Integrated cardiac safety : assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance

Integrated cardiac safety assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance

Detalles Bibliográficos
Autor principal: Turner, J. Rick (-)
Otros Autores: Durham, Todd A.
Formato: Libro electrónico
Idioma:Inglés
Publicado: Hoboken, N.J. : John Wiley & Sons c2009.
Materias:
Cardiovascular toxicology.
Heart > Effect of drugs on.
Drugs > Side effects > Testing.
Drugs > Safety measures.
Electronic books.
Acceso en línea:https://recursos.uloyola.es/login?url=https://accedys.uloyola.es:8443/accedix0/sitios/ebook.php?id=178306
Ver en Universidad Loyola - Universidad Loyola Granada:https://colectivo.uloyola.es/Record/ELB178306
Solicitar por préstamo interbibliotecario: Correo
Tabla de Contenidos:
  • The importance of cardiac safety assessments
  • The biological basis of adverse drug reactions
  • Cardiac structure and function
  • Cardiac pathophysiology and disease
  • Drug discovery and drug design
  • Nonclinical development
  • The thorough QT/QTc trial
  • General safety assessments
  • Therapeutic use trials and meta-analyses
  • Assessment methodologies in nonexperimental postmarketing surveillance
  • Postmarketing proarrhythmic cardiac safety assessments
  • Generalized cardiac safety
  • Medication errors, adherence, and concordance
  • Future directions in drug safety.

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