Tabla de Contenidos:
  • Modulation of β-amyloid production and fibrillization
  • Alzheimer's disease: inside, outside, upside down
  • The role of post-translational modification in β-amyloid precursor protein proessing
  • Alzheimer's disease: dysfunction of a signalling pathway mediated by the amyloid precursor protein?
  • Genetic dissection of primary neurodegenerative diseases
  • Tau gene mutations and neurodegeneration
  • Sites of phosphorylation in tau and factors affecting their regulation
  • Neurofibrillary tangles and tau phosphorylation
  • Presenilin function: connections to Alzheimer's disease and signal tranduction
  • Apolipoprotein E and Alzheimer's disease: signal transduction mechanisms
  • Apolipoprotein E gene and Alzheimer's disease: is tau the link?
  • Apolipoprotein E and βA4-amyloid: signals and effects
  • Regulation of gene expression by muscarinic acetylcholine receptors
  • Oxidative signalling and inflammatory pathways in Alzheimer's disease
  • Perturbed endoplasmic reticulum function, synaptic apoptosis and the pathogenesis of Alzheimer's disease
  • Recetptor-G-protein signalling in Alzheimer's Disease
  • Dysfunctional intracellular calcium homoeostasis: a central cause of neurodegeneration in Alzheimer's disease
  • Transgenic mouse models of Alzheimer's disease: phenotype and mechanisms of pathogenesis
  • Modelling Alzheimer's disease in multiple transgenic mice.