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261Publicado 2014Tabla de Contenidos: “…Introduction -- The Roman monster : from pious portent to political pasquinade -- The Roman monster in the Kingdom of Bohemia, 1498-1523 -- The Papal Antichrist -- Philip Melanchthon's The Pope-Ass explained -- The diffusion of the Roman monster within the discourse of the Reformation -- Conclusion -- Appendix: The Pope-Ass explained (1523) / by Philip Melanchthon…”
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Libro electrónico -
262Publicado 1949Tabla de Contenidos: “…v. IV : ARBO-ASSE…”
Libro -
263Publicado 1976Tabla de Contenidos: “…v. V : Arc-Ass…”
Libro -
264por Plauto, Tito MaccioTabla de Contenidos: “…I : Amphitryon ; The comedy of asses ; The pot of gold ; The two bacchises ; The captives. - Indice…”
Publicado 1961
Libro -
265Publicado 1977Tabla de Contenidos:Biblioteca Universidad de Deusto (Otras Fuentes: Biblioteca de la Universidad de Navarra)Libro
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266Publicado 1977Tabla de Contenidos: “…v. III : Cong. Ass. - S. Lunardi…”
Biblioteca Universidad de Deusto (Otras Fuentes: Biblioteca de la Universidad de Navarra)Libro -
267
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268por Organisation for Economic Co-operation and Development.Tabla de Contenidos: “…Classification --(i) "Extra" c;ass --(ii) Class I --(iii) Class II III. Provisions Concerning Sizing IV. …”
Publicado 2010
Libro electrónico -
269por Philbrick, Nathaniel, 1956-Tabla de Contenidos: “…At the flood -- The dream -- Hard ass -- The dance -- The scout -- The blue pencil line -- The approach -- The crow's nest -- Into the valley -- The charge -- To the hill -- Still point -- The forsaken -- Grazing his horses -- The last stand -- The river of nightmares…”
Publicado 2010
Libro -
270
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Libro electrónico -
271por Lleonart, AitanaTabla de Contenidos: “…GCA Arquitectes Ass. (2005) -- QK Boutique, c. Calvet, Arq. GCA Arquitectes Ass. (2007) -- Edifici Forum, Rambla de Prim, Arq. …”
Publicado 2007
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272Publicado 1977Tabla de Contenidos: “…-Communitas T. - III. Cong.Ass S. Lunardi - IV. Maggi D.-Rapallo I.A. - V. …”
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273Publicado 2013Tabla de Contenidos: “…Summary -- Introduction -- 1.1 Protein aggregation and amyloidoses -- 1.1.1 Mechanisms of amyloid fibril formation -- 1.1.2 Oligomer structural polymorphism: fibrillar and prefibrillar oligomers -- 1.1.3 Oligomer toxicity: common mechanism of pathogenesis -- 1.1.4 Amyloid formation is an inherent property of polypeptide chains: functional amyloid and disease unreleated amyloid -- 1.2 HypF-N: model protein of amyloid aggregation unrelated to disease -- 1.2.1 Function, structure and aggregation of HypF-N -- 1.2.2 HypF-N protofibrils interact with cell membranes originating a cytotoxic cascade -- 1.2.3 A causative link between the structure of HypF-N oligomers and their ability to cause cellular dysfunction -- 1.3 Alzheimer's disease -- 1.3.1 The Alzheimer phenotype -- 1.3.2 The elaborate processing of APP -- 1.3.3 The genetics of Alzheimer's disease -- 1.3.4 Peripheral cells as a tool to identify and test hypotheses on AD pathophysiology -- 1.3.5 Adult neurogenesis and stem cell technology for AD -- 1.4 Cholesterol and gangliosides in the central nervous system (CNS) -- 1.4.1 Brain cholesterol metabolism -- 1.4.2 Ganglioside metabolism -- 1.4.3 Lipid rafts -- 1.4.4 Role of cholesterol in AD -- 1.4.5 Role of gangliosides in AD -- 1.5 Aim of the study -- Materials & Methods -- 2.1 Materials -- 2.1.1 Chemicals -- 2.1.2 Fluorescent probes -- 2.1.3 Peptides and aggregation protocols -- 2.2 Cell cultures -- 2.3 Methods -- 2.3.1 Separation processes -- 2.3.2 Differentiation of human mesenchymal stromal cells -- 2.3.3 Modulation of membrane cholesterol levels -- 2.3.4 Modulation of membrane GM1 levels -- 2.3.5 Cholesterol content measurements -- 2.3.6 GM1 content measurements -- 2.3.7 Cell exposure to peptide aggregates -- 2.3.8 Analysis of aggregate interaction with the cells -- 2.3.9 Analysis of aggregate interaction with GM1 -- 2.3.10 Analysis of aggregate internalisation -- 2.3.11 Analysis of membrane permeability -- 2.3.12 Analysis of cytosolic Ca2+ dyshomeostasis -- 2.3.13 Evaluation of ROS production -- 2.3.14 Analysis of lipid peroxidation -- 2.3.15 Cytotoxicity assay and cell death analysis: apoptotic and necrotic markers -- 2.3.16 Steady-state fluorescence anisotropy -- 2.3.17 Atomic