Its Origins -- SMED Concepts -- Process Industry Changeovers -- Automotive Fluids Packaging -- Diaper Manufacturing -- SMED Beyond Product Changes -- A Non-Manufacturing Example -- SMED Applied to Blue Lakes Packaging -- Summary -- 24 Production Stability -- Total Productive Maintenance -- TPM Relevance in Process Industries -- TPM Saves Money -- Overall Equipment Effectiveness (OEE) -- Availability -- Performance -- Quality -- Calculation of OEE -- VSM Data Boxes: OEE -- Non-Standard OEE Metrics -- Summary -- 25 Cellular Manufacturing -- Typical Process Plant Equipment Configurations -- Cellular Manufacturing Applied to Process Lines -- Synthetic Sheet Manufacturing Example -- Virtual Cell Implementation in a Synthetic Rubber Production Facility -- Would Cellular Flow Apply to the Salad Dressing Operation? …”

Tabla de Contenidos: “…Lewisite -- EVIDENCE OF LONG-TERM HEALTH EFFECTS OF MUSTARD AGENTS -- Animal Studies and Cellular Bioassays -- Human Studies -- Occupational Exposure -- Battlefield Exposure -- Medical Therapeutic Exposure -- Experimental Exposure -- EVIDENCE OF LONG-TERM HEALTH EFFECTS OF LEWISITE -- Animal Studies and Cellular Bioassays -- Human Studies -- Occupational Exposure -- Battlefield Exposure -- Medical Therapeutic Exposure -- Experimental Exposure -- SUMMARY -- Gaps in the Literature -- Conclusions -- REFERENCES -- 10 Other Physiological Effects of Mustard Agents and Lewisite -- EFFECTS ON THE IMMUNE SYSTEM -- Anatomy and Physiology -- Animal Studies -- Human Studies -- Conclusions -- EFFECTS ON SYSTEMS OTHER THAN THE IMMUNE SYSTEM -- Gastrointestinal Effects -- Hematological Effects -- Neurological Effects -- Conclusions -- REPRODUCTIVE RISKS -- Sulfur Mustards -- Animal Studies -- Human Studies -- Summary and Conclusions -- Lewisite -- Introduction -- Animal Studies -- Human Studies -- Summary and Conclusions -- REFERENCES -- 11 Relationship of Mustard Agent and Lewisite Exposure to Psychological Dysfunction -- HISTORICAL DEVELOPMENT OF THE CONCEPT OF PTSD -- CURRENT RESEARCH IN PTSD -- EVIDENCE FROM STUDIES OF MILITARY PERSONNEL AND VETERANS -- Chemical and Biological Warfare Environments -- Studies of PTSD in Veteran Populations -- EVIDENCE FROM STUDIES OF THE PSYCHOLOGICAL EFFECTS OF ENVIRONMENTAL CONTAMINATIONS -- CONCLUSIONS -- REFERENCES -- 12 Summary of Findings and Recommendations -- GENERAL CONCLUSIONS -- CONCLUSIONS REGARDING THE CAUSAL RELATIONSHIPS OF EXPOSURE TO THE DEVELOPMENT OF SPECIFIC DISEASES -- GAPS IN THE LITERATURE REGARDING MUSTARD AGENTS AND LEWISITE -- Human Studies -- Animal Studies -- RECOMMENDATIONS -- Bibliography -- PUBLISHED LITERATURE -- MILITARY REPORTS UNITED STATES -- U.S. …”

Tabla de Contenidos: “…Predictive Location Tracking in Cellular and in Ad Hoc Wireless Networks -- 9. An Efficient Air Index Scheme for Spatial Data Dissemination in Mobile Computing Environments -- 10. …”