The gut microbiota in health and disease
Otros Autores: | , , , |
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Formato: | Libro electrónico |
Idioma: | Inglés |
Publicado: |
Hoboken, New Jersey:
John Wiley & Sons, Incorporated
2023.
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Materias: | |
Ver en Universidad de Navarra: | https://unika.unav.edu/discovery/fulldisplay?docid=alma991011528135308016&context=L&vid=34UNAV_INST:VU1&search_scope=34UNAV_TODO&tab=34UNAV_TODO&lang=es |
Tabla de Contenidos:
- Intro
- The Gut Microbiota in Health and Disease
- Contents
- List of Contributors
- 1 Structural and Dynamics of Healthy Adult's Microbiota
- 1.1 Introduction
- References
- 2 Composition and Diversity of Gut Microbiota
- 2.1 Introduction
- 2.2 Composition and Diversity of Gut Microbiota Throughout Lifespan
- 2.3 Composition of Bacterial Community in the Different Sections of the Gastrointestinal Tract
- 2.4 Stability, Resilience, and Functional Redundancy
- 2.5 Interactions in the Gut Microbiota
- 2.5.1 Microbe-microbe Interactions
- 2.5.2 Host-microbe Interactions
- 2.5.3 Colonisation of the Gut Microbiota
- 2.6 Conclusion
- References
- 3 Factors Affecting Composition and Diversity of Gut Microbiota: A Disease Hallmark
- 3.1 Introduction
- 3.2 Composition of Gut Microbiota
- 3.2.1 Gut Microbiota of Infants and Newborns
- 3.2.2 Gut Microbiota of Adults
- 3.3 Factors Affecting Gut Microbiota
- 3.3.1 Age and Delivery Pattern
- 3.3.2 Diet
- 3.3.3 Antibiotics
- 3.3.4 Oxidative Stress
- 3.4 Modulation of Gut Microbiota
- 3.4.1 Probiotics and Prebiotics
- 3.5 Gut Microbiota Hallmark in Disease Condition
- 3.5.1 Cancer
- 3.5.2 COVID-19
- 3.5.3 HIV
- 3.6 Conclusion
- References
- 4 Antibiotic-Induced Changes in the Composition of the Gut Microbiome
- 4.1 Introduction
- 4.2 Gut Microbiota Composition
- 4.3 Antibiotic-induced Changes in the Composition of the Microbiota
- 4.3.1 Loss of Bacterial Diversity and Domination of Pathogenic Bacteria
- 4.3.2 Decrease or Loss of Certain Bacterial Species
- 4.3.3 Increase in Susceptibility to Infections and Diseases
- 4.4 Conclusion
- References
- 5 Dysbiosis and its Varied Impacts
- 5.1 Introduction
- 5.2 Causes of Dysbiosis
- 5.3 Dysbiosis, Immune System, and Associated Diseases
- 5.3.1 Dysbiosis in the Immune-Compromised Host.
- 5.3.2 Intestinal Bowel Disease (IBD)
- 5.3.3 Rheumatoid Arthritis
- 5.3.4 Type 1 Diabetes
- 5.3.5 Dysbiosis of Skin Microbiome in Carcinogenesis
- 5.3.6 Dysbiosis of Oral Microbiota Impacts Carcinogenesis
- 5.3.7 Dysbiosis of Urobiome
- 5.3.8 Pigmented Gallstone
- 5.3.9 Cholangitis
- 5.4 Intestinal Colonisation in Neonates and Dysbiosis
- 5.5 Treatment or Therapeutics
- 5.6 Conclusion
- References
- 6 Connection between Dysbiosis and Diet
- 6.1 Introduction
- 6.1.1 Gut Microbiota and Dysbiosis
- 6.1.2 Importance of Diet in regulation of Gut Microbiota
- 6.2 Different Dietary Patterns Resulting in Dysbiosis
- 6.2.1 Breastfeeding
- 6.2.2 Carbohydrate-rich Diet
