Xenopus : from basic biology to disease models in the genomic era

Xenopus from basic biology to disease models in the genomic era

"Xenopus is unique among the model animals used in the biology. Several books of protocols used Xenopus. Missing is a book taking an historical perspective documenting cell and developmental discoveries and illustrating how Xenopus contributes to the understanding of genes. These topics will be...

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Detalles Bibliográficos
Otros Autores: Fainsod, Abraham, editor (editor), Moody, Sally A., editor
Formato: Libro electrónico
Idioma:Inglés
Publicado: Boca Raton : Taylor & Francis 2022.
Materias:
Xenopus.
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009746164506719
Tabla de Contenidos:
  • Section I.
  • 1. A quick history of Xenopus.
  • 2. The study of cell division controla and DNA replication in Xenopus egg extracts.
  • 3. Maternal gene control of embryogenesis: germ cell determination and germ layer formation.
  • 4. Signaling components in dorsal-ventral patterning and the Organizer.
  • 5. Signaling pathways in anterior-posterior patterning.
  • 6. Wnt signaling in tissue differentiation and morphogenesis.
  • 7. Multiple functions of Notch signaling during early embryogenesis.
  • 8. The development and evolution of the vertebrate neural crest: Insights from Xenopus.
  • 9. The use of Xenopus oocytes to study the biophysics and pharmacological properties of receptors and channels.
  • Section II.
  • 10. The continuing evolution of the Xenopus genome.
  • 11. Dynamics of chromatin remodeling during Xenopus development.
  • 12. Gene regulatory networks controlling Xenopus embryogenesis.
  • 13. The development of high-resolution proteomic analyses in Xenopus.
  • 14. Advances in genome editing tools.
  • Section III.
  • 15. Formation of the left-right axis: insights from the Xenopus model.
  • 16. Discovering the function of congenital heart disease genes.
  • 17. Craniofacial development and disorders - contributions of Xenopus.
  • 18. Modeling digestive and respiratory system development and disease in Xenopus.
  • 19. Functional neurobiology and insights into human disease.
  • 20. Leaping towards the understanding of spinal cord regeneration.
  • 21. Studying tumor formation and regulation in Xenopus.
  • 22. Xenopus: a model to study natural genetic variation and its disease implications.
  • 23. Using Xenopus to understand pluripotency and reprogram cells for therapeutic use. Maternal gene control of embryogenesis.
  • Chapter 8: Sex determination in Xenopus.
  • Section II: Gene Discovery and Disease.
  • Chapter 9: Xenopus and the discovery of developmental genes.
  • Chapter 10: Systems Biology of Xenopus Embryogenesis.
  • Chapter 11: Gene regulatory networks in craniofacial development.
  • Chapter 12: Using Xenopus to discover regulation of GI development and disease.
  • Chapter 13: Using Xenopus to discover the function of congenital heart disease genes.
  • Chapter 14: Using Xenopus to discover the function of congenital kidney disease genes.
  • Chapter 15: Using Xenopus to study genes involved in cancers.
  • Section III: Evolution. Chapter 16: Evolution of amphibians. Chapter 17: Evolution of Xenopus communication. Chapter 18: Evolution of the immune system .
  • Chapter 19: Evolution of the left-right axis.
  • Chapter 20: Evolution of the Xenopus genome.

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