“…Un viaje narrado desde el corazón de un proceso de lucha contra el cáncer. Como tantos viajes, en este también hay compañeros de viaje: amigos enfermos, algunos de ellos ya llegaron a su estación; acompañantes en la enfermedad, que comparten las esperanzas y las amarguras; familiares y amigos... …”

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“…The restructuring of nature dominates research in such crucial areas as human reproduction; the growth and distribution of food; the causes and control of medical conditions, from cancer to schizophrenia; the manufacture of drugs; and the development of weapons. …”

“…Goldin argues that although recent public and private discourse has brought these concerns to light, the actions taken-such as a single company slapped on the wrist or a few progressive leaders going on paternity leave-are the economic equivalent of tossing a band-aid to someone with cancer. These solutions, Goldin writes, treat the symptoms and not the disease of gender inequality in the workplace and economy. …”

“…In everything else in their lives, they vary greatly.In this book, you will meet a handful of these men and women, ranging from an American plumber to a Swiss philanthropist and from a Spanish teenager with cancer to a Guatemalan pediatrician who first learned about Opus Dei when he was already fifty-four years old.In these stories, may we all be encouraged and inspired to live a life of deep faith, committed to our call to holiness through the means God has given us --…”

Tabla de Contenidos: “…-- Who gets hurt affects injury recognition -- The type of injury and its cost also affect recognition -- Employers may impede injury recognition -- The social construction of injury and hazards -- Employer tactics in contesting injury recognition -- Perpetuating the careless worker myth -- Identifying occupational cancer -- Preventing occupational cancer -- Constructing cancer as a non-issue…”

Tabla de Contenidos: “…6.1.1 Motion Mechanism of Biological Micro‐ and Nanorobots -- 6.1.1.1 Bacteria -- 6.1.1.2 Sperm -- 6.1.1.3 Immune Cells -- 6.1.2 Motion Mechanism of Physical Field‐Driven Micro‐ and Nanorobots -- 6.1.2.1 Magnetic Field‐Driving Mode -- 6.1.2.2 Photic Driving Mode -- 6.1.2.3 Ultrasonic Field‐Driving Mode -- 6.1.3 Motion Mechanism of Chemical Reaction‐Driven Micro‐ and Nanorobots -- 6.1.3.1 Self‐Electrophoresis Mode -- 6.1.3.2 Self‐Diffusiophoresis Mode -- 6.1.3.3 Bubble Mode -- 6.2 Trend Behavior Mechanism -- 6.2.1 Magnetotactic System -- 6.2.2 Phototactic System -- 6.2.3 Chemotaxis System -- 6.3 Motion Control -- 6.3.1 Speed Control Mode -- 6.3.2 Direction Control Mode -- 6.3.3 Control of Start and Stop -- References -- Chapter 7 Functions -- 7.1 Moving in Complex Physiological Environment -- 7.2 Loading Power Source, Drug, or Imaging Agent -- 7.3 Targeting Specific Cells or Physiological Tissues -- 7.4 Promoting Cell Uptake and Improving Tissue Permeability -- 7.5 Imaging Capability -- 7.6 Information Interaction and Intelligent Decision -- 7.7 Diagnosis and Treatment of Disease -- References -- Chapter 8 For Cardiovascular Disease Treatment -- 8.1 Thrombus -- 8.2 Atherosclerosis -- 8.3 Cerebral Apoplexy -- References -- Chapter 9 For Cancer Treatment -- 9.1 Cancer Diagnosis -- 9.2 Targeting and Delivery -- 9.3 Treatment of Different Cancer Species -- 9.4 Treatment Mechanism -- 9.4.1 Chemotherapy -- 9.4.2 Metabolic Therapy -- 9.4.3 Gas Therapy -- 9.4.4 Optical Therapy -- 9.4.5 Biotherapy -- 9.4.6 Immunotherapy -- 9.4.7 Multimodal Combined Therapy -- 9.5 Theranostics -- References -- Chapter 10 For Other Diseases' Treatment -- 10.1 Ophthalmic Diseases -- 10.2 Orthopedic Diseases -- 10.3 Gastrointestinal Diseases -- 10.4 Neurological Diseases -- 10.5 Bacterial Infection -- 10.6 Blood Heavy Metal Poisoning -- References…”

