Tabla de Contenidos: “…Mechanistic Studies -- ASSAYS OF PULMONARY IMMUNOCOMPETENCE -- ASSAYS REQUIRING ADDITIONAL DEVELOPMENT -- USE OF IMMUNOTOXICITY BIOASSAYS -- Considerations in the Design of Immunotoxicity Testing -- Immunotoxicity as a Basis for Risk Assessment -- SUMMARY -- RECOMMENDATIONS -- 7 Human Immune-System Biologic Markers of Immunotoxicity -- TESTS FOR ASSESSING IMMUNITY -- TESTS OF THE HUMORAL IMMUNE SYSTEM -- Immunoglobulin Concentration -- Antibody Formation -- B Cells -- CELLULAR IMMUNE SYSTEM -- Skin Testing -- In Vitro Stimulation of Lymphocytes -- OTHER TESTS -- OPPORTUNITIES FOR DEVELOPMENT OF BIOLOGIC MARKERS THAT ASSESS THE EFFECT OF IMMUNOTOXICANTS -- Primary Humoral Immune Responses -- Activation Antigens on Lymphocyte Surfaces and in Serum -- Synthesis and Secretion of Lymphokines After Lymphocyte Activation -- Proliferative Responses to Super-Antigens -- Self-HLA-Restricted Cell-Mediated Cytotoxicity -- PROPOSED TESTING REGIMEN -- SUMMARY -- RECOMMENDATIONS -- 8 Application of Biologic Markers Of Immunotoxicity in Epidemiology -- EPIDEMIOLOGY -- CONTRIBUTION OF BIOLOGIC MARKERS TO EPIDEMIOLOGY -- VARIABILITY IN REFERENCE POPULATIONS -- SENSITIVITY, SPECIFICITY, AND PREDICTIVE VALUE -- AUTHENTICATION OF THE EVENT STATUS -- STUDY DESIGN -- REFERENCE POPULATIONS -- CASE STUDIES -- Background -- Study Design -- Results -- Strengths -- Limitations -- Background -- Study Design -- Results -- Strengths -- Limitations -- Background -- Study Design -- Results -- Strengths -- Limitations -- Background -- Study Design -- Results -- Strengths -- Limitations -- RECOMMENDATIONS -- 9 Use of Biologic Markers In Controversial Areas Of Environmental Health -- EVIDENCE OF EXPOSURE TO ORGANIC CHEMICALS -- HEALTH EFFECTS OF INDOOR AIR CONTAMINANTS -- CASE DEFINITIONS OF MULTIPLE-CHEMICAL-SENSITIVITY SYNDROME -- IMMUNE-SYSTEM DYSFUNCTION IN MCS PATIENTS…”

Tabla de Contenidos: “…11.3 Elements of a Basic Queueing System -- 11.4 Description of a Queueing System -- 11.5 Classification of Queueing Systems -- 11.6 Queueing Problem -- 11.7 States of Queueing Theory -- 11.8 Probability Distribution in Queueing Systems -- 11.9 Kendall's Notation for ­Representing Queueing ­Models -- 11.10 Basic Probabilistic Queueing Models -- Exercises -- Fill in the Blanks -- Appendix A: Test Based on Normal Distributions -- Appendix B: Statistical Tables -- Appendix C: Basic Results -- Additional Solved Problems -- Index…”

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