Immunotoxicology strategies for pharmaceutical safety assessment
| Otros Autores: | , |
|---|---|
| Formato: | Libro |
| Idioma: | Inglés |
| Publicado: |
Hoboken, N.J. :
Wiley
cop. 2008.
|
| Materias: | |
| Ver en Universidad de Navarra: | https://unika.unav.edu/discovery/fulldisplay?docid=alma991007792339708016&context=L&vid=34UNAV_INST:VU1&search_scope=34UNAV_TODO&tab=34UNAV_TODO&lang=es |
Tabla de Contenidos:
- Current regulatory expectations for immunotoxicologyy evaluation of pharmaceuticals / Kenneth L. Hastings
- Clinical pathology as crucial insight into immunotoxicity testing / Ellen Evans
- Histomorphology of the immune system : a basic step in assessing immunotoxicity / Patrick Haley
- Need for specialized immunotoxicity tests / Kazuichi Nakamura
- Specific drug-induced immunotoxicity : immune-mediated hemolytic anemia / Raj Krishnaraj
- T cell-dependent antibody response tests / Joseph R. Piccotti
- Natural killer cell assay and other innate immunity tests / Lisa Plitnick
- Cellular immune response in delayed-type hypersensitivity test / Karen Price
- Evaluation of drug effects on immune cell phenotypes / Laurie Iciek
- Functional cellular responses and cytokine profiles / Elizabeth R. Gore
- Application of flow cytometry in drug development / Padma Narayanan ... [et al.]
- Animal models of host resistance / Gary R. Burleson and Florence G. Burleson
- Approaches to evaluation of autoimmunity / Danuta J. Herzyk
- Differentiating between desired immunomodulation and potential immunotoxicity / Jeanine L. Bussiere and Barbara Mounho
- Relevant immune tests across different species and surrogate models / Jeanine L. Bussiere
- Antidrug antibody responses in nonclinical studies and their implications / Barbara Mounho
- Pharmacological immunogenicity and adverse responses to vaccines / Mary Kate Hart, Mark Bolanowski, and Robert V. House
- Immunotoxicological concerns for vaccines and adjuvants / Catherine Kaplanski ... [et al.]
- Systemic hypersensitivity / Raymond Pieters
- Nonclinical models to assess respiratory hypersensitivity potential / Curtis C. Maier
- Developmental immunotoxicity in rodents / Rodney R. Dietert and Leigh Ann Burns-Naas
- Developmental immunotoxicity in nonhuman primates / Pauline L. Martin and Eberhard Buse
- Alternative animal models for immunomodulation and immunotoxicity / Peter J. Bugelski
- Animal models for preclinical comparative immunogenicity testing / Daniel Wierda
- T cell epitopes and minimization of immunogenicity / Harald Kropshoffer and Thomas Singer
- Bridging immunotoxicology to clinical drug development / Ian Gourley and Jacques Descotes.
