Guideline Optimal serum and red blood cell folate concentrations in women of reproductive age for prevention of neural tube defects
This guideline provides global, evidence-informed recommendations on blood folate concentrations in women of reproductive age for the prevention of neural tube defects in populations. It aims to help Member States and their partners in their efforts to make informed decisions on the appropriate nutr...
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| Formato: | Libro electrónico |
| Idioma: | Inglés |
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Geneva, Switzerland :
World Health Organization
2015.
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| Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009816713906719 |
Tabla de Contenidos:
- Acknowledgements
- Executive summary
- Scope and purpose
- Background
- Determinants of folate status
- Thresholds for folate status in populations
- Measurement of folate status
- Summary of evidence
- Genetic, biological and sociodemographic determinants of folate status (serum, plasma or red blood cell folate) in women of reproductive age
- Blood folate concentrations and risk of neural tube defects
- Response of serum/plasma and red blood cell folate concentrations to nutrition interventions
- Performance of laboratory assays for assessment of folate concentrations
- Recommendations
- Remarks
- Implications for future research
- Dissemination, adaptation and implementation
- Dissemination
- Adaptation and implementation
- Monitoring and evaluation of guideline implementation
- A harmonization programme for folate microbiological assays
- Ethical considerations
- Guideline development process
- Advisory groups
- Scope of the guideline and evidence appraisal
- Management of competing interests
- Plans for updating the guideline
- References
- Annex 1 GRADE "Summary of findings" table
- Annex 2 Summary of guideline development group members' considerations for determining the strength of the recommendations
- Annex 3 WHO steering committee, WHO guideline development group, WHO Secretariat and external resource experts
- Annex 4 Content expert peer-reviewers
- Annex 5 External reviewers (from call for public comments).
