WHO guidelines for the pharmacological and radiotherapeutic management of cancer pain in adults and adolescents

Cancers are among the leading causes of morbidity and mortality worldwide, responsible for 18.1 million new cases and 9.6 million deaths in 2018. Pain is experienced by 55% of patients undergoing anti-cancer treatment and by 66% of patients who have advanced, metastatic, or terminal disease. This ca...

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Detalles Bibliográficos
Autor principal: World Health Organization (author)
Autor Corporativo: World Health Organization, author, issuing body (author)
Formato: Libro electrónico
Idioma:Inglés
Publicado: Geneva : World Health Organization 2018.
Materias:
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009816688506719
Tabla de Contenidos:
  • Abbreviations and Acronyms
  • Executive Summary
  • 1. Introduction
  • 2. Objectives and Target Audience of these Guidelines
  • 3. Scope of the Guidelines
  • 4. Methods used in the Guidelines
  • 5. Cancer Pain Management - Guiding Principles
  • 5.1. The Goal of Optimum Management of Pain is to Reduce Pain to Levels which Allow an Acceptable Quality of Life
  • 5.2. Global Assessment of the Person should Guide Treatment, Recognizing that Individuals Experience and Express Pain Differently
  • 5.3. Safety of Patients, Carers, Health-Care Providers, Communities and Society Must be Assured
  • 5.4. A Pain Management Plan Includes Pharmacological Treatments and May Include Psychosocial and Spiritual Care
  • 5.5. Analgesics, Including Opioids, must be Accessible: Both Available and Affordable
  • 5.6. Administration of Analgesic Medicine should be Given "By Mouth", "By the Clock", "For the Individual" and with "Attention to Detail"
  • 5.7. Cancer Pain Management should be Integrated as Part of Cancer Care
  • 6. Recommendations for the Pharmacological and Radiotherapeutic Management of Cancer Pain in Adults and Adolescents
  • 6.1. Initiation of Pain Relief
  • 6.2. Maintenance of Pain Relief
  • 6.3. Cessation of Opioid Use
  • 6.4. Adjuvant Medicines for Cancer Pain Management
  • 6.5. Management of Bone Pain
  • 7. Research Agenda
  • Interests Declared by Persons Involved in Guideline Development
  • Funding Sources
  • 8. Acknowledgements
  • References
  • Annexes
  • ANNEX 1. Evaluation of Pain
  • ANNEX 2. Systematic Review and Guideline Methods
  • ANNEX 3. Systematic Review Evidence Profiles and Evidence-to-Decision Tables
  • ANNEX 4. Background to the Development of the Guidelines and Details of Personnel
  • ANNEX 5. Opioid Analgesics and International Conventions
  • ANNEX 6. Pharmacological Profiles and Opioid Conversion Tables
  • ANNEX 7. Network Meta-Analysis of Evidence Comparing Analgesics for Cancer Pain Management Initiation & Maintenance and for Breakthrough Cancer Pain
  • ANNEX 8. Glossary.