Analysis of aggregates and particles in protein pharmaceuticals

Detalles Bibliográficos
Otros Autores: Mahler, Hanns-Christian (-), Jiskoot, Wim
Formato: Libro electrónico
Idioma:Inglés
Publicado: Hoboken, N.J. : John Wiley & Sons, Inc 2012.
Materias:
Acceso en línea:https://recursos.uloyola.es/login?url=https://accedys.uloyola.es:8443/accedix0/sitios/ebook.php?id=179199
Ver en Universidad Loyola - Universidad Loyola Granada:https://colectivo.uloyola.es/Record/ELB179199
Solicitar por préstamo interbibliotecario: Correo
Tabla de Contenidos:
  • The critical need for robust assays for quantitation and characterization of aggregates of therapeutic proteins
  • Separation based analytical methods for measuring protein aggregation
  • Laser light scattering-based techniques used for the characterization of protein therapeutics
  • Online detection methods and emerging techniques for soluble aggregates in protein pharmaceuticals
  • Analytical methods to measure sub-visible particulates
  • Detection of visible particles in parenteral products
  • Characterization of aggregates and particles using emerging techniques
  • Ultraviolet absorption spectroscopy
  • Fluorescence spectroscopy to characterize protein aggregates and particles
  • Infrared spectroscopy to characterize protein aggregates
  • Raman microscopy for characterization of particles
  • Microscopic methods for particle characterization in protein pharmaceuticals
  • Comparison of methods for soluble aggregate detection and size characterization
  • Protein purification and its relation to protein aggregation and particles
  • Formulation development and its relation to protein aggregation and particles.