- 6.2.3 Protein-rich Diet
- 6.2.4 Fats and Oil-rich Diet
- 6.3 Future Prospects in Establishing a Healthy Connection between Diet and Gut Microbiota
- 6.4 Conclusion
- References
- 7 Composition of Gut Microbiota and Clostridium difficile
- 7.1 Introduction
- References
- 8 Gut Microbiota and Obesity
- 8.1 Introduction
- 8.2 Obesity Epidemic: Statistics and General Background
- 8.3 Gut Microbiota and Obesity
- 8.4 Adiposity and Gut Microbiota
- 8.4.1 Short Chain Fatty Acids (SCFAs)
- 8.4.2 AMPK and FIAF
- 8.4.3 Bile Acids
- 8.4.4 Lipopolysaccharides (LPS)
- 8.5 Gut Microbiota Modification
- 8.5.1 Diet
- 8.5.2 Age
- 8.5.3 Antibiotics
- 8.5.4 Probiotics
- 8.6 The Microbiota and Obesity Interactions
- 8.6.1 Immune System
- 8.6.2 Lipid Metabolism
- 8.6.3 Satiety Hormones
- 8.6.4 Nutrient Metabolism
- 8.6.5 Lymphoid Structures
- 8.6.6 Microbiota-Adipose Tissue Axis
- References
- 9 Gut Microbiota and Cardiovascular Disease
- 9.1 Introduction
- 9.2 Gut Microbiota and CVD
- 9.2.1 Role of TMAO in Coronary Heart Disease
- 9.3 Gut Microbiota Composition in Cardiovascular Disease
- 9.4 Gut Microbiota Function in Cardiovascular Disease.
- 9.5 Gut Microbiota as Therapeutic Strategies for Cardiovascular Disease
- 9.5.1 Probiotics
- 9.5.2 Fecal Microbiota Transplantation
- References
- 10 Gut Microbiota and Inflammatory Bowel Diseases
- 10.1 Introduction
- 10.2 Intestinal Microbiome in IBD Patients
- 10.2.1 Dysbiosis in IBD
- 10.2.2 Genetic Factors of the Host Affecting the Pathogenesis of IBD
- 10.2.3 Environmental Factors in the Disruption of Gut Microbiota and Development of IBD
- 10.3 Interventions for the Treatment of IBD
- 10.3.1 Microbiome-modulating Approach in the Treatment of IBD
- 10.4 Conclusion
- References
- 11 Gut Microbiota and Diabetes
- 11.1 Introduction
- 11.2 Gut Microbiota
- 11.3 Role of Gut Microbiota in Diabetes
- 11.4 Alteration in Gut Microbiota Composition in T1 and T2 Diabetes
- 11.4.1 T1D
- 11.4.2 Type 2 Diabetes
- 11.5 Diabetic Complications
- 11.5.1 Diabetic Retinopathy
- 11.5.2 Diabetic Nephropathy
- 11.5.3 Diabetic Neuropathy
- 11.6 Therapeutic Approaches
- 11.7 Conclusion
- References
- 12 Novel Therapeutic Strategies Targeting Gut Microbiota to Treat Diseases
- 12.1 Introduction
- 12.2 Changes in the Composition of the Gut Microbiota in Patients with T1D
- 12.3 The Potential Role of the Gut Microbiota in the Development of T1D
- 12.4 Changes in the Composition of the Gut Microbiota in Patients with T2D
- 12.5 The Potential Role of the Gut Microbiota in the Development of T2D
- 12.7 Preventive and Therapeutic Perspectives Including the Gut Microbiota
- References
- 13 Understanding the Role of Microbiota in Cancer
- 13.1 Introduction
- 13.2 Role of Microbiota in Cancers
- 13.2.1 Gastric Cancer
- 13.2.2 Colorectal Cancer
- 13.2.3 Liver Cancer
- 13.2.4 Pancreatic Cancer
- 13.3 Mechanism in which Microbiota Kill Cancer Cells
- 13.4 Microbiota that Promote Health Post Cancer Treatment
- 13.5 Conclusion.
