“…This book is prepared in two volumes to introduce recent advances in different areas of biomedical engineering such as biomaterials, cellular engineering, biomedical devices, nanotechnology, and biomechanics. …”

“…This eBook provides a comprehensive update on TGF-β signalling pathways and introduces a range of cellular and molecular mechanisms involved in renal fibrosis both upstream and downstream of TGF-β. …”

“…Detailed multiscale models were used to study the effect of structural remodeling induced at the cellular and tissue levels. Simulated electrograms were used to train a machine-learning algorithm to characterize the substrate. …”

“…Therefore, investigation and modulation of protein interactions are of significance as it not only reveals the mechanism governing cellular activity, but also leads to potential agents for the treatment of various diseases. …”

“…As regulators of protein function, protein kinases are involved in the control of cellular functions via intricate signalling pathways, allowing for fine tuning of physiological functions. …”

“…Areas covered include: general biochemistry, patho-biochemistry, evolutionary biology, structural biology, molecular and cellular biology, molecular medicine, cancer research, virology, immunology, plant molecular biology and biochemistry, and experimental methodologies…”

“…Computational biology approaches for image-based analysis of multicellular spheroids, feature selection using entropy and cellular cryo-electron tomography structural pattern mining are covered. …”

“…It also has abundant information on recent advances and cutting-edge knowledge in intracellular molecular cross-talking of retinoblastoma protein with various cellular viral-like proteins…”

“…By reviewing emerging cellular, pharmacological, rehabilitative, as well as surgical approaches, this book seeks to highlight promising therapeutic strategies for the repair and regeneration of motor circuitry. …”

“…As regulators of protein function, protein kinases are involved in the control of cellular functions via intricate signalling pathways, allowing for fine tuning of physiological functions. …”

“…Brain function is under metabolic control, which in turn determines the equilibrium of homeostatic systems that affect neuronal and glial networks on the molecular, cellular, and systems levels. The collection of articles ranges from molecules and mechanisms involved in regulating homeostasis and neuronal excitability to therapeutic mechanisms tailored to restore homeostatic function. …”

“…Interactions between nucleic acids and proteins are essential requirements for the viability of cellular life because they are indispensable for many basic biological processes. …”

“…A regulated diet with all necessary constituents consumed in an appropriate way maintains cell homeostasis and keeps the body under a physiological state essential for cellular demands. This book deals with problems of mineral deficiencies, which can arise due to decreased consumption of certain foods, malabsorption syndrome, bleeding disorders, a diet with insufficient nutritional content, and so on…”

“…Underscoring its importance is the wide array of neural and cellular processes that have evolved to govern when and how it occurs, its duration, sequence of phases, and the influence it exerts on numerous other brain functions. …”

“…One of the causes of most age-related diseases is an imbalance in the oxidation-reduction reactions, with the accumulation of reactive species, which are major contributors to cellular senescence. The book contributes to the knowledge connected to the prevention or treatment of these pathological conditions. …”

“…Polyamines are ubiquitous polycations essential for all cellular life. The most common polyamines in eukaryotes, spermine, spermidine, and putrescine, exist in millimolar intracellular concentrations that are tightly regulated through biosynthesis, catabolism, and transport. …”

“…Horticulture Research is an online only, open-access international journal devoted to publish original research results and reviews on, but not limited to, genetics, genomics and breeding, biotechnology, biochemistry, physiology, cellular and molecular biology, evolution, and environmental biology of horticultural plants. …”

Tabla de Contenidos: “…Cover -- Half Title -- Title Page -- Copyright Page -- Table of Contents -- Preface to the Second Edition -- Author -- Part I Introduction to Cellular and Molecular Biology -- 1 The Cellular System and the Code of Life -- 1.1 The Cellular Challenge -- 1.2 How Cells Meet the Challenge -- 1.3 Molecules in Cells -- 1.4 Intracellular Structures Or Spaces -- 1.4.1 Nucleus -- 1.4.2 Cell Membrane -- 1.4.3 Cytoplasm -- 1.4.4 Endosome, Lysosome, and Peroxisome -- 1.4.5 Ribosome -- 1.4.6 Endoplasmic Reticulum -- 1.4.7 Golgi Apparatus -- 1.4.8 Cytoskeleton -- 1.4.9 Mitochondrion -- 1.4.10 Chloroplast -- 1.5 The Cell as a System -- 1.5.1 The Cellular System -- 1.5.2 Systems Biology of the Cell -- 1.5.3 How to Study the Cellular System -- References -- 2 DNA Sequence: The Genome Base -- 2.1 The DNA Double Helix and Base Sequence -- 2.2 How DNA Molecules Replicate and Maintain Fidelity -- 2.3 How the Genetic Information Stored in DNA Is Transferred to Protein -- 2.4 The Genomic Landscape -- 2.4.1 The Minimal Genome -- 2.4.2 Genome Sizes -- 2.4.3 Protein-Coding Regions of the Genome -- 2.4.4 Non-Coding Genomic Elements -- 2.5 DNA Packaging, Sequence Access, and DNA-Protein Interactions -- 2.5.1 DNA Packaging -- 2.5.2 Sequence Access -- 2.5.3 DNA-Protein Interactions -- 2.6 DNA Sequence Mutation and Polymorphism -- 2.7 Genome Evolution -- 2.8 Epigenome and DNA Methylation -- 2.9 Genome Sequencing and Disease Risk -- 2.9.1 Mendelian (Single-Gene) Diseases -- 2.9.2 Complex Diseases That Involve Multiple Genes -- 2.9.3 Diseases Caused By Genome Instability -- 2.9.4 Epigenomic/Epigenetic Diseases -- References -- 3 RNA: The Transcribed Sequence -- 3.1 RNA as the Messenger -- 3.2 The Molecular Structure of RNA -- 3.3 Generation, Processing, and Turnover of RNA as a Messenger -- 3.3.1 DNA Template -- 3.3.2 Transcription of Prokaryotic Genes…”

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