Principles and Practice of Emergency Research Response
Robust global health security requires effective preparation for and response to emerging and re-emerging pathogens. The nascent field of emergency research response and preparedness is a crucial component in preventing and mitigating outbreaks, yet it is rife with critical scientific, ethical, and...
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| Otros Autores: | , , , , |
| Formato: | Libro electrónico |
| Idioma: | Inglés |
| Publicado: |
Cham :
Springer International Publishing
2024.
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| Edición: | 1st ed. 2024. |
| Materias: | |
| Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009850343106719 |
Tabla de Contenidos:
- Section I. Pandemic Preparedness and Research Response: A Necessary New Field
- 1. Introduction
- 2. Clinical Research on Infectious Diseases
- 3. Guiding Principles for Emergency Research Response
- Section II. Norms for Emergency Research Response
- 4. Ethics of Pandemic Research
- 4.1. In Practice: Vaccine Efficacy and Safety Testing - An Ethical Case for Individual Randomization
- 4.2. In Practice: Research Ethics Committee Review in Public Health Emergencies
- 5. Health Emergency Research amid Global Inequities
- 6. Meeting Regulatory Criteria and Seeking Licensure
- 7. Research, Sample, and Data Sharing During Outbreaks, Pandemics, and Beyond
- Section III. Preparedness for Emergency Research Response
- 8. Building Biomedical Research Capacity in Low- and Middle-Income Countries
- 9. Laboratory Needs for Research Response
- 10. Understanding How and Where Pathogens Emerge
- 11. Accelerating Diagnostic Innovation for Pandemic Control
- 12. Vaccine Candidates for Novel Pathogens.-12.1. In Focus: Novel Manufacturing Platforms for Pandemic Preparedness and Emergency Response
- 13. Accelerating Vaccine Development
- 14. Accelerating Development of Therapeutics for Preparedness, Response, and a More Secure World
- 14.1. In Practice: The RECOVERY Trial
- Section IV. Research Response
- 15. ACTIV: A U.S. Public-Private Partnership Responds to COVID-19
- 15.1. In Practice: Leveraging an Integrated National Health System for Research Response
- 16. Challenges for Emergency Research Interventions in Fragile, Weak, and Failed Nation States
- 16.1. In Practice: Responding to an Infectious Disease Outbreak amid a Humanitarian Emergency
- 17. Integrating Clinical Research into Ebola Response: Liberia Case Study
- 17.1. In Practice: Integration of Clinical Research and Patient Care in the DRC PALM Ebola Therapeutics Trial
- 18. Good Participatory Practice. Social Mobilization, Communications, and Community Engagement
- 18.1. In Practice: Building Community Engagement for Clinical Research Response
- 18.2. In Practice: Adapting Social Analytics for Research Response
- 19. Understanding and Reporting the Natural History of an Infectious Disease
- 20. Turning Research Results into Clinical Practice Guidelines in Public Health Emergencies
- Section V. Methodology for Research Response
- 21. Epidemiological Research in the Setting of Outbreak Response
- 21.1. In Focus: The Impact and Mechanisms of Superspreading
- 22. Vaccine Trial Designs
- 22.1. In Focus: Ring Trial Design
- 23. Data and Safety Monitoring of Clinical Trials During Public Health Emergencies
- 23.1. In Practice: Monitoring the PALM Ebola Therapeutics Study in the Democratic Republic of the Congo
- 24. Mathematical Modeling for Emergency Response
- 25. Models in the COVID-19 Pandemic
- 25.1. Case Study: Modeling Fractional-Dose Emergency Vaccination Campaigns for Yellow Fever
- 26. Social Science Evidence for Outbreak and Pandemic Response
- Section VI. Governance, Institutions, and Partnerships
- 27. A Global Framework for Research Preparedness and Response
- 28. Financing Emergency Research Response during Infectious Disease Outbreaks
- 29. International Collaboration to Advance Research Preparedness and Response
- 30. Organizational Partnerships for Preparedness and Response to Emerging and Re-Emerging Infectious Diseases
- 30.1. In Focus: Research and Medical Humanitarian NGOs
- 30.2. In Practice: Building and Maintaining Preparedness for a Rapid Research Response in Indonesia
- Section VII. Research Operations
- 31. Operational Recommendations for Streamlining Emergency Research Responses to Pandemics
- 32. Launching a Clinical Research Operation
- 32.1. In Practice: Clinical Research Communications During an Outbreak
- 32.2. In Focus: Clinical Trial Insurance and Indemnification
- 33. Ethical Review of Research During an Emergency Response
- 33.1. In Practice: Ethical Review During Emergencies - The Liberian Experience
- 33.2. In Practice: Independent Monitoring of Emergency Response Clinical Trials
- 33.3. In Practice: Capacity Building for Research Ethics Review in Low- and Middle-Income Countries
- 34. Information and Communications Technology to Support Research Low-Resource Settings
- 35. Data Management in Emergency Response Research
- 36. Safety and Pharmacovigilance in Emergency Research Response
- 37. Supply and Logistics for Clinical Research in Low-Resource Settings
- 38. Pharmaceutical Management
- 39. Cold Chain and Electrical Power for Emergency Research Response
- 40. Selecting and Opening a Clinical Research Site in a Low-Resource Setting
- 40.1. In Practice: Improving Patient Care in the Field - The CUBE Isolation Unit
- 41. Management of Security for Clinical Trials During Emergencies
- 42. Locally Hired Staff for Clinical Research Sites in Low-Resource Settings.
