Education and training in the care and use of laboratory animals a guide for developing institutional programs
Autor Corporativo: | |
---|---|
Formato: | Libro electrónico |
Idioma: | Inglés |
Publicado: |
Washington, D.C. :
National Academy Press
1991.
|
Edición: | 1st ed |
Materias: | |
Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009820336906719 |
Tabla de Contenidos:
- Education and Training in the Care and Use of Laboratory Animals
- Copyright
- Preface
- Contents
- I INTRODUCTION
- 1 Introduction
- Reference
- 2 How to Use this Guide
- II COURSE MODULES
- 1 Core Module
- INTRODUCTION
- OUTLINE FOR THE CORE MODULE
- Laws, Regulations, and Policies that Impact on the Care and Use of Animals
- Ethical and Scientific Issues
- Alternatives
- Responsibilities of the Institution, the Animal Care and Use Committee, and the Research and Veterinary Staffs
- Pain and Distress
- Anesthetics, Analgesics, Tranquilizers, and Neuromuscular Blocking Agents
- Survival Surgery and Postsurgical Care
- Euthanasia
- Husbandry, Care, and the Importance of the Environment
- Resources
- 2 Species-Specific Module
- INTRODUCTION
- OUTLINE FOR THE SPECIES-SPECIFIC MODULE
- Selection and Procurement of Animals
- Husbandry and Care
- Handling and Restraint
- Identification and Records
- Animal Health
- Safety and Health Considerations (Zoonoses)
- Specific Techniques
- Euthanasia
- Skill Building
- 3 Pain-Management Module
- INTRODUCTION
- OUTLINE FOR THE PAIN-MANAGEMENT MODULE
- Definitions, Mechanisms, and Assessment
- Legal and Ethical Obligations
- Alleviation of Pain or Distress
- Anesthesia
- Euthanasia
- Skill Building
- 4 Surgery Module
- INTRODUCTION
- OUTLINE FOR THE SURGERY MODULE
- Definitions
- Legal Requirements for Survival Surgery
- Aseptic Technique
- Selection and Administration of Anesthetic
- Surgical Complications
- Surgical Techniques
- Postsurgical Care
- Medical Records
- Terminal Surgeries
- Skill Building
- III CONTENT OUTLINES
- Introduction
- 1 Laws, Regulations, and Policies That Impact on the Care and Use of Animals
- 1.1 FEDERAL REGULATIONS AND POLICIES AFFECTING THE CARE AND USE OF ANIMALS IN RESEARCH, TESTING, AND EDUCATION.
- 1.2 SELECTED REQUIREMENTS OF AWRS AND PHS POLICY
- 1.3 STATE AND LOCAL REGULATIONS AFFECTING THE CARE AND USE OF ANIMALS IN RESEARCH, TESTING, AND EDUCATION…
- 1.4 INSTITUTIONAL POLICIES AFFECTING THE CARE AND USE OF ANIMALS IN RESEARCH, TESTING, AND EDUCATION
- REFERENCES
- 2 Ethical and Scientific Issues
- 2.1 DEFINITIONS
- 2.2 CONCEPTUAL FRAMEWORK FOR ETHICAL DECISIONS (ROBB, 1989)
- 2.3 ARGUMENTS USED BY THOSE ADVOCATING THE HUMANE USE OF ANIMALS FOR HUMAN PURPOSES (CAPLAN, 1984)
- 2.4 ARGUMENTS USED BY ANIMAL-RIGHTS ADVOCATES (SINGER, 1975
- REGAN, 1983)
- 2.5 THE ROLE OF LAWS, REGULATIONS, AND POLICIES
- 2.6 SUGGESTED ETHICAL PRINCIPLES (SEE U.S. GOVERNMENT PRINCIPLES FOR THE UTILIZATION AND CARE OF VERTEBRATE ANIMALS USED IN…
- REFERENCES
- 3 Alternatives
- 3.1 DEFINITIONS
- 3.2 RATIONALE FOR CONSIDERING ALTERNATIVES
- 3.3 NONANIMAL RESEARCH METHODS AND MODELS
- 3.4 FACTORS INFLUENCING MODEL SELECTION
- 3.5 UTILIZATION OF SERVICES
- REFERENCES
- 4 Responsibilities of the Institution, the Animal Care and Use Committee, and the Research and Veterinary Staffs
- 4.1 RESPONSIBILITIES OF THE INSTITUTION
- 4.2 RESPONSIBILITIES OF THE INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC)
- 4.3 RESPONSIBILITIES OF THE INVESTIGATOR (THE TERM INVESTIGATOR IS USED BROADLY TO DESIGNATE THOSE PEOPLE RESPONSIBLE…
- 4.4 RESPONSIBILITIES OF THE ATTENDING VETERINARIAN (SEE 9 CFR 2.33)
- REFERENCES
- 5 Pain and Distress
- 5.1 DEFINITIONS
- 5.2 CATEGORIES OF PAIN (AVMA, 1986)
- 5.3 PAIN PERCEPTION
- 5.4 ASSESSMENT OF PAIN (AVMA, 1986)
- 5.5 STRESS (NRC, IN PRESS)
- 5.6 DISTRESS (NRC, IN PRESS)
- 5.7 ETHICAL OBLIGATIONS
- 5.8 LEGAL OBLIGATIONS (OVERSEEN BY THE INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE)
- 5.9 ADEQUATE VETERINARY CARE
- REFERENCES
- 6 Anesthetics, Tranquilizers, Analgescis, and Neuromuscular Blocking Agents.