- References
- 14 Impact of Gut Microbiota on Mental Health in Humans
- 14.1 Introduction
- 14.1.1 Importance of Gut Microbiota
- 14.1.2 The Microbiota-Gut-Brain Axis
- 14.2 Gut Dysbiosis and Mental Health Disorders
- 14.2.1 Neurodevelopmental Disorders
- 14.2.2 Mood Disorders
- 14.2.3 Depression Disorders
- 14.2.4 Alcohol Use Disorder (AUD)
- 14.3 Psychiatric Medication and the Microbiome
- 14.4 Probiotic Treatments for Mental Health Disorders
- 14.5 Future Therapeutic Approach
- 14.6 Conclusion
- References
- 15 Interaction between Gut Microbiota and Central and Enteric Nervous Systems: The Gut-Brain Axis Concept
- 15.1 Introduction
- 15.2 The Neuronal Communications
- 15.3 Neuroimmune Regulation of Inflammation and Cellular Defence
- 15.3.1 Involvement of Microbiota in the Development of the Nervous and Immune Systems and Modulation of Inflammation
- 15.3.2 The Importance of Microbiota for the Development of the Nervous and Immune Systems
- References
- 16 Immune-Modulation and Gut Microbiome
- 16.1 Introduction
- 16.2 Dysbiosis of the Gut Microbiome
- 16.3 Gut Dysbiosis and Diseases
- 16.3.1 Inflammatory Bowel Disease
- 16.3.2 Non-alcoholic Fatty Liver Disease
- 16.4 Gut Microbiome-Mediated Immune Modulation
- 16.4.1 Innate Immunity
- 16.4.2 Adaptive Immunity
- 16.5 Gut Microbiome Modulators
- 16.5.1 Diet
- 16.5.2 Diet, Gut Microbiome, and Immunity
- 16.5.3 Short-Chain Fatty Acids
- 16.6 Prebiotics
- 16.7 Probiotics
- 16.8 Galectins, Gut Microbiome, and Immune Modulation
- 16.9 Conclusion
- References
- 17 Current Molecular Technologies for Assaying the Gut Microbiota: Next-generation DNA Sequencing
- 17.1 Introduction and Overview
- 17.2 Research on the Gut Microbiome Using Next-generation Sequencing
- 17.2.1 Amplicon Sequencing
- 17.2.2 Shotgun Metagenomic and RNA Sequencing.
- 17.2.3 Comparisons between NGS Methods
- 17.3 Collection, Storage, and DNA Extraction Methodology
- 17.3.1 Sample Collection and Storage
- 17.3.2 DNA Extraction and Quantification
- 17.4 DNA Sequencing and Post-processing
- 17.5 Metabolic Modelling of the Human Gut Microbiome
- References
- 18 The Role of Probiotics and Prebiotics in Gut Modulation
- 18.1 Introduction
- 18.2 Probiotics and Prebiotics: A Functional Perspective
- 18.3 Diet and its Effect on Gut Microbiota
- 18.4 Modification of Intestinal Microbiota by the Application of Probiotics and Prebiotics
- 18.4.1 Dysbiosis and Human Diseases
- 18.4.2 How Probiotics Alter the Intestinal Microbiota
- 18.4.3 Probiotics and Intestinal Immunomodulation
- 18.4.4 Probiotics and Prebiotics on Intestinal Neuroimmunology
- 18.5 Prebiotics and Gut Immunity
- 18.5.1 Effects (Direct and Indirect) of Prebiotics on the Immune System
- 18.6 Conclusions and Future Research
- References
- 19 Probiotics, Prebiotics, and Synbiotics: A Potential Source for a Healthy Gut
- 19.1 Introduction
- 19.2 Prebiotics
- 19.2.1 Types of Prebiotics
- 19.2.2 Functioning of Prebiotics
- 19.3 Probiotics
- 19.3.1 Characteristics of Probiotics
- 19.3.2 Mechanisms of Action of Probiotic Strains
- 19.3.3 Applications of Probiotics
- 19.4 Synbiotics
- 19.4.1 Selection Criteria
- 19.4.2 Mechanism of Action
- 19.4.3 Therapeutic Actions
- 19.5 Conclusion
- References
- 20 Current Status and Efficacy of Fecal Microbiota Transplantation for Patients Suffering from Irritable Bowel Syndrome
- 20.1 Introduction
- 20.2 Donor Selection
- 20.3 Safety Issues of FMT for IBS
- 20.4 Possible Mechanisms Underlying the Effects of FMT
- 20.5 Conclusion and Perspective
- References
- Index
- EULA.