Principles of human physiology
Otros Autores: | |
---|---|
Formato: | Libro electrónico |
Idioma: | Inglés |
Publicado: |
Harlow, England :
Pearson
2017.
|
Edición: | Sixth edition, Global edition |
Materias: | |
Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009767231706719 |
Tabla de Contenidos:
- Cover
- Title Page
- Copyright Page
- About the Author
- Preface
- Acknowledgments
- Brief Contents
- Contents
- List of Boxes
- 1 Introduction to Physiology
- 1.1 Organization of the Body
- Cells, Tissues, Organs, and Organ Systems
- The Overall Body Plan: A Simplified View
- 1.2 Homeostasis: A Central Organizing Principle of Physiology
- Negative Feedback Control in Homeostasis
- 1.3 The Diabetes Epidemic
- Prevalence of Diabetes
- Obesity and Diabetes
- Classification of Diabetes
- Diagnosing Diabetes Mellitus
- Symptoms of Diabetes Mellitus
- Treatment of Diabetes Mellitus
- Chapter Summary
- Exercises
- 2 The Cell Structure and Function
- 2.1 Biomolecules
- Carbohydrates
- Monosaccharides, Disaccharides, and Polysaccharides
- Lipids
- Amino Acids and Proteins
- Nucleotides and Nucleic Acids
- 2.2 Cell Structure
- Structure of the Plasma Membrane
- Structure of the Nucleus
- Contents of the Cytosol
- Structure of Membranous Organelles
- Structure of Nonmembranous Organelles
- 2.3 Cell-to-Cell Adhesions
- Tight Junctions
- Desmosomes
- Gap Junctions
- 2.4 General Cell Functions
- Metabolism
- Cellular Transport
- Intercellular Communication
- 2.5 Protein Synthesis
- The Role of the Genetic Code
- Transcription
- Destination of Proteins
- Post-translational Processing and Packaging of Proteins
- Regulation of Protein Synthesis
- Protein Degradation
- 2.6 Cell Division
- Replication of DNA
- The Cell Cycle
- Chapter Summary
- Exercises
- 3 Cell Metabolism
- 3.1 Types of Metabolic Reactions
- Hydrolysis and Condensation Reactions
- Phosphorylation and Dephosphorylation Reactions
- Oxidation-Reduction Reactions
- 3.2 Metabolic Reactions and Energy
- Energy and the Laws of Thermodynamics
- Energy Changes in Reactions
- Activation Energy
- 3.3 Reaction Rates.
- Factors Affecting the Rates of Chemical Reactions
- The Role of Enzymes in Chemical Reactions
- 3.4 ATP: The Medium of Energy Exchange
- 3.5 Glucose Oxidation: The Central Reaction of Energy Metabolism
- Coupling Glucose Oxidation to ATP Synthesis
- 3.6 Stages of Glucose Oxidation: Glycolysis, the Krebs Cycle, and Oxidative Phosphorylation
- Glycolysis
- The Krebs Cycle
- Oxidative Phosphorylation
- The Electron Transport Chain
- Summary of Glucose Oxidation
- Glucose Catabolism in the Absence of Oxygen
- 3.7 Energy Storage and Use: Metabolism of Carbohydrates, Fats, and Proteins
- Glycogen Metabolism
- Gluconeogenesis: Formation of New Glucose
- Fat Metabolism
- Protein Metabolism
- Chapter Summary
- Exercises
- 4 Cell Membrane Transport
- 4.1 Factors Affecting the Direction of Transport
- Passive Transport Versus Active Transport
- Driving Forces Acting on Molecules
- 4.2 Rate of Transport
- 4.3 Passive Transport
- Simple Diffusion: Passive Transport Through the Lipid Bilayer
- Facilitated Diffusion: Passive Transport Utilizing Membrane Proteins
- Diffusion Through Channels
- 4.4 Active Transport
- Primary Active Transport
- Secondary Active Transport
- Factors Affecting Rates of Active Transport
- Coexistence of Active and Passive Transport Mechanisms in Cells
- 4.5 Osmosis: Passive Transport of Water Across Membranes
- Osmolarity
- Osmotic Pressure
- Tonicity
- 4.6 Transport of Material Within Membrane-Bound Compartments
- Transport of Molecules into Cells by Endocytosis
- Transport of Molecules Out of Cells by Exocytosis
- 4.7 Epithelial Transport: Movement of Molecules Across Two Membranes
- Epithelial Solute Transport
- Epithelial Structure
- Epithelial Water Transport
- Transcytosis
- Chapter Summary
- Exercises
- 5 Chemical Messengers
- 5.1 Mechanisms of Intercellular Communication.