- 6.1 GENERAL ANESTHETICS (LUMB AND JONES, 1984)
- 6.2 TRANQUILIZERS AND SEDATIVES (GLEED, 1987)
- 6.3 Analgesics
- 6.4 NEUROMUSCULAR BLOCKING AGENTS (PARALYTICS OR IMMOBILIZING AGENTS)
- 6.5 FACTORS MODIFYING THE EFFECTS OF TRANQUILIZERS, ANALGESICS, AND NEUROMUSCULAR BLOCKING AGENTS
- 6.6 SAFETY PRECAUTIONS
- 6.7 RECORDKEEPING REQUIREMENTS
- 6.8 FUNCTIONS OF THE ATTENDING VETERINARIAN IN PAIN MANAGEMENT
- REFERENCES
- 7 Survival Surgery and Postsurgical Care
- 7.1 DEFINITIONS
- 7.2 LEGAL REQUIREMENTS (9 CFR 2.31
- PHS, 1986)
- 7.3 PREPARATION FOR SURGERY
- 7.4 ANESTHESIA (SEE SECTION 6.1)
- 7.5 SURGICAL COMPLICATIONS
- 7.6 INCISIONS
- 7.7 POSTSURGICAL CARE
- 7.8 EQUIPMENT: TYPE NEEDED TO PROPERLY SUPPORT SURGICAL PROCEDURES IS DEPENDENT ON A NUMBER OF VARIABLES, INCLUDING THE…
- 7.9 RECORDKEEPING
- REFERENCES
- 8 Euthanasia
- 8.1 DEFINITION
- 8.2 LEGAL REQUIREMENTS
- 8.3 ETHICAL AND HUMANE CONSIDERATIONS
- 8.4 HUMAN CONSIDERATIONS
- 8.5 CRITERIA FOR SELECTION OF METHOD OF EUTHANASIA
- 8.6 Pharmacologic Methods
- 8.7 PHYSICAL METHODS
- 8.8 Carcass Disposal
- REFERENCES
- 9 Husbandry, Care, and the Importance of the Environment
- 9.1 LEGAL REQUIREMENTS FOR HUSBANDRY AND CARE
- 9.2 IMPORTANCE OF PROPER HUSBANDRY AND A STABLE ENVIRONMENT
- 9.3 ENVIRONMENTAL VARIABLES THAT CAN BE CONTROLLED
- 9.4 DEALING WITH EMERGENCIES (E.G., POWER FAILURE, FLOODING, AIR-HANDLINGFAILURE, HEATING OR COOLING FAILURE, FIRE
- REFERENCE
- 10 Species-Specific Overview
- Outline
- 10.1 FACTORS ASSOCIATED WITH SELECTION OF ANIMALS
- 10.2 PROCUREMENT OF ANIMALS
- 10.3 CAGING
- 10.4 ENVIRONMENTAL ENRICHMENT
- 10.5 FOOD
- 10.6 WATER
- 10.7 HANDLING AND RESTRAINT
- 10.8 IDENTIFICATION AND RECORDS
- 10.9 ANIMAL HEALTH
- 10.10 ZOONOSES (DESCRIBE SIGNS AND SYMPTOMS IN ANIMALS AND HUMANS).
- 10.11 SPECIFIC TECHNIQUES: HANDS-ON TRAINING IN TECHNIQUES SUCH AS BLOOD WITHDRAWAL, INJECTIONS, SPE ...
