“…While at this time CKD progression is not treated with high efficacy, new biomarkers of kidney fibrosis have become available in recent years and new treatments for kidney fibrosis and cell loss could become soon available. In addition recent progress in our understanding of CKD pathophysiology together with the development of novel therapeutic agents has led to a renewed attention on the treatment of CKD-associated metabolic complications which are now are amenable to therapeutic interventions. …”

“…Non-Invasive Prenatal Testing (NIPT) measures the underlying genetic pathology of trisomies directly by analyzing fetal genetic material in the maternal circulation (cell-free fetal DNA, cffDNA). Several commercial testing strategies are available using different sequencing techniques for screening of trisomy 21, 18 and 13. …”

“…During pregnancy and birth, there is a danger that these women produce antibodies against fetal blood cells (alloimmunization), if the fetus is RhD-positive. …”

“…Hydrogen could contribute to China's energy system decarbonisation strategy, such as through the use as a fuel and feedstock in industrial processes; in fuel cell electric transport, and for the production of synthetic hydrocarbon fuels for shipping and aviation. …”

“…Vitamin C has a plethora of physiologic effects, primarily due to its activity as a cofactor for a growing group of biosynthetic and regulatory enzymes, with the potential to regulate thousands of genes and cell signaling pathways. Small interventional studies have indicated that administration of gram doses of vitamin C to patients with pneumonia and sepsis improves organ function and potentially decreases mortality, although this remains to be confirmed in larger trials. …”

Accés lliure a continguts extres en anglès amb la compra individual del llibre

“…Experimental studies suggest that the development of kidneys in fetuses and the function of insulin-producing cells may be adversely affected by Cd and that metformin, an anti-diabetic drug, is ineffective in Cd-intoxicated Wistar rats…”

“…Some metals have become strategic and critical because they are used in many technological applications such as flat panel TVs (indium), solar panel cells (indium), lithium-ion batteries for electric vehicles (lithium, cobalt), magnets (rare earth elements, such as neodymium and dysprosium), scintillators (rare earths), and aviation and medical applications (titanium); their availabilities remain limited. …”

“…Human T-cell leukemia viruses 1 and 2 (HTLV-1 and HTLV-2) have similar genomic structure but differ in pathogenicity. …”

“…Sylvester describe g-Tocotrienol, a natural isoform within the vitamin E family of compounds, which displays potent antiproliferative, apoptotic and reversal of epithelial-to-mesenchymal-transition activity against breast cancer, employing treatment doses that have little or no effect on normal cell viability. The chapter by Milka Mileva and Angel S. …”

“…Acquired immunodeficiency syndrome (AIDS) is an advanced form of HIV infection in which the patient has developed opportunistic infections or certain types of cancer and/or the CD4+ T cell count has dropped below 200/μL. More than 40 million persons around the world are infected with HIV, with approximately 14,000 new infections every day. …”

“… « Nombreux sont les acteur.ice.s de la médiation numérique qui se retrouveront dans la vingtaine de propositions qui concluent cette étude, et constituent un éclairage d'actualité utile à toutes celles et ceux qui s'attachent à ce que la transformation numérique n'aggrave encore plus les inégalités mais soit, à l’inverse, synonyme d'inclusion et de pouvoir d'agir de chacun.e. » Michel Briand (extrait de la préface)…”

“…Marquent-ils la fin d'un cycle ouvert par la séquence 1936-1946 et dont les bornes ne coïncideraient pas avec celles des Trente Glorieuses ? Sont-ils annonciateurs d'une séquence nouvelle et, dans cette hypothèse, laquelle ? …”

“…La formalisation mathématique de ces notions a permis d'abord le grand développement de la théorie des treillis, puis celui de structures ordonnées plus générales, notamment celles relevant des mathématiques discrètes. Les buts principaux de cet ouvrage qui comble un vide sont donc de: - donner les concepts et résultats fondamentaux sur les ensembles ordonnés finis, - présenter leurs usages dans des domaines variés (de la RO ou l’IA à la micro-économie), - signaler un certain nombre de résultats et de recherches en cours. …”

“…De la reconstruction d’après-guerre aux mobilisations des années 1968, des relations complexes de la France avec ses anciennes colonies à celles qu’elle entretient avec les dictatures militaires d’Europe septentrionale et d’Amérique du Sud, cet ouvrage collectif retrace le demi-siècle d’un « campus monde » unique en son genre et offre une synthèse inédite d’histoire sociale et transnationale sur une institution représentant pour les sciences sociales un fascinant observatoire de la mondialisation…”

“…The dual role of nickel as both an essential nutrient and as a toxin has prompted efforts to understand the molecular mechanisms of nickel toxicology and to uncover the means by which cells select nickel from among a pool of different and more readily available metal ions and thus regulate the intracellular chemistry of nickel. …”

“…There is a detailed look at clean fuels and advanced technologies such as "clean diesel", CNG, hybrid-electric and fuel cells. Case studies are made of six cities and of the steps each might take to encourage more sustainable transport systems…”

“…Ce rapport examine les pratiques de gestion des exploitations propices à la croissance verte, aussi bien les innovations menées par les agriculteurs (comme celles qui sont liées aux sols et à l’eau, la lutte intégrée contre les ennemis des cultures, l’agriculture biologique) que les technologies axées sur la science (comme les biotechnologies et l’agriculture de précision). …”

“…The test substance has the potential to impair the junctions of the MDCK cells and thus to increase the monolayer¡ ̄s permeability. …”