- Direct Communication Through Gap Junctions
- Indirect Communication Through Chemical Messengers
- 5.2 Chemical Messengers
- Functional Classification of Chemical Messengers
- Chemical Classification of Messengers
- Synthesis and Release of Chemical Messengers
- Transport of Messengers
- 5.3 Signal Transduction Mechanisms
- Properties of Receptors
- Signal Transduction Mechanisms for Responses Mediated by Intracellular Receptors
- Signal Transduction Mechanisms for Responses Mediated by Membrane-Bound Receptors
- 5.4 Long-Distance Communication via the Nervous and Endocrine Systems
- Chapter Summary
- Exercises
- 6 The Endocrine System:Endocrine Glandsand Hormone Actions
- 6.1 Primary Endocrine Organs
- Hypothalamus and Pituitary Gland
- Pineal Gland
- Thyroid Gland and Parathyroid Glands
- Thymus
- Adrenal Glands
- Pancreas
- Gonads
- 6.2 Secondary Endocrine Organs
- 6.3 Hormone Actions at the Target Cell
- Control of Hormone Levels in Blood
- 6.4 Abnormal Secretion of Hormones
- 6.5 Hormone Interactions
- Chapter Summary
- Exercises
- 7 Nerve Cells and Electrical Signaling
- 7.1 Overview of the Nervous System
- 7.2 Cells of the Nervous System
- Neurons
- Glial Cells
- 7.3 Establishment of the Resting Membrane Potential
- Determining the Equilibrium Potentials for Potassium and Sodium Ions
- Resting Membrane Potential of Neurons
- Neurons at Rest
- 7.4 Electrical Signaling Through Changes in Membrane Potential
- Describing Changes in Membrane Potential
- Graded Potentials
- Action Potentials
- Propagation of Action Potentials
- 7.5 Maintaining Neural Stability
- Chapter Summary
- Exercises
- 8 Synaptic Transmission and Neural Integration
- 8.1 Electrical Synapses
- 8.2 Chemical Synapses
- Functional Anatomy of Chemical Synapses
- Signal Transduction Mechanisms at Chemical Synapses.
- Excitatory Synapses
- Inhibitory Synapses
- 8.3 Neural Integration
- Summation
- Frequency Coding
- 8.4 Presynaptic Modulation
- Presynaptic Facilitation
- Presynaptic Inhibition
- 8.5 Neurotransmitters: Structure, Synthesis, and Degradation
- Acetylcholine
- Biogenic Amines
- Purines
- Amino Acid Neurotransmitters
- Neuropeptides
- Unique Neurotransmitters
- Chapter Summary
- Exercises
- 9 The Nervous System:Central Nervous System
- 9.1 General Anatomy of the Central Nervous System
- Glial Cells
- Physical Support of the Central Nervous System
- Blood Supply to the Central Nervous System
- The Blood-Brain Barrier
- Gray Matter and White Matter
- 9.2 The Spinal Cord
- Spinal Nerves
- Spinal Cord Gray and White Matter
- 9.3 The Brain
- Cerebral Cortex
- Subcortical Nuclei
- Diencephalon
- Limbic System
- 9.4 Integrated CNS Function: Involuntary Movement Through Reflexes
- Stretch Reflex
- Withdrawal and Crossed-Extensor Reflexes
- 9.5 Integrated CNS Function: Voluntary Motor Control
- Neural Components for Smooth Voluntary Movements
- Lateral Pathways Control Voluntary Movement
- Ventromedial Pathways Control Voluntary and Involuntary Movements
- The Control of Posture by the Brainstem
- The Role of the Cerebellum in Motor Coordination
- The Basal Nuclei in Motor Control
- 9.6 Integrated CNS Function: Language
- 9.7 Integrated CNS Function: Sleep
- Functions of Sleep
- Sleep-Wake Cycles
- Electrical Activity During Wakefulness and Sleep
- 9.8 Integrated CNS Function: Emotions and Motivation
- 9.9 Integrated CNS Function: Learning and Memory
- Learning
- Memory
- Plasticity in the Nervous System
- Chapter Summary
- Exercises
- 10 The Nervous System: Sensory Systems
- 10.1 General Principles of Sensory Physiology
- Receptor Physiology
- Sensory Pathways
- Sensory Coding.
- 10.2 The Somatosensory System
- Somatosensory Receptors
- The Somatosensory Cortex
- Somatosensory Pathways
- Pain Perception
- 10.3 Vision
- Anatomy of the Eye
- The Nature and Behavior of Light Waves
- Accommodation
- Clinical Defects in Vision
- Regulating the Amount of Light Entering the Eye
- The Retina
- Phototransduction
- Rods versus Cones
- Color Vision
- Light Input to Circadian Rhythms
- Bleaching of Photoreceptors in Light
- Neural Processing in the Retina
- Neural Pathways for Vision
- Parallel Processing in the Visual System
- Depth Perception
- 10.4 The Ear and Hearing
- Anatomy of the Ear
- The Nature of Sound Waves
- Sound Amplification in the Middle Ear
- Signal Transduction for Sound
- Neural Pathways for Sound
- 10.5 The Ear and Equilibrium
- Anatomy of the Vestibular Apparatus
- The Semicircular Canals and the Transduction of Rotation
- The Utricle and Saccule and the Transduction of Linear Acceleration
- Neural Pathways for Equilibrium
- 10.6 Taste
- Anatomy of Taste Buds
- Signal Transduction in Taste
- Neural Pathway for Taste
- 10.7 Olfaction
- Anatomy of the Olfactory System
- Olfactory Signal Transduction
- Neural Pathway for Olfaction
- Chapter Summary
- Exercises
- 11 The Nervous System:Autonomic and MotorSystems
- 11.1 The Autonomic Nervous System
- Dual Innervation in the Autonomic Nervous System
- Anatomy of the Autonomic Nervous System
- Autonomic Neurotransmitters and Receptors
- Autonomic Neuroeffector Junctions
- Regulation of Autonomic Function
- 11.2 The Somatic Nervous System
- Anatomy of the Somatic Nervous System
- The Neuromuscular Junction
- Chapter Summary
- Exercises
- 12 Muscle Physiology
- 12.1 Skeletal Muscle Structure
- Structure at the Cellular Level
- Structure at the Molecular Level
- 12.2 The Mechanism of Force Generation in Muscle.
- The Sliding-Filament Model.