Tabla de Contenidos: “…Spotted Arrays 9 -- 1.6 Summary 11 -- 1.7 Further Reading 13 -- 2 Overview of Data Analysis 15 -- 3 Basic Data Analysis 17 -- 3.1 Absolute Measurements 17 -- 3.2 Scaling 18 -- 3.2.1 Example: Linear and Nonlinear Scaling 20 -- 3.3 Detection of Outliers 20 -- 3.4 Fold Change 21 -- 3.5 Significance 22 -- 3.5.1 Nonparametric Tests 24 -- 3.5.2 Correction for Multiple Testing 24 -- 3.5.3 Example I: t-Test and ANOVA 25 -- 3.5.4 Example II: Number of Replicates 26 -- 3.6 Summary 28 -- 3.7 Further Reading 29 -- 4 Visualization by Reduction of Dimensionality 33 -- 4.1 Principal Component Analysis 33 -- 4.2 Example 1: PCA on Small Data Matrix 35 -- 4.3 Example 2: PCA on Real Data 37 -- 4.4 Summary 37 -- 4.5 Further Reading 39 -- 5 Cluster Analysis 41 -- 5.1 Hierarchical Clustering 41 -- 5.2 K-means Clustering 43 -- 5.3 Self-Organizing Maps 44 -- 5.4 Distance Measures 45 -- 5.4.1 Example: Comparison of Distance Measures 47 -- 5.5 Normalization 49 -- 5.6 Visualization of Clusters 50 -- 5.6.1 Example: Visualization of Gene Clusters in -- Bladder Cancer 50 -- 5.7 Summary 50 -- 5.8 Further Reading 52 -- 6 Beyond Cluster Analysis 55 -- 6.1 Function Prediction 55 -- 6.2 Discovery of Regulatory Elements in Promoter -- Regions 56 -- 6.2.1 Example 1: Discovery of Proteasomal Element 57 -- 6.2.2 Example 2: Rediscovery of Mlu Cell Cycle -- Box (MCB) 57 -- 6.3 Integration of data 58 -- 6.4 Summary 59 -- 6.5 Further Reading 59 -- 7 Reverse Engineering of Regulatory Networks 63 -- 7.1 The Time-Series Approach 63 -- 7.2 The Steady-State Approach 64 -- 7.3 Limitations of Network Modeling 65 -- 7.4 Example 1: Steady-State Model 65 -- 7.5 Example 2: Steady-State Model on Real Data 66 -- 7.6 Example 3: Steady-State Model on Real Data 68 -- 7.7 Example 4: Linear Time-Series Model 68 -- 7.8 Further Reading 71 -- 8 Molecular Classifiers 75 -- 8.1 Classification Schemes 76 -- 8.1.1 Nearest Neighbor 76 -- 8.1.2 Neural Networks 76 -- 8.1.3 Support Vector Machine 76 -- 8.2 Example I: Classification of Cancer Subtypes 77 -- 8.3 Example II: Classification of Cancer Subtypes 78 -- 8.4 Summary 79 -- 8.5 Further Reading 79 -- 9 Selection of Genes for Spotting on Arrays 81 -- 9.1 Gene Finding 82 -- 9.2 Selection of Regions Within Genes 82 -- 9.3 Selection of Primers for PCR 83 -- 9.4 Selection of Unique Oligomer Probes 83 -- 9.4.1 Example: Finding PCR Primers for Gene -- AF105374 83 -- 9.5 Experimental Design 84 -- 9.6 Further Reading 84 -- 10 Limitations of Expression Analysis 87 -- 10.1 Relative VersusAbsoluteRNA Quantification 88 -- 10.2 Further Reading 88 -- 11 Genotyping Chips 91 -- 11.1 Example: NeuralNetworksfor GeneChipprediction 91 -- 11.2 Further Reading 93 -- 12 Software Issues and Data Formats 95 -- 12.1 Standardization Efforts 96 -- 12.2 Standard File Format 97 -- 12.2.1 Example: Small Scripts in Awk 97 -- 12.3 Software for Clustering 98 -- 12.3.1 Example: Clustering with ClustArray 99 -- 12.4 Software for Statistical Analysis 99 -- 12.4.1 Example: StatisticalAnalysis with R 99 -- 12.4.2 The affyR Software Package 103 -- 12.4.3 Commercial Statistics Packages 103 -- 12.5 Summary 103 -- 12.6 Further Reading 104 -- 13 Commercial Software Packages 105 -- 14 Bibliography 109 -- Index 123.…”
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Información biográfica

