Use of delamanid in the treatment of multidrug-resistant tuberculosis in children and adolescents interim policy guidance

Multidrug-resistant tuberculosis (MDR-TB) is a public health challenge of growing concern. Approximately 580 000 people acquired MDR-TB in 2015, with children accounting for close to 30 000 of MDR-TB cases. The use of delamanid in the treatment of MDR-TB was recommended by the World Health Organizat...

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Detalles Bibliográficos
Otros Autores: Lienhardt, Christian, author (author)
Formato: Libro electrónico
Idioma:Inglés
Publicado: Geneva : World Health Organization 2016.
Materias:
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009816689706719
Tabla de Contenidos:
  • The use of delamanid in the treatment of multidrug-resistant tuberculosis in children and adolescents
  • 1. Background
  • 2. Guideline purpose and target audience
  • 3. Guideline development process
  • 4. Evidence for policy formulation
  • 4.1 Evaluation of paediatric pharmacokinetics data
  • 4.2 Evidence for the safety of delamanid in the treatment of MDR-TB
  • 4.3 Evidence for the efficacy of delamanid in the treatment of MDR-TB
  • 5. Clinical and scientific factors related to the recommendation
  • 6. WHO interim policy recommendations for the use of delamanid in children and adolescents
  • 7.Implementation considerations
  • 8.Updates and further research.