force microscopy (AFM) -- 2.3.18 Measurements of the fluorescence intensities -- 2.3.19 Statistical analysis -- Results -- 3.1 Results I -- 3.1.1 A protective role for lipid raft cholesterol against amyloidinduced membrane damage in human neuroblastoma cells -- 3.1.2 Aß42 oligomer binding to the cell surface and its cytotoxic effect are modulated by membrane cholesterol content -- 3.1.3 Aß42 oligomers colocalize with lipid rafts -- 3.1.4 Isolation and characterization of DRMs -- 3.1.5 Effects of ADDLs on lipid raft structural order -- 3.1.6 AFM imaging of supported DRMs purified from cells exposed to ADDLs -- 3.2 Results II -- 3.2.1 Lipid rafts mediate amyloid-induced calcium dyshomeostasis and oxidative stress in Alzheimer's disease -- 3.2.2 Lipid rafts are primary interaction sites for Aß42 oligomers at the plasma membrane -- 3.2.3 Cholesterol and GM1 mediate Aß42 accumulation at the plasma membrane -- 3.2.4 Cholesterol and GM1 mediate Ca2+ dyshomeostasis and extensive membrane permeabilization induced by Aß42 oligomers -- 3.2.5 GM1 modulates lipid peroxidation and cytotoxicity induced by Aß42 oligomers -- 3.2.6 GM1 mediates Aß42-induced Ca2+ dyshomeostasis, lipid peroxidation and cytotoxicity in rat cortical neurons -- 3.3 Results III -- 3.3.1 Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers -- 3.3.2 Membrane cholesterol content modulates oligomer cytotoxicity -- 3.3.3 Membrane cholesterol modulates oligomer-induced alteration of intracellular Ca2+ homeostasis and ROS levels -- 3.3.4 Cholesterol levels modulate membrane permeability to the oligomers -- 3.3.5 Membrane GM1 affects the cytotoxic and permeabilizing effects of HypF-N oligomers -- 3.3.6 GM1, rather than cholesterol, plays a dominant role in oligomer cytotoxicity and membrane permeability -- 3.4 Results IV -- 3.4.1 Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aß42 aggregate toxicity -- 3.4.2 Neuronal differentiation of hMSCs results in reduced levels of membrane GM1 -- 3.4.3 Neuronal differentiation of hMSCs reduces the interaction of Aß42 oligomers with the cell surface -- 3.4.4 Neuronal differentiation of hMSCs reduces Aß42 oligomerinduced intracellular Ca2+ dyshomeostasis and oxidative stress -- 3.4.5 Neuronal differentiation of hMSCs increases cell resistance to Aß42 aggregates Discussion -- 4.1 A protective role for lipid raft cholesterol against amyloid-induced membrane damage in human neuroblastoma cells -- 4.2 Lipid rafts mediate amyloid-induced calcium dyshomeostasis and membrane permeabilization in Alzheimer's fibroblasts -- 4.3 Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers -- 4.4 Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aß42 aggregate toxicity -- 4.5 Concluding remarks -- Abbreviations -- References…”
Libro electrónico -
274Publicado 2004Tabla de Contenidos: “…Fundamentals -- Choosing and buying components -- Building a mainstream PC -- Building a SOHO server -- Building a kick-ass LAN party PC -- Building a home theater PC -- Building a small form factor PC…”
Libro electrónico -
275Publicado 2017Tabla de Contenidos: “…Conté: Picasso and the "Primitive Arts" 1900-1974 : chronology, pàgina 13 -- Body to body : archaisms metamorphoses the id, pàgina 109 -- The Essays, pàgina 281 -- Nothing but the primitive / Yves Le Fur -- Beneath the painting / Gérard Wajcman -- Louise's ass / Stéphane Breton…”
Libro -
276Publicado 2002Tabla de Contenidos: “…Cover; Half Title; Title Page; Copyright Page; Table of Contents; Editorial Note; The Tale: Amor and Psyche, from the Metamorphoses or Golden Ass of Lucius Apuleius; Amor and Psyche; The Commentary: The Psychic Development of the Feminine; Forenote; The Psychic Development of the Feminine; Postscript; List of Works Cited; Index…”
Biblioteca Universitat Ramon Llull (Otras Fuentes: Universidad Loyola - Universidad Loyola Granada, Biblioteca de la Universidad Pontificia de Salamanca)Libro electrónico -
277Publicado 1977Tabla de Contenidos: “…-Communitas T. -- vol. 3. Cong. Ass.-S. Lunardi -- vol. 4. Maggi D.-Rapallo I.A. -- vol. 5. …”
Libro -
278Publicado 1977Tabla de Contenidos: “…-Communitas T. -- vol. 3. Cong. Ass.-S. Lunardi -- vol. 4. Maggi D.-Rapallo I.A. -- vol. 5. …”
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279Publicado 1974Libro
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280por Budé, Guillaume, 1468-1540Tabla de Contenidos: “…III, Epistolarum Graecarum lib. I --T. II: De Asse et partibus eius libri V -- T. III: Annotationes in Pandectas tam priores -- T. …”
Publicado 1557
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