Tabla de Contenidos: “…Un cambio de paradigma -- 9. Genómica y cáncer -- 9.1. El cáncer como enfermedad del genoma -- 9.2. …”

Tabla de Contenidos: “…CAPÍTULO 26 VIGILANCIA PARA DISPLASIA Y CÁNCER COLORRECTAL EN COLITIS (...) -- CAPÍTULO 27 ADHERENCIA AL TRATAMIENTO EN ENFERMEDAD INFLAMATORIA INTESTINAL -- CAPÍTULO 28 VACUNAS EN ENFERMEDAD INFLAMATORIA INTESTINAL -- CAPÍTULO 29 CALIDAD DE VIDA EN LOS PACIENTES CON ENFERMEDAD (...) -- CAPÍTULO 30 SOBREPOSICIÓN DE SÍNTOMAS TIPO SÍNDROME DE INTESTINO (...) -- ÍNDICE ALFABÉTICO…”

Tabla de Contenidos: “…Cover; Preface; The RAND Corporation Quality Assurance Process; Contents; Figure and Tables; Summary; Acknowledgments; Abbreviations; CHAPTER ONE; Introduction; Background; National Dialogue on Cancer; RAND Study; Purpose; Description of Study; Organization of This Report; CHAPTER TWO; Methodology; Selection of Repositories; Interviews; Repositories Evaluated; Government; Academia; Industry; Repositories Not Included in the Evaluation; SPOREs; IMPATH Inc.; National Surgical Adjuvant Breast and Bowel Project (NSABP); Program for Critical Technologies in Molecular Medicine…”

Tabla de Contenidos: “…Integrative network analysis to identify aberrant pathway networks in ovarian cancer / Li Chen ... [et al.] -- Role of synthetic genetic interactions in understanding functional interactions among pathways / Shahin Mohammadi, Giorgos Kollias, and Ananth Grama -- Discovery of mutated subnetworks associated with clinical data in cancer / Fabio Vandin ... …”

Tabla de Contenidos: “…Hazards: Technology and Fairness -- Copyright -- PREFACE AND ACKNOWLEDGMENTS -- Contents -- INTRODUCTION: EMERGING ISSUES IN HAZARD MANAGEMENT -- REFERENCE -- PART 1 UNCERTAINTY -- Science and Its Limits: The Regulator's Dilemma -- SCIENCE AND RARE EVENTS -- Scientific" Approaches to Rare Events -- Low-Level Exposure -- Natural Carcinogens -- Ambiguous Carcinogens -- How Science Reacts to Intrinsic Uncertainty -- THE ATTACK ON SCIENCE FROM THE SOCIOLOGY OF KNOWLEDGE -- FINESSING UNCERTAINTY -- Technological Fix -- The De Minimis Principle -- CONCLUSIONS -- REFERENCES -- Causality of a Given Cancer After Known Radiation Exposure -- ACCIDENTAL HARM IN POPULATIONS OF EXPOSED PERSONS -- QUANTAL RESPONSE IN A POPULATION OF HARMED PERSONS -- RADIOTHERAHY OR ACCIDENTAL HIGH-LEVEL RADIATION EXPOSURE -- LOW-LEVEL EXPOSURE OF NORMAL POPULATIONS -- RADIOBIOLOGICAL RESPONSE FUNCTIONS -- PROBABILITY OF CAUSATION IN CANCER CASES -- NOTES -- References -- Dealing With Uncertainty About Risk in Risk Management -- RISK VERSUS UNCERTAINTY -- Risk Assessment Policy -- Is Conservatism Protective? …”

Tabla de Contenidos: “….] -- Mechanisms that generate and maintain bone cancer pain / Juan Miguel Jimenez-Andrade, Monica Herrera, and Patrick W. …”
Enlace del recurso

