The Arctic Aeromedical Laboratory's thyroid function study : a radiological risk and ethical analysis

The Arctic Aeromedical Laboratory's thyroid function study a radiological risk and ethical analysis

Detalles Bibliográficos
Autores Corporativos: National Research Council (U.S.). Committee on Evaluation of 1950s Air Force Human Health Testing in Alaska Using Radioactive Iodine131 (-), Arctic Aeromedical Laboratory (U.S.)
Formato: Libro electrónico
Idioma:Inglés
Publicado: Washington, D.C. : National Academy Press 1996.
Edición:1st ed
Materias:
Thyroid gland function tests > Health aspects > Alaska.
Iodine > Isotopes > Diagnostic use > Moral and ethical aspects.
Medical ethics > Alaska.
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009820333006719
Tabla de Contenidos:
  • The Arctic Aeromedical Laboratory's Thyroid Function Study: A Radiological Risk and Ethical Analysis
  • Copyright
  • Preface
  • Contents
  • Executive Summary
  • DESCRIPTION OF THE AAL THYROID FUNCTION STUDY
  • HEALTH EFFECTS OF I ADMINISTRATION IN HUMANS
  • THE ETHICS OF HUMAN SUBJECTS RESEARCH
  • CONCLUSIONS AND RECOMMENDATIONS
  • 1 Introduction
  • THE COMMITTEE'S CHARGE
  • THE AAL AND THE THYROID FUNCTION STUDY
  • CONDUCT OF THE STUDY: SAMPLE SIZE AND DISTRIBUTION
  • Alaska Natives
  • Army and Air Force Servicemen
  • CONDUCT OF THE STUDY: SUBJECT SELECTION
  • Wainwright
  • Anaktuvuk Pass
  • Fort Yukon
  • Arctic Village
  • Point Hope
  • Military Testing
  • STUDY RESULTS
  • THE COMMITTEE'S METHODS
  • Written Information
  • Interview and Public Hearing Information
  • COMMON THEMES FROM THE PUBLIC SESSION
  • 2 Health Effects of I Administration in Humans
  • RADIOLOGICAL BACKGROUND OF THE AAL STUDY
  • OVERVIEW OF EPIDEMIOLOGICAL EVIDENCE REGARDING RADIATION-INDUCED THYROID CANCER
  • CALCULATIONS OF RADIATION RISK
  • RISK ESTIMATES FOR THE AAL STUDY
  • SIGNIFICANCE OF CALCULATED RISKS OF RADIATION-INDUCED THYROID CANCER
  • RADIATION GUIDELINES FOR I USAGE-THEN AND NOW
  • 1957 Guidelines
  • Current Guidelines
  • THE EVOLUTION OF OUR UNDERSTANDING OF RADIATION HEALTH EFFECTS
  • 3 The Ethics of Human Subjects Research
  • BACKGROUND
  • Evolution of Ethical Standards
  • The Nuremberg Code
  • After the Code
  • The Evolution of Modern Federal Regulations
  • The Nuremberg Code as Applied to AAL Research in 1955-1957
  • The Common Rule and the AAL Research: Looking Back from the 1990s
  • CONCLUSION
  • 4 Conclusions and Recommendations
  • References
  • Appendix A Thyroid Function in Health and Disease
  • THE HUMAN THYROID
  • ROLE OF IODINE IN THYROID FUNCTION AND DIAGNOSTIC TESTS
  • URINARY AND SALIVARY EXCRETION STUDIES.
  • CONVERSION RATIO AND PLASMA LEVELS OF PBI
  • RACIAL DIFFERENCES IN THYROID FUNCTION
  • UTILIZATION OF I AS A DIAGNOSTIC TOOL
  • CONTRAINDICATIONS TO THE USE OF I
  • Appendix B Summary of the Public Session
  • Appendix C Thyroid Radiation Dose Estimates for I as Determined by the Radiation Internal Dose Information Center, Oak...
  • Appendix D SECRETARY OF DEFENSE Washington
  • Appendix E Informed Consent Elements of Disclosure
  • Appendix F Principles for the Conduct of Research in the Arctic
  • INTRODUCTION
  • IMPLEMENTATION
  • PUBLICATIONS
  • Appendix G Biographical Sketches of Committee Members
  • Appendix H Glossary.

Ejemplares similares