- REFERENCES
- IV RESOURCES
- 1 Sources of Information
- ANIMAL WELFARE INFORMATION CENTER
- NATIONAL LIBRARY OF MEDICINE
- INSTITUTE OF LABORATORY ANIMAL RESOURCES
- FOUNDATION FOR BIOMEDICAL RESEARCH
- CENTER FOR ALTERNATIVES
- CENTER FOR ANIMALS AND PUBLIC POLICY
- 2 Selected Bibliography
- LAWS, POLICIES, AND GUIDELINES
- ETHICS, ANIMAL WELFARE, AND THE USE OF ANIMALS IN BIOMEDICAL RESEARCH, EDUCATION, AND TESTING
- ALTERNATIVES
- INSTITUTIONAL ANIMAL CARE AND USE COMMITTEES
- RECOGNITION AND ALLEVIATION OF PAIN AND DISTRESS
- SURGERY
- EUTHANASIA
- BIOLOGY, HUSBANDRY, AND CARE
- General References (Concerning More than one Species or Subject)
- Species-Specific References
- Carnivores
- Domestic Animals
- Nonhuman Primates
- Rabbits
- Rodents
- Other Animals
- GENETICS AND NOMENCLATURE
- NUTRITION
- OCCUPATIONAL HAZARDS AND LABORATORY SAFETY
- PATHOLOGY AND THERAPY
- General References
- Species-Specific References
- Carnivores
- Domestic Animals
- Fishes
- Nonhuman Primates
- Rabbits and Rodents
- OTHER ANIMALS
- DESIGN OF EDUCATIONAL COURSES
- 3 Audiovisual Materials
- V HOW TO DEVELOP, DELIVER, AND EVALUATE AN EDUCATIONAL PROGRAM
- 1 How to Approach the Task of Education
- EDUCATIONAL GOALS
- SETTING OBJECTIVES
- SELECTING METHODS
- Lectures/Seminars
- Interactive Sessions
- Workshops/Laboratories
- Individualized Study
- Self Assessment
- OVERCOMING RESISTANCE TO CHANGE
- CONCLUSIONS
- 2 How to Plan and Implement a Training Course
- IDENTIFYING THE TARGET AUDIENCE
- ALLOCATING A BUDGET/FUNDING
- DETERMINING GOALS AND OBJECTIVES
- SCHEDULING THE COURSE
- RESERVING FACILITIES
- IDENTIFYING AND CONTACTING LECTURERS
- OBTAINING AND REVIEWING AUDIOVISUAL MATERIALS.
- ASSEMBLING REFERENCE MATERIALS
- PUBLICIZING THE COURSE
- REFERENCES
- 3 Evaluation
- EVALUATING THE INSTITUTIONAL PROGRAM
- EVALUATING THE COURSE
- REFERENCE
- Appendixes
- I Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training
- II The Animal Welfare Information Center
- ANIMAL WELFARE INFORMATION CENTER ESTABLISHED
- SERVICES AND INFORMATION RESOURCES AVAILABLE THROUGH AWIC
- AWIC REFERENCE PUBLICATIONS
- PROJECTS SUPPORTED BY AWIC
- UPDATES REGARDING AWIC AND NAL
- PUBLICATIONS AVAILABLE THROUGH AWIC
- III Sample Objectives or Self-Assessment Statements
- INTRODUCTION
- CORE MODULE
- Laws, Regulations, and Policies That Impact on the Care and Use of Animals
- Ethical and Scientific Issues
- Alternatives
- Responsibilities of the Institution, Animal Care and Use Committee, and Research and Veterinary Staffs
- Pain and Distress
- Anesthetics, Analgesics, Tranquilizers, and Neuromuscular Blocking Agents
- Survival Surgical and Postsurgical Care
- Euthanasia
- Husbandry, Care, and the Importance of the Environment
- Resources
- SPECIES-SPECIFIC MODULE
- Selection and Procurement of Animals
- Husbandry and Care
- Animal Health
- Safety and Health Considerations (Zoonoses)
- Specific Techniques
- Euthanasia
- PAIN-MANAGEMENT MODULE
- Definitions, Mechanisms, and Assessment
- Legal and Ethical Obligations
- Alleviation of Pain or Distress
- Anesthestics
- Euthanasia
- SURGERY MODULE
- Legal Requirements for Survival Surgery
- Aseptic Technique
- Selection and Administration of Anesthetic
- Animal Monitoring
- Surgical Techniques
- Postsurgical Care
- Medical Records
- Terminal Surgeries.