Tabla de Contenidos: “…Nursing practice and the nursing process -- Standards of care, ethical and legal issues -- Health promotion and preventive care -- Genetics and health applications -- Adult physical assessment -- I.V. therapy -- Perioperative nursing -- Cancer nursing -- Care of the older or disabled adult -- Respiratory function and therapy -- Respiratory disorders -- Cardiovascular function and therapy -- Cardiac disorders -- Vascular disorders -- Neurologic disorders -- Eye disorders -- Ear, nose, and throat disorders -- Gastrointestinal disorders -- Hepatic, biliary, and pancreatic disorders -- Nutritional problems -- Renal and urinary disorders -- Gynecologic disorders -- Breast conditions -- Endocrine disorders -- Diabetes mellitus -- Hematologic disorders -- Transfusion therapy and blood and marrow stem cell transplantation -- Asthma and allergy -- HIV disease and AIDS -- Connective tissue disorders -- Infectious diseases -- Musculoskeletal disorders -- Dermatologic disorders -- Burns -- Emergent conditions -- Maternal and fetal health -- Nursing management during labor and delivery -- Care of mother and neonate during the postpartum period -- Complications of the childbearing experience -- Pediatric growth and development -- Pediatric physical assessment -- Pediatric primary care -- Care of the sick or hospitalized child -- Pediatric respiratory disorders -- Pediatric cardiovascular disorders -- Pediatric neurologic disorders -- Pediatric eye and ear problems -- Pediatric gastrointestinal and nutritional disorders -- Pediatric renal and genitourinary disorders -- Pediatric metabolic and endocrine disorders -- Pediatric oncology -- Pediatric hematologic disorders -- Pediatric immunologic disorders -- Pediatric orthopedic problems -- Pediatric integumentary disorders -- Developmental disabilities -- Problems of mental health…”
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Tabla de Contenidos: “…Marco teórico, medición e hipótesis de estudio / María José Cornejo Cañamares -- Desprofesionalización y exigencias éticas de los trabajadores de la ciencia / Francisco Javier Gómez González -- Dualidad conceptual de las vacunas comestibles: alimento versus medicamento / Muñoz van den Eynde -- Algoritmos híbridos de clasificación aplicados a la detección de casos de cáncer de mama en programas de cribado / Elena Cebadera Miranda y Montaña Cámara Hurtado…”

Tabla de Contenidos: “…ENFERMEDADES NEUROPSIQUIÁTRICAS; 18. CÁNCER; 19. TABAQUISMO; 20. MANEJO ODONTOLÓGICO DEL ADULTO MAYOR; 21. …”

Tabla de Contenidos: “…Frontmatter -- Preface -- Foreword -- Contents -- List of contributing authors -- Part I: Basics -- 1 Brief history of fluorescence lifetime imaging / 2 The long journey to the laser and its use for nonlinear optics / 3 Advanced TCSPC-FLIM techniques / 4 Ultrafast lasers in biophotonics / Part II: Modern nonlinear microscopy of live cells -- 5 STED microscopy: exploring fluorescence lifetime gradients for super-resolution at reduced illumination intensities / 6 Principles and applications of temporal-focusing wide-field two-photon microscopy / 7 FLIM-FRET microscopy / 8 TCSPC FLIM and PLIM for metabolic imaging and oxygen sensing / 9 Laser tweezers are sources of two-photon effects / 10 Metabolic shifts in cell proliferation and differentiation / 11 Femtosecond laser nanoprocessing / 12 Cryomultiphoton imaging / Part III: Nonlinear tissue imaging -- 13 Multiphoton Tomography (MPT) / 14 Clinical multimodal CARS imaging / 15 In vivo multiphoton microscopy of human skin / 16 Two-photon microscopy and fluorescence lifetime imaging of the cornea / 17 Multiscale correlative imaging of the brain / 18 Revealing interaction of dyes and nanomaterials by multiphoton imaging / 19 Multiphoton FLIM in cosmetic clinical research / 20 Multiphoton microscopy and fluorescence lifetime imaging for resection guidance in malignant glioma surgery / 21 Non-invasive single-photon and multi-photon imaging of stem cells and cancer cells in mouse models / 22 Bedside assessment of multiphoton tomography / Index…”

Tabla de Contenidos: “…Pathology of Progress: Cancer, Modernity, and Decline in Nineteenth-Century Britain / Agnes Arnold-Forster